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A kind of traditional Chinese medicine composition for treating swine fever and its preparation method and application

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for treating swine fever and its preparation, can solve the problems of uncured disease, leukopenia, toxic and side effects, etc., to improve pig production performance, simple composition, and improve immune resistance force effect

Active Publication Date: 2022-01-07
河南豫商生物科技集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Other drugs, such as ribavirin, adamantane and other large doses, have relatively large toxic and side effects. As a result, not only did not cure the disease, but it led to a sharp drop in white blood cells, liver and kidney poisoning, and even death

Method used

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  • A kind of traditional Chinese medicine composition for treating swine fever and its preparation method and application
  • A kind of traditional Chinese medicine composition for treating swine fever and its preparation method and application
  • A kind of traditional Chinese medicine composition for treating swine fever and its preparation method and application

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Experimental program
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Effect test

Embodiment 1

[0037] The raw material formula used in this embodiment: rhubarb 15g, Polygonum cuspidatum 10g, Salvia miltiorrhiza 20g, Astragalus 10g, Glauber's salt 5g.

[0038] Take 1 / 2 of the total weight of rhubarb, add 10 times the weight of rhubarb in water, soak once at 90°C for 20 minutes, and obtain rhubarb warm infusion and rhubarb warm soaked medicinal residues;

[0039] Soak the remaining rhubarb, Polygonum cuspidatum, Salvia miltiorrhiza and Astragalus membranaceus in 10 times the weight of water for 1 hour, mix with the dregs of rhubarb warm soaked, add water to decoct twice for 1.5 hours each time, combine the filtrates and concentrate;

[0040] The obtained concentrate, the rhubarb warm infusion and mirabilite were mixed, stirred and dissolved until the final concentration was 2 g of crude drug / mL, and 0.2% by weight of sodium benzoate was added, potted and sterilized to obtain the target traditional Chinese medicine composition. The traditional Chinese medicine used in the ...

experiment example

[0042] Study on Pharmacodynamics of Traditional Chinese Medicine Composition

[0043] 1. Effects on mouse intestinal propulsion in vivo

[0044] 40 mice were randomly divided into 4 groups, 10 in each group. ① The control group was given 0.2mL / 10g body weight of 5% activated carbon suspension. Oral liquid (2) small, (3) medium, (4) high-dose group mice were fed with 0.2 mL / 10 g of 5% activated carbon suspension made from traditional Chinese medicine oral liquid (the doses of Chinese medicine were respectively 5, 10, and 20 g / kg). After 20 minutes of administration, the animals were killed by pulling the neck, and the entire intestinal tube was quickly taken out and spread on a flat plate, and the total length of the small intestine of the mouse and the moving distance of charcoal powder in the intestinal tube were measured.

[0045] Propelling percentage of charcoal powder in the small intestine = moving distance of charcoal powder / full length of small intestine x 100%

[0...

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Abstract

The invention relates to the field of veterinary pharmaceuticals, and discloses a traditional Chinese medicine composition for treating swine fever, a preparation method and application thereof. The traditional Chinese medicine composition is prepared from 1-20 parts by weight of rhubarb, 1-15 parts by weight of polygonum cuspidatum, 1-30 parts by weight of salvia miltiorrhiza, 1-15 parts by weight of astragalus and 1-10 parts by weight of mirabilite. The preparation method comprises: (1) taking 1 / 2 of the total weight of rhubarb, adding 8-12 times the water of the rhubarb medicinal material, and warm soaking to obtain the rhubarb warm infusion and the medicinal residue after the rhubarb warm soak; (2) the remaining Rhubarb, Polygonum cuspidatum, Salvia miltiorrhiza and Astragalus membranaceus are soaked in 8-12 times the amount of water, mixed with the dregs of the rhubarb soaked warmly, decocted with water, filtered, and the obtained filtrate is concentrated; (3) Concentrate the obtained in step (2) The rhubarb warm infusion obtained in step (1) and Glauber's salt are mixed, stirred and dissolved. The traditional Chinese medicine composition of the present invention has the effects of promoting bowel excretion, protecting liver and gallbladder, anti-inflammation, lowering body temperature, anti-toxin and treating swine fever.

Description

technical field [0001] The invention relates to the field of veterinary pharmaceuticals, in particular to a traditional Chinese medicine composition for treating swine fever and its preparation method and application. Background technique [0002] Classical swine fever (Classical swine fever), also known as classical swine fever or classical swine fever, commonly known as "rotten intestinal fever", is caused by the classical swine fever virus of the family Flaviviridae. [0003] Swine fever is an acute, febrile, contact, highly contagious disease. Its characteristics are: it can occur all year round; acute swine fever shows septic changes, solid organ hemorrhage, necrosis and infarction; chronic swine fever shows fibrinous necrotic enteritis. Swine fever can cause fever, anorexia, diarrhea, and death in sick pigs, and sows infected with swine fever will abort or give birth to dead piglets. [0004] At present, swine fever is one of the main infectious diseases threatening ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/708A61P31/14A61K33/04
CPCA61K36/708A61K36/704A61K36/537A61K36/481A61K33/04A61P31/14A61K2236/331A61K2236/39A61K2300/00
Inventor 常明向吴梅梅叶晓川
Owner 河南豫商生物科技集团有限公司
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