Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Zinc-silver-copper coating and preparation method thereof

A copper coating and coating technology, which is used in medical materials, dental implants, joint replacements and filling materials for human tissue defects and the antibacterial field of implant materials, which can solve problems such as poor histocompatibility and infection. , to achieve the effect of promoting wound healing, promoting healing, and improving immunity

Active Publication Date: 2019-04-19
INST OF METAL RESEARCH - CHINESE ACAD OF SCI
View PDF5 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problem of tissue combination and infection of implanted materials, the present invention provides a zinc-silver-copper coating and a preparation method thereof. A zinc-silver-copper coating is prepared on the surface of the prepared solid and porous structure matrix to solve the problems of poor histocompatibility and infection of existing implant materials. The coating obtained by this method has excellent biocompatibility and has Sterilization function

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Zinc-silver-copper coating and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The titanium alloy (Ti-6Al-4V) original sheet is placed in the substrate 5 position in the furnace body 1 of the deposition chamber, and the zinc-silver-copper alloy target is placed in the target 4 position. The Ag content is 0.5%, the Cu content is 0.1%, and the ultimate vacuum (10 -5 Pa), the whole system was repeatedly purged 3 times with argon to ensure that the oxygen content was minimized. Set the bias voltage to 50V, the arc current to 30A, the duty cycle to 20%, and the working air pressure to 1×10 -2 Pa, the deposition time is 30 min, and the thickness of the deposited metal zinc-silver-copper layer is 1 μm. In order to determine the effect of the coating on promoting osteogenesis, an alkaline phosphatase (ALP) experiment was carried out. After culturing for 1 day, 4 days and 7 days, the color of the coating group was darker than that of the matrix group, indicating the activity of alkaline phosphatase in the coating group. higher than that of the matrix gro...

Embodiment 2

[0025] The porous titanium alloy (Ti-6Al-4V) original sheet is placed in the substrate 5 position in the furnace body 1 of the deposition chamber, and the zinc-silver-copper alloy target is placed in the target 4 position. The Ag content is 1.5%, the Cu content is 0.2%, and the ultimate vacuum (10 -5 Pa), the whole system was repeatedly purged 3 times with argon to ensure that the oxygen content was minimized. Set the bias voltage to 55V, the arc current to 40A, the duty cycle to 30%, and the working air pressure to 1×10 -2 Pa, the deposition time is 1 h, and the thickness of the deposited metal zinc-silver-copper layer is 2 μm. Since the substrate is directly placed on the surface of the substrate holder, the bottom of the substrate in contact with the substrate holder cannot deposit the coating. The substrate can be turned over, the bottom is turned up, and the coating is completely covered on the substrate surface. Metal wires can also be used to hang the porous substrate...

Embodiment 3

[0027] Put the planar pure titanium substrate into the substrate 5 position in the furnace body 1 of the deposition chamber, and place the zinc-silver-copper alloy target at the target 4 position. The Ag content is 3%, the Cu content is 0.8%, and the ultimate vacuum (10 -5 Pa), the whole system was repeatedly purged 3 times with argon to ensure that the oxygen content was minimized. Set the bias voltage to 60V, the arc current to 55A, the duty cycle to 40%, and the working air pressure to 1×10 -1 Pa, the deposition time is 1 h, and the thickness of the deposited metal zinc-silver-copper layer is 4 μm. After X-ray diffraction analysis and scanning electron microscope energy spectrum analysis, it is determined that the coating is zinc-silver-copper. Due to the low content of silver and copper, the X-ray spectrum can only show the diffraction information of metal zinc.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Thicknessaaaaaaaaaa
Thicknessaaaaaaaaaa
Thicknessaaaaaaaaaa
Login to View More

Abstract

In order to solve the osseous union and infection problem of implant materials, the invention provides a zinc-silver-copper coating and a preparation method thereof. The method comprises the step thata chemical vapor deposition technology and an evaporation plating technology are adopted for preparing the metallic zinc-silver-copper coating on a solid body or porous matrix made of titanium and titanium alloy or stainless steel or high polymer materials, wherein the thickness of the coating ranges from 0.1 micron to 200 microns, the mass percent of the silver element in the coating is larger than 0% and smaller than or equal to 8%, and the mass percent of the copper element is larger than 0% and smaller than or equal to 2%. According to the zinc-silver-copper coating and the preparation method thereof, the osseous union and infection problem of existing implant materials can be solved, and permanent implant materials obtained through the method can be suitable for the mechanical performance requirements of various implanting positions, have excellent biocompatibility and meanwhile have a sterilization function.

Description

technical field [0001] The invention belongs to the field of medical materials, in particular to dental implants, joint replacements and filling materials for human tissue defects and the antibacterial technical field of implant materials; specifically, the zinc-silver-copper coating material on the surface of the implant and its Preparation. Background technique [0002] Implants such as artificial joints only have a lifespan of 10-15 years due to adverse cell reactions caused by implant loosening and abrasion, which cannot meet the long-term use requirements. Meanwhile, infection remains one of the disastrous postoperative complications of orthopedic implants. Metallic foreign bodies implanted in the body are risk factors for such infections, and a series of in vivo reactions, including the weakening of macrophage function and the passivation of the local immune system, create favorable conditions for the proliferation of pathogens. In addition, the proteins adsorbed on ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C23C14/16C23C14/20C23C14/32
CPCC23C14/16C23C14/20C23C14/325
Inventor 于晓明谭丽丽杨柯
Owner INST OF METAL RESEARCH - CHINESE ACAD OF SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com