Drug balloon

Abstract

The invention discloses a drug balloon. The drug balloon comprises a balloon body and a drug coating, wherein the surface of the balloon body is coated with the drug coating; the drug coating is prepared from a nanofiber net membrane and drug particles, and the interior and the surface of the nanofiber net membrane are evenly coated with the drug particles; and the thickness of the drug coating is5-500 [mu]m. The drug balloon has the beneficial effects that firstly, the specific surface area of the nanofiber net membrane is large, drugs are adsorbed to the surface of the fiber membrane through electrostatic acting force, the drug adsorption capacity is fundamentally improved, the drug adsorption amount is increased greatly, and meanwhile in the balloon conveying and expanding processes, the drugs adsorbed to the outer surface of the balloon body can be kept as far as possible; and secondly, the porosity of the nanofiber net membrane is high and can reach 70% or above, through a uniqueporous interconnection structure, the drugs can be located in the nanofiber net membrane, and in the balloon conveying and expanding processes, the loss of the drugs can be reduced as far as possible.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a drug balloon. Background technique [0002] Drug-coated balloon is an emerging method for the treatment of intraluminal stenosis that has emerged in recent years. It applies anti-stenosis drugs on the surface of the balloon. When the membranes are in contact, the technology of quickly releasing and transferring the drug to the local intima wall by tearing the intima and pressurizing it achieves the purpose of a long-term therapeutic effect through short-term exposure of the drug. [0003] At present, companies such as Braun Medical, Medtronic, Bard, Braun Medical, Beijing Xianruida and Liaoning Yinyi Medical have successively developed drug-coated balloons. Due to the existing surface structure of the balloon, the drug transfer rate on the surface of the balloon Low, in the process of balloon delivery and expansion, the loss of drug is more than 90%, the amount of drug...

AI Technical Summary

Problems solved by technology

[0003] At present, companies such as Braun Medical, Medtronic, Bard, Braun Medical, Beijing Xianruida and Liaoning Yinyi Medical have successively developed drug-coated balloons. Due to the existing surface structure of the balloon, the drug transfer rate on the surface of the balloon Low, in the process of balloon delivery and expansion, the loss of drug is more than 90%, the amount of drug permeated into the blood vessel will directly affect the therapeutic effect, the less the amount of drug contained in the drug coating will affect the effectiveness of the product, At the same time, if the number of shed particles is large, the shed particles are likely to cause complications such as occlusion and embolism of the relatively small cavity or tube body at the distal end, and severe cases may lead to amputation

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