Application of euscaphis konishii hayata extract to preparation of hypolipidemic drugs

A technology of Corvus sinensis and blood lipid-lowering drugs, which is applied in the field of the preparation of Corvus sinensis extracts in the preparation of hypolipidemic drugs, can solve the problems of less research on medicinal value, and achieve the improvement of adipose tissue and cell morphology , control weight, control abnormal increase effect
CN110201011AInactive Publication Date: 2019-09-06FUJIAN AGRI & FORESTRY UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
FUJIAN AGRI & FORESTRY UNIV
Publication Date
2019-09-06
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to application of euscaphis konishii hayata extract to preparation of hypolipidemic drugs. According to an ethanol extraction and macroporous adsorption resin extraction preparation method, the euscaphis konishii hayata extract is obtained and capable of effectively inhibiting abnormal weight increase of hyperlipidemia model mice, reducing contents of TC (total cholesterol),TG (triglyceride) and LDL-C (low-density lipoprotein cholesterol) in serum of the hyperlipidemia mice and increasing the content of HDL-C (high-density lipoprotein cholesterol). By observation of liver tissue pathological sections of each group of mice, the euscaphis konishii hayata extract is capable of improving hepatic adipose tissue and cell morphology changes, so that the euscaphis konishii hayata extract has a remarkable hypolipidemic function and can be applied to preparation of medicines for prevention and treatment of hyperlipidemia.
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Description

technical field

[0001] The invention belongs to the field of extraction and application of plant active substances, and in particular relates to the application of the extract of Jacuna dentata in the preparation of blood lipid-lowering medicine. Background technique

[0002] In recent years, due to the rapid development of China's economy, people's material living standards have been greatly improved, and the population of hyperlipidemia has developed rapidly. According to statistics, the population of hyperlipidemia in China has reached 600 million people, accounting for more than 40% of the total. Hyperlipidemia is an important risk factor for arteriosclerosis, cardiovascular disease, and brain disease. It is also an inducement for chronic diseases such as liver fibrosis, fatty liver, and pancreatitis. It has become one of the major hazards to the health of the Chinese population. At present, the treatment of hyperlipidemia is mainly divided into two categories, one is to...

Claims

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