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Preparing method of composition with natural sun screen performance

A composition and performance technology, applied in medical preparations containing active ingredients, preparations for skin care, pharmaceutical formulations, etc., can solve the problems of non-unique contribution of antioxidant capacity, unstable thermodynamics, long extraction time, etc. It has the advantages of good anti-inflammatory effect, perfect biological activity and simple preparation method

Inactive Publication Date: 2019-07-09
上海绿瑞生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Disadvantages of the prior art: First, according to the mechanism of sun protection, sunscreens are mainly divided into chemical sunscreens and physical sunscreens
[0010] Thirdly, traditional synthetic organic sunscreens cannot relieve and repair the skin after sun exposure. The sunscreen ingredients extracted from natural plants not only have sun protection ability, but also have a high SPF. At the same time, other components have synergistic effects
With the increase of total flavonoid content, the total antioxidant capacity has a rising trend, but the correlation is not significant, that is, the correlation between total flavonoid content and total antioxidant capacity is not like the correlation between total phenols and antioxidant capacity The obvious sexual performance shows that some flavonoids are not unique in their contribution to antioxidant capacity. The synergistic effect of organic acids, polysaccharides and other trace elements together completes a comprehensive antioxidant capacity of the extract.
[0013] Fourth, organic synthetic sunscreens have some disadvantages in compatibility and sticky feeling in use when preparing sunscreen products. Brings an unpleasant feeling, especially in summer, and sunscreen products made of natural sunscreens, whether they are water-in-oil or oil-in-water products, have better stability and skin feel
[0014] Fifth, traditional organic solvents bring solvent residues and solvent side effects, solvent recovery is troublesome and not conducive to energy saving and environmental protection
Although the steam distillation method requires less one-time investment in production equipment, the yield is low and because the extraction is carried out at a temperature above 100°C, the temperature is high. For heat-sensitive substances, secondary chemical reactions are prone to occur, and the extracted components are often not available. It represents the true composition of the original plant extract, but there are problems such as long extraction time and low yield; moreover, due to high-temperature boiling, the relevant chemical components in the remaining medicinal residues also undergo secondary chemical reactions, which cannot completely represent the true composition of the remaining part. The chemical composition and physical properties have also changed greatly, and its reuse is also limited
This is a limitation imposed by traditional extraction methods

Method used

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  • Preparing method of composition with natural sun screen performance
  • Preparing method of composition with natural sun screen performance
  • Preparing method of composition with natural sun screen performance

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] A preparation method of a composition with natural sunscreen performance, comprising the following steps:

[0047](1) First heat part of the water, glycerin, allantoin and carbomer 980 to 90°C in advance, keep it warm for 40 minutes to sterilize, then cool down to 85°C and add the remaining glycerin, allantoin and carbomer 980, stir well Uniformly until the material is dissolved and transparent, keep warm for later use; the raw materials of phase A include 81 parts of water and 0.1 part of carbomer 980 in parts by mass;

[0048] (2) Heat the raw materials of phase B to 88°C, stir and mix evenly, and the raw materials of phase B include in parts by mass: 1 part of glyceryl stearate and 1 part of cetearyl olive oil;

[0049] (3) Slowly pour the homogeneously mixed phase B raw materials into the A phase raw materials, and stir while adding, the stirring speed is 180 rpm, and the temperature is 75°C;

[0050] (4) Carry out homogeneous emulsification of the above-mentioned ...

