Method for preparing quaternary ammonium salt chitosan and polyvinyl alcohol antibacterial filter composite material

Abstract

The invention discloses a method for preparing a quaternary ammonium salt chitosan and polyvinyl alcohol antibacterial filter composite material. The method is characterized by comprising the following steps: mixing and stirring chitosan powder, acetic acid and deionized water to form a chitosan acetic acid solution; adding isopropyl alcohol, stirring and standing; heating a container through a water bath, and dropwise adding a certain amount of 2,3-epoxypropyltrimethylammonium chloride at set intervals to react; at the end of the reaction, adding absolute ethanol to the container, precipitating, performing suction filtration, and then soaking with acetone, washing, performing suction filtration, and drying to obtain modified quaternary ammonium salt chitosan; preparing a spinning solutionfrom the modified quaternary ammonium salt chitosan, and adding the spinning solution into a polyvinyl alcohol spinning solution to be mixed and stirred to obtain a mixed spinning solution, and obtaining the composite material by an electro-spinning method. The method disclosed by the invention satisfies the development requirements that the material is light and thin, and has good filterabilityand excellent antibacterial performance and the like in practical application, and can be used for preparing biomedical antibacterial protective materials such as biofiltration membranes, protective masks, wound dressings and the like.

Description

technical field [0001] The invention relates to a preparation method of composite material electrostatic blending, in particular to a preparation method of a quaternary ammonium salt chitosan / polyvinyl alcohol antibacterial filtering composite material based on electrostatic spinning technology, and belongs to the technical field of antibacterial filtering materials. Background technique [0002] With the development of industry and technology, the improvement of people's quality of life is also accompanied by environmental pollution. In the past 50 years, environmental pollution has always been the primary problem facing the world. But with the development of economy, environmental problems are becoming more and more serious. Microorganisms play a dual role in real life. Harmful microorganisms such as pathogenic bacteria will cause great harm to human health and life. These microorganisms can multiply rapidly under suitable conditions, spread diseases, and affect the livin...

AI Technical Summary

Problems solved by technology

Due to the inherent biological characteristics of natural materials, it plays an irreplaceable role in the biocompatibility and degradability of antibacterial fibers, so electrospun natural antibacterial fibers have become a research hotspot, and they also occupy a certain proportion in industrial production. , but the heat resistance of natural antibacterial agents is poor, the drug effect period is short, and they are generally biological macromolecules with high relative molecular weight, and their solubility in electrospinning solution is a problem that needs to be solved

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