Anti-H7N9 whole human monoclonal antibody 5G22, and preparation method and application thereof
A monoclonal antibody, fully human technology, applied in the field of immunology, can solve the problems of rimantadine drug resistance and no effective treatment methods, and achieve the goal of reducing cumbersome operations and costs, high affinity and specificity, and low production costs Effect
Active Publication Date: 2019-07-02
SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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Abstract
The present invention relates to an anti-H7N9 whole human monoclonal antibody 5G22, and a preparation method and an application thereof, the anti-H7N9 whole human monoclonal antibody 5G22 or a biologically active fragment derived from the monoclonal antibody and capable of specifically binding H7N9. The antibody has a heavy chain variable region and a light chain variable region. The heavy chain variable region and light chain variable region respectilvey have 3 complementarity determining regions (CDRs). The antibody 5G22 is capable of specifically binding, detecting and neutralizing H7N9 viruses, and more suitable and more promising as a macromolecular drug for treating influenza viruses.
Application Domain
Immunoglobulins against virusesAntivirals +6
Technology Topic
Macromolecular drugHeavy chain +5
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