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Cranberry micro effervescent tablet and preparation method thereof

A technology of cranberry and cranberry powder is applied in the directions of pharmaceutical formulations, medical preparations with inactive ingredients, medical preparations containing active ingredients, etc. The effect of bacterial resistance generation, reduction of retention, improvement of hygroscopicity and stability

Active Publication Date: 2020-02-11
HANGZHOU WAHAHA TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In view of the defect that the existing oral effervescent tablets need to be disintegrated in water and cannot be directly disintegrated in the oral cavity, the purpose of the present invention is to provide a cranberry micro-effervescent tablet, which can prevent and treat urinary system infection in a targeