Siloxane polymer hydrogel containing strong-water-absorbent side chain, and preparation method thereof

Abstract

The invention discloses a siloxane polymer hydrogel containing a strong-water-absorbent side chain, and relates to the technical field of preparation of hydrogel. The siloxane polymer hydrogel containing the strong-water-absorbent side chain comprises an aminopropylmethyldimethoxysilane monomer, tetramethylammonium hydroxide and a crosslinker polyethylene glycol diacrylate. Siloxane is selected asa main raw material, a silicone chain in the siloxane chain polymer is soft and has a high bond energy, and the side chain is modified to greatly improve the water absorption property. The good waterabsorption property of the side chain compensates the hydrophobic characteristic of the siloxane main chain to some extent, the siloxane chain as the main chain has a chain flexibility, gel with goodmechanical properties can be prepared through chemical crosslinking of the side chain and physical entanglement between the molecular chains, and the siloxane material has good compatibility with organisms, so the medical siloxane hydrogel having good physical and chemical properties can be prepared.

Description

technical field [0001] The invention relates to the technical field of hydrogel preparation, in particular to a siloxane polymer hydrogel containing a strong water-absorbing side chain and a preparation method thereof. Background technique [0002] With the continuous deepening of research on biocompatible polymer hydrogels, higher requirements are put forward for their performance, and people pay more and more attention to the comprehensive performance of materials rather than just the improvement of strength. Especially in the biomedical field, good biomedical materials need to have appropriate water content, biocompatibility, stability and mechanical properties. At the same time, it should have good oxygen permeability and drug loading capacity, etc. In response to these requirements, scholars hope to find a material that can contain these advantages and have excellent performance. [0003] Silicone materials are a class of widely used materials. It has good chain flex...

AI Technical Summary

Problems solved by technology

It has good chain flexibility, while the silicon-oxygen bond has high bond energy, good air permeability, and good biocompatibility and mechanical properties, so it contains excellent properties that most materials do not have, but Its biggest disadvantage is that siloxane is poorly hydrophilic and its polymer chains are relatively hydrophobic, so it is difficult to be used as a biomaterial with a high water content

[0004] Most of the existing siloxane hydrogel materials are prepared by adding water after copolymerization of trimethoxysilane and hydrophilic monomers. The polymerization process is difficult to control, and the ratio of hydrophilicity to comonomers is very different In order to obtain a good hydrophilic siloxane hydrogel, the proportion of siloxane in the copolymer is relatively reduced, so that although the hydrophilicity of the material is increased, its biocompatibility is reduced

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