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Prosthesis applied to spinal column and prosthesis preparation method of prosthesis

A spine and prosthesis technology, applied in the field of spine prosthesis and its preparation, can solve problems such as subsidence, no bone available, and inability to fill large bone defects, so as to achieve solid fusion and increase the fusion rate Effect

Pending Publication Date: 2019-09-10
XIAN HONGHUI HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to solve the problem that the amount and shape of autologous bone often cannot meet the requirements of filling large bone defects and the commonly used titanium mesh lacks anti-tumor and anti-infection activities, and the elastic modulus does not match with autologous bone and causes subsidence. The thorny problem of no bone available during large vertebral body lesion resection provides a method that can resist spinal infection and solve the problem that the amount and shape of autogenous bone are often unable to fill large bone defects, especially a prosthesis applied to the spine. Body and prosthesis preparation method thereof

Method used

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  • Prosthesis applied to spinal column and prosthesis preparation method of prosthesis
  • Prosthesis applied to spinal column and prosthesis preparation method of prosthesis
  • Prosthesis applied to spinal column and prosthesis preparation method of prosthesis

Examples

Experimental program
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Embodiment 1

[0038] refer to Figure 1-2 , is a structural schematic diagram of Embodiment 1 of the present invention, a prosthesis applied to the spine, including a base body 1, a hole 2 is opened on the outer wall of the base body 1, and a through hole 2 3 is opened in the vertical direction of the base body 1.

[0039] In actual use:

[0040] In this embodiment, a prosthesis applied to the spine is applied to the vertebrae. Firstly, CT or MRI data of the patient’s defective vertebrae are collected before the operation, and then the external and internal structures of the matrix 1 required are reconstructed with the help of three-dimensional modeling software. At the same time, the three-dimensional The structural design scheme is integrated into the virtual model, and then the base body 1 is printed out, and then the base body 1 is implanted into the defect site.

[0041] In order to satisfy the ingrowth and fusion of new bone tissue, a hole 1 is opened outside the base body 1 to facil...

Embodiment 2

[0044] On the basis of embodiment 1, with reference to Figure 1-4 : The base body 1 is made of titanium alloy.

[0045] In actual use: The porous titanium alloy material provides a good bone substitute material, provides short-term stability and provides space for long-term bone graft fusion.

Embodiment 3

[0047] On the basis of embodiment 1, with reference to Figure 1-4 The method is as follows: there are several holes 1, and the holes 2 are located in the matrix 1 and are all connected. The diameter of the holes 2 is 300-900 μm, and the porosity of the holes 2 is 60%-95%.

[0048] In actual use: the ideal micropore size of the bone tissue engineering scaffold is 300-900 μm, and the porosity is between 60% and 95%, so the diameter of hole 1 and 2 is 300-900 μm, and the porosity of hole 1 and 2 is 60%-95%. Contributes to the ingrowth and fusion of new bone tissue.

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Abstract

The invention relates to the field of medical instruments, in particular to a prosthesis applied to the spinal column. The prosthesis comprises a base body, wherein first holes are formed in the outerwall surface of the base body, and second through holes are formed in the vertical direction of the base body. The purpose of filling a large bone defect part is achieved by the porous titanium alloyprosthesis. By filling the first holes with bone cement and drug-loaded gelatin microspheres, the bone cement is degraded to release drugs resistant to infection, tumor, osteoporosis and the like, disease treatment is achieved, and meanwhile, the growth of bone cells is induced into porous metal to achieve faster and firmer fusion. By filling the second holes with autologous cancellous bone particles, increase of the fusion rate after the prosthesis is implanted is facilitated, and a seed cell basis is provided for the growth of bones in a porous structure. Reinforcement beams around the prosthesis can meet the bearing requirement of the prosthesis at the initial stage after surgery of a patient.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to a prosthesis applied to the spine and a preparation method for the prosthesis. Background technique [0002] Clinically, when spinal tumors, infections (especially tuberculosis), and severe fractures require vertebral body resection and reconstruction surgery, large bone substitute materials are often required to rebuild stability and promote later fusion. Existing materials such as autologous bone, large bone Allograft bone, titanium mesh. However, the amount and shape of autologous bone such as ribs and ilium often cannot meet the requirements of filling large bone defects; with the surge in the number of spinal operations year by year, large allograft bones are increasingly in short supply and have no osteogenic activity; and the commonly used titanium The mesh lacks anti-tumor and anti-infection activities, and the elastic modulus does not match the autogenous bone, causing su...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/44A61F2/30A61L27/06A61L27/12A61L27/22A61L27/36A61L27/54A61L27/56
CPCA61F2/44A61F2/30771A61L27/06A61L27/12A61L27/222A61L27/3608A61L27/56A61L27/54A61F2002/30784A61F2002/2835A61F2240/001A61F2310/00023A61F2310/00952A61F2310/0097A61L2430/02C08L89/00
Inventor 杨小卫郝定均王晓东
Owner XIAN HONGHUI HOSPITAL