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Storage-stable concentrate of disinfectant and application thereof

A disinfectant and stabilizer technology, applied in the field of disinfectants, can solve the problems of limited antimicrobial potential and achieve the effects of wide dilution range, low pollution, and small occupational safety risks

Inactive Publication Date: 2019-07-19
卞保红
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although colloidal silver is relatively stable, its microbicidal potential is very limited because it contains only a small fraction of ionic silver that acts as a microbicide

Method used

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  • Storage-stable concentrate of disinfectant and application thereof
  • Storage-stable concentrate of disinfectant and application thereof
  • Storage-stable concentrate of disinfectant and application thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation Embodiment

[0043] (1) The liquid disinfectant shows a long-lasting antibacterial effect, that is, the "zombie" effect-the silver ions left in the "corpse" of microorganisms continue to have a disinfecting effect. Long-term effectiveness of antimicrobial agents is a desirable characteristic and is particularly suitable for aerosol disinfection, which can be dispersed in the air by a nebulizer to disinfect the entire room.

[0044] (2) Aqueous disinfectant formulations which can be applied to surfaces by sprayers.

[0045] (3) Aerosol preparations which distribute the disinfectant in the air using an atomizer.

[0046] In some embodiments, for making the concentrates of the present invention into aerosol or spray solutions, solvents, propellants, compressed gases including but not limited to ethanol, propylene glycol, dipropylene glycol, ethyl acetate, hexylene glycol, acetone, chlorine Difluoromethane, trifluorofluoroethane, difluoroethane, propane, isobutane, butane, nitrogen, nitrous o...

Embodiment 1

[0051] Basic concentrated solution

[0052] The preparation of silver citrate complex solution: under stirring, 580 grams of anhydrous citric acid are dissolved in 40 ℃ in 940 ml deionized water; Stir and add 25 grams of commercial products trisilver citrate hydrate purchased from Merck at 30 ℃ ( Ag 3 C 6 h 5 o 7 ·xH 2 O) until all the solids are dissolved and the solution is clear, trisilver citrate can also be obtained by e.g. figure 2 Syntheses were prepared by the methods indicated.

[0053] Preparation of the base concentrate: The silver citrate complex solution was mixed with 20 liters of about 55% hydrogen peroxide to form a base concentrate containing 750 ppm silver ion content and 50% hydrogen peroxide.

[0054] Example 1 uses citrate complexes, which can also be replaced by other suitable silver complexes.

Embodiment 2

[0056] At least one stabilizer is premixed with hydrogen peroxide, including but not limited to phosphoric acid, methylglycine diacetic acid (MGDA), N,N-dicarboxymethylglutamic acid tetrasodium salt (GLDA), poly(hexaethylene Methyl biguanide) hydrochloride, polyaspartic acid sodium salt (PASP), add this premixture in the base concentrate in embodiment 1, form embodiment 2 solution, wherein the concentration of stabilizing agent is 0.01~5% w / w.

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Abstract

The invention relates to a storage-stable concentrated solution of disinfectant. The concentrated solution of disinfectant comprises a carboxylate complex silver (I) ions, hydrogen peroxide and a stabilizer, wherein the weight ratio of the carboxylate complex silver (I) ions to the hydrogen peroxide is 1:30 to 1: 50,000. The invention also provides diluents thereof and corresponding applications.Due to the storage-stable concentrated solution of disinfectant of the invention and the application thereof, the storage is stable, and most of the components are selected from natural sources or biodegradable, have little environmental pollution, are suitable for disinfecting delicate and chemically sensitive equipment, have minimal occupational safety risks, and are particularly suitable for the disinfection of semi-critical and critical surfaces and instruments in industries such as healthcare, public health and dental care.

Description

technical field [0001] The invention relates to the field of disinfectants, in particular to a storage-stable disinfectant concentrate and its application. Background technique [0002] Sterilization and disinfection are one of the indispensable links in human production activities, and the use of silver and hydrogen peroxide for sterilization and disinfection has a long history. [0003] The mechanism of antibacterial action of silver is still not completely clear, generally accepted as figure 1 Several actions and bacterial mechanisms are shown: 1, silver (I) ions penetrate the bacterial cell wall and combine with the phospholipid layer of the cytoplasmic membrane; 2, silver (I) ions bind to bacterial DNA, and subsequently destroy DNA replication; 3, silver ( 1) The ion damages the ability of the bacterial ribosome to transcribe RNA information; 4, the silver (I) ion binds to the sulfhydryl group of the bacterial cytochrome B to inactivate the bacterium. [0004] As we a...

Claims

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Application Information

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IPC IPC(8): A01N55/02A01N59/00A01N37/16A01N25/02A01N25/22A01N25/30A01P1/00
CPCA01N25/02A01N25/22A01N25/30A01N37/16A01N55/02A01N59/00
Inventor 卞保红
Owner 卞保红
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