Bifidobacterium pseudocatenulatum CCFM1045, composition, fermented food, applications, microbial inoculum and preparation method thereof

Abstract

The invention discloses bifidobacterium pseudocatenulatum CCFM1045, a composition, a fermented food, applications, a microbial inoculum and a preparation method thereof. As the bifidobacterium pseudocatenulatum CCFM1045 can tolerate gastrointestinal environments in human bodies, the abnormity of metabolic syndrome mouse serum liver function indexes ALT and AST caused by high-fat diet can be significantly improved; the abnormal oral glucose tolerance of metabolic syndrome mice can be significantly improved as well; area under the curve of glucose tolerance can be reduced; serum insulin levels can be decreased; the rising of triglycerides and total cholesterol content in serum of the metabolic syndrome mice caused by the high-fat diet can be significantly improved; and the rising of Proteusgenus in intestinal tracts caused by the high-fat diet can also be significantly improved. The bifidobacterium pseudocatenulatum CCFM1045 can be used for preparing the pharmaceutical composition and fermented food for alleviating metabolic syndromes and decreasing the occurrence of Parkinson, intestinal infection, urinary tract and kidney infection and other diseases, so that the bifidobacterium pseudocatenulatum CCFM1045 can have very wide application prospects.

Description

technical field [0001] The invention belongs to the technical field of microorganisms, and in particular relates to Bifidobacterium pseudosmall chain CCFM1045, its composition, fermented food, use, bacterial agent and preparation method thereof. Background technique [0002] In recent years, with the continuous development of my country's social and economic level, the living standards of the public have continued to improve, the proportion of carbohydrates and fats in the diet structure has increased day by day, and the restrictions of many working conditions have made it easy for people to develop sedentary behavior Habit. These external environmental factors combined with their own genetic factors have jointly led to the continuous increase in the incidence of metabolic syndrome in the Chinese population. According to reports, between 2002 and 2010, the proportion of people over the age of 20 in China suffering from metabolic syndrome rose from 5.4% to 21.3%, an increase ...

AI Technical Summary

Problems solved by technology

These drugs have a good curative effect on each single risk factor of metabolic syndrome. However, long-term use of drugs has certain side effects. For example, long-term use of metformin can cause irritation to the gastrointestinal tract of some patients and cause discomfort and may affect the patient’s response to vitamin B12. The absorption of rosiglitazone can cause liver function damage and edema, etc.

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