Chitosan-sodium carboxymethyl cellulose layer-by-layer self-assembly probiotics microcapsule and preparation thereof

Abstract

The invention discloses a chitosan-sodium carboxymethyl cellulose layer-by-layer self-assembly probiotics microcapsule and preparation thereof. The chitosan-sodium carboxymethyl cellulose layer-by-layer self-assembly probiotics microcapsule comprises a wall material and a core material wrapped by the wall material. The core material is mainly a mixture formed by probiotics sludge and trehalose, and the wall material is mainly a multilayer structure formed by self-assembling chitosan and sodium carboxymethyl cellulose layer by layer. According to the invention, the detailed structure (particularly the material and the structure adopted by the capsule wall) of the probiotics microcapsule is improved, the whole process of a preparation method is correspondingly designed, the capsule wall formed by polyelectrolyte layer-by-layer self-assembly of chitosan and sodium carboxymethyl cellulose components is utilized, and the obtained chitosan-sodium carboxymethyl cellulose layer-by-layer self-assembly probiotics microcapsule is resistant to acids, resistant to bile salts and resistant to digestive enzymes, improves the stability of probiotics, and can enhance the intestinal planting effectof the probiotics.

Description

technical field [0001] The invention belongs to the technical field of probiotic products, and more specifically relates to a probiotic microcapsule and a preparation method thereof. bacteria microcapsules. Background technique [0002] Probiotics refer to a class of active microorganisms that are beneficial to the host. They are a general term for active beneficial microorganisms that colonize the human intestinal tract and reproductive system and can produce definite health effects, thereby improving the host’s micro-ecological balance and exerting beneficial effects. They are widely used in Bioengineering, industry and agriculture, food safety and life and health fields. Probiotics have the functions of regulating intestinal flora, enhancing the body's immunity, and lowering cholesterol in the human body. At present, a variety of probiotic foods, health foods and medicines have been developed worldwide. [0003] Studies have found that supplementing probiotics to the hu...

AI Technical Summary

Problems solved by technology

The reason may be that the microcapsule wall skeleton is too loose, the structure is porous, and the surface hardness of the microcapsule is small, so that the digestive juice can enter the capsule core and cause the inactivation of probiotics

[0006] And, in the preparation process of existing probiotic microcapsule preparation, in order to ensure the survival rate of bacteria in the preparation process, vacuum freeze-drying method is usually adopted. This method has the advantages of high bacterial survival rate and low temperature, but has low production efficiency and equipment cost. higher disadvantage

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