Embodiment 2

[0054] A preparation method of a composition with natural sunscreen performance, comprising the following steps:

[0055] (1) First heat part of the water, glycerin, allantoin and carbomer 980 to 80°C in advance, keep it warm for 250min to sterilize, then cool down to 75°C and add the remaining glycerin, allantoin and carbomer 980, stir well Uniformly until the material is dissolved and transparent, keep warm for later use; the raw materials of phase A include 79 parts of water and 0.2 parts of carbomer 980 according to the mass parts;

[0056] (2) Heat the raw materials of phase B to 80°C, stir and mix evenly. The raw materials of phase B include: 1.5 parts of PEG-100 stearate, 1.5 parts of sorbitan olive oil, caprylic acid / capric triglyceride 2.5 parts, 0.2 parts of cetearyl alcohol, 0.5 parts of white beeswax

[0057] (3) Slowly pour the homogeneously mixed phase B raw materials into the A phase raw materials, and stir while adding, the stirring speed is 220 rpm, and the t...

Embodiment 3

[0062] A preparation method of a composition with natural sunscreen performance, comprising the following steps:

[0063] (1) First heat part of the water, glycerin, allantoin and carbomer 980 to 87°C in advance, keep it warm for 28 minutes to sterilize, then cool down to 80°C and add the remaining glycerin, allantoin and carbomer 980, stir well Uniformly until the material is dissolved and transparent, keep it warm for later use; the raw materials of phase A include 78 parts of water and 0.18 parts of carbomer 980 in parts by mass;

[0064] (2) Heat the raw materials of phase B to 90°C, stir and mix evenly, the raw materials of phase B include: 0.5 part of glyceryl stearate, 1 part of PEG-100 stearate, cetearyl olive oil acid 0.5 part of ester, 0.5 part of sorbitan olive oil ester, 2 parts of caprylic / capric triglyceride;

[0065] (3) Slowly pour the uniformly mixed phase B raw materials into the phase A raw materials, and stir while adding, the stirring speed is 190 rpm, an...

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Abstract

The invention provides a preparing method of a composition with natural sun screen performance. The preparing method comprises the steps that A-phase raw materials are sterilized, the temperature is adjusted to 75-85 DEG C, and stirring is conducted until the materials are dissolved and the mixture becomes transparent, wherein the A-phase raw materials comprise water and carbomer; B-phase raw materials are heated to 80-90 DEG C and stirred evenly, wherein the B-phase raw materials comprise one or two of glycerol monostearate and PEG-100 stearate and one or two of cetearyl olivate and sorbitanolivate; the B-phase raw materials and the A-phase raw materials are mixed evenly at 75-85 DEG C; homogeneous emulsification is conducted; C-phase raw materials are added and stirred evenly, wherein the C-phase raw materials comprise triethanolamine, a dendrobium officinale extract, a ginger extract, a magnoliae officmalis cortex extract and an angelicae sinensis radix extract. The preparing method is simple and easy to implement, and supercritical CO2 is adopted to extract natural plants, so that the extraction effect is good, and the preparing method is economical and environmentally friendly and saves energy. The prepared composition has high safety and high sun screen capacity.

Description

technical field [0001] The invention relates to a sunscreen product, in particular to a preparation method of a composition with natural sunscreen performance. Background technique [0002] In recent decades, the continuous destruction of the ozone layer has led to a gradual increase in the amount of ultraviolet radiation. As we all know, ultraviolet rays are divided into three categories, including short-wave ultraviolet rays (UVC) at 200-200nm, medium-wavelength ultraviolet rays (UVA) at 280-320nm, and long-wavelength ultraviolet rays (UVB) at 320-400nm. UVC can be completely absorbed by the atmosphere, while UVA and UVB through the atmosphere pose a hazard to human health, especially UVB can lead to skin pigmentation, keratin growth, photoaging, and even skin cancer and immune suppression of the body, excessive UVA ultraviolet rays Light exposure can promote the formation of wrinkles and even cause phototoxic reactions. How to reduce the occurrence of skin diseases effe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9794A61K8/9789A61K8/25A61Q17/04A61Q19/00A61Q17/00
CPCA61K8/25A61K2800/592A61K2800/5922A61K2800/805A61Q17/005A61Q17/04A61Q19/00A61K8/9789A61K8/9794
Inventor 李岗姜春鹏
Owner 上海绿瑞生物科技有限公司
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