Detection marker, primer probe pair, kit and detection method for herpesvirus hominis I type and II type

A kit and virus technology, applied in the field of herpes simplex virus type I and/or type II detection markers, can solve the problems of cumbersome operation, difficult to meet early diagnosis, and few applications, so as to improve detection sensitivity and nucleic acid similarity Low, less cross-reactive effects
CN109487013AActive Publication Date: 2019-03-19中生方政生物技术股份有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
中生方政生物技术股份有限公司
Publication Date
2019-03-19

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Abstract

The invention relates to the technical field of detection of pathogenic microorganisms, in particular to a detection marker, primer probe pair, kit and detection method for herpesvirus hominis I typeand II type. By taking reverse repeated sequences RS1 and RS2 in an HSV genome as a target area, the detecting sensitivity can be further improved as two copies are available in the genome on the onehand and cross reactions are unlikely to be caused as the inter-nucleic acid similarity is low on the other hand.
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Description

technical field

[0001] The invention relates to the technical field of detection of pathogenic microorganisms, in particular to a detection marker of herpes simplex virus type I and / or type II, a pair of primers and probes, a kit and a detection method. Background technique

[0002] Herpes simplex is a viral skin disease caused by herpes simplex virus, which can cause various human diseases, such as gingivostomatitis, keratoconjunctivitis, encephalitis, reproductive system infection and neonatal child's infection.

[0003] Herpes simplex virus (HSV) belongs to the subfamily Avirinae of the family Herpesviridae, and the size of the virus plasmid is about 180 nanometers. According to the difference in antigenicity, the virus is currently divided into type I (HSV-1) and type II (HSV-2). HSV-1 is mainly obtained from lip lesions, and can also be isolated from genital lesions, and HSV-2 can be isolated from genital lesions. Infection is due to human-to-human contact, and it is...

Claims

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