Polyurethane material, preparing method and application thereof, polymer material and 3D stent

Abstract

The invention discloses a polyurethane material, a preparing method and application thereof, a polymer material and a 3D stent, and relates to the technical field of new materials. The polyurethane material is mainly obtained by conducting chain extension on a prepolymer A through a chain extender. The chain extender comprises a carbon material with a hydroxyl group on the surface or similar materials of the carbon material. The prepolymer A has the structure shown in the structural general formula 1, wherein X represents -(CH2CH2)-, or Y represents an optionally-substituted C1-C12 alkyl group, an optionally-substituted C1-C12 naphthenic group, an optionally-substituted C6-C12 aromatic group, an optionally-substituted C6-C12 heterocyclic group or an optionally-substituted C6-C12 heteroarylgroup, m and n represent polymerization degrees, and the number-average molecular weight of the prepolymer A is 250-20000. The carbon material is prepared into amphiphilic polyurethane, the materialcan be modified and enhanced for various organic / inorganic material processing systems, and the mechanical performance and biocompatibility of the material can be remarkably improved.

Description

technical field [0001] The invention relates to the technical field of new materials, in particular to a polyurethane material, its preparation method and application, a polymer material, and a 3D bracket. Background technique [0002] With the introduction of the concept of additive manufacturing, 3D printing technology has developed rapidly in recent years, and has shown good application prospects in the field of biomedicine. It can customize complex tissues and organs and mass-produce them in a programmed and controllable manner. At present, the precision of 3D printing equipment on the market has generally reached the level of 100 microns, and it can even prepare tissue engineering materials in the field of artificial blood vessels in a precise and programmed manner. However, it is relatively difficult to find bioinks suitable for clinical application, because it is necessary to maintain biocompatibility while maintaining good and suitable mechanical properties, and it i...

AI Technical Summary

Problems solved by technology

However, it is relatively difficult to find bioinks suitable for clinical application, because it is necessary to maintain biocompatibility while maintaining good and suitable mechanical properties, and it is necessary to be able to introduce relevant bioactive substances, while chemically synthesized traditional materials It is difficult to meet all the above characteristics

[0003] At present, the development of bio-inks in the field of tissue engineering usually involves chemical modification of the original materials or doping with inorganic-organic active materials, but these existing materials can basically only improve the mechanics, biology or cell adhesion value-added in a targeted manner. A certain aspect of performance limits the application of materials in a wider range

[0004] At present, some bioinks and biomedical materials containing graphene have appeared. Graphene is added to biological materials as a doping material, but due to the aggregation of graphene nanoparticles, it is not easy to disperse in most solvents, and It is easy to agglomerate, so the introduction of graphene in biomedical materials usually relies on chemical modification to improve the dispersion and biocompatibility of graphene

However, simple surface modification can only help graphene to disperse into the matrix material, and the performance improvement of the matrix material is very limited.

In addition, for the processing system of each matrix material, the surface modification of graphene can only be carried out in a targeted manner so that it can be dispersed in the processing system, and the fresh dispersible graphene oxide suitable for various processing systems There are reports

Moreover, the chemical modification process cannot avoid cumbersome reaction steps and various surface modification processes, and the use of toxic reagents is unavoidable, so the time, process and safety costs are increased while introducing graphene.

[0005] At present, there is no modified graphene additive that can be applied to a variety of processing systems. It can uniformly introduce graphene-reinforced materials while endowing the material with special properties, and it is convenient to process and shape the material with the matrix material.

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