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A kind of UV-curable hydrophilic coating and preparation method thereof

A hydrophilic coating and ultraviolet light technology, which is applied in the field of medical coatings, can solve the problems of cumbersome preparation process, cumbersome operation process, and easy peeling off of silica gel substrates, and achieve simple preparation process, wide range of substrates, and high firmness Effect

Active Publication Date: 2022-03-04
辰邦医疗设备(上海)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Patent CN103289499A discloses a hydrophilic resin containing photoactive groups in the polymer chain and a hydrophilic coating prepared by containing a photoactive crosslinking agent. This method requires the synthesis of a special resin, and the preparation process is cumbersome
Patent CN103933616A discloses a method for modifying the top coating, but the cured coating contains acidic groups and needs to be neutralized with ammonia water, and the operation process is cumbersome
Patent CN106540336A discloses a hydrophilic modification coating on the surface of medical interventional catheters. This method is suitable for polyurethane, polyvinyl chloride, polyester, etc., but it is easy to fall off when applied to silica gel substrates.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Preparation method: under ice bath conditions, 5 parts of unsaturated polyurethane acrylate, 2 parts of polyvinyl alcohol, 0.2 part of polyether modified polydimethylsiloxane copolymer, 0.3 part of 2,2-thiodiethyl Bis[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate, 1.0 parts 2-hydroxy-2-methyl-1-[4-(2-hydroxyethoxy)phenyl ]-1-acetone, 20 parts of isopropanol, 71.5 parts of ethanol, the above components are mixed together, fully stirred in a brown bottle for 24 hours to obtain the bottom solution;

[0031] 8 parts of polyvinylpyrrolidone, 2 parts of polyethylene glycol, 1 part of hyaluronic acid, 1 part of polyethylene glycol diacrylate, 0.2 parts of 2-hydroxy-2-methyl-1-[4-(2-hydroxyethyl Oxy)phenyl]-1-propanone, 0.1 part of vinyl bisstearamide, 0.1 part of butyl hydroxyanisole, 87.6 parts of ethanol, mix the above components together, under the condition of 40 degrees, in a brown bottle Stir well for 48 hours to obtain a top layer solution.

[0032] How to use: Imme...

Embodiment 2

[0035] Preparation method: under ice bath conditions, 20 parts of unsaturated polyurethane acrylate, 10 parts of bisphenol A epoxy resin, 0.5 parts of vinyl bis stearamide, 0.2 parts of dibutyl hydroxytoluene, 0.5 parts of benzophenone , 68.8 parts of ethanol, the above components were mixed together, fully stirred in a brown bottle for 24 hours to obtain the bottom solution;

[0036] 15 parts of polyvinylpyrrolidone, 1 part of polyethylene glycol diacrylate, 0.2 parts of benzophenone, 0.1 part of vinylbisstearamide, 0.1 part of N,N'-bis[β-(3,5-di-tert Butyl-4-hydroxyphenyl)propionyl]hydrazine, 83.6 parts of ethanol, the above components were mixed together, under the condition of 40 degrees, fully stirred in a brown bottle for 48 hours to obtain the top layer solution.

[0037] How to use: Immerse the silicone catheter in the bottom layer solution for 5s, pull it out at a speed of 10mm / s, and then irradiate it under a 1000W UV lamp for 90s to obtain a transition layer. The s...

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PUM

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Abstract

The invention discloses a UV-curable hydrophilic coating, which is composed of a primer and a top paint. The primer includes the following components, and the formula ratio is calculated by weight percentage: 2-77 parts of bonding resin, dispersant 0.1 to 1.0 parts, 0.1 to 1.5 parts of antioxidant, 0.1 to 5.0 parts of photoinitiator, 14.5 to 97.3 parts of solvent; the top coating includes the following components, and the formula ratio is by weight percentage: 1 to 15 parts of hydrophilic resin , 0.5-2.5 parts of water-based cross-linking agent, 0.1-5.0 parts of photoinitiator, 0.1-1.0 part of dispersant, 0.1-0.5 part of antioxidant, 79-98.8 parts of solvent; the beneficial effect of the present invention is that the bottom layer of the present invention and The preparation process of the top layer solution is simple, and the materials in the formula are mixed in an ice bath or at room temperature to obtain a hydrophilic coating solution; the bottom layer solution of the present invention is applicable to a wide range of substrates, including silica gel, polyvinyl chloride, stainless steel, polyurethane, poly ester, etc.; the hydrophilic coating of the present invention has low friction and high firmness, and after 30 repeated frictions, the friction does not increase and the coefficient of friction does not decrease.

Description

technical field [0001] The invention relates to the technical field of medical coatings, in particular to an ultraviolet curable hydrophilic coating and a preparation method thereof. Background technique [0002] With the continuous development of medical technology, more and more catheters are used for minimally invasive surgery. Commonly used materials for catheters, such as silica gel, polyvinyl chloride, stainless steel, polyurethane, polyester, etc., have high surface friction and are likely to cause damage to blood vessels and cavities. Complications such as infection and infection, through hydrophilic modification of the catheter, while maintaining the original physical properties of the catheter, the friction coefficient of the catheter surface is reduced, the lubricity of the surface is improved, and the safety during use is improved. . [0003] Regarding the modification of the hydrophilic coating on the surface of the catheter, a number of patents have been repor...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L29/08A61L29/14
Inventor 谭艳霞董双平
Owner 辰邦医疗设备(上海)有限公司
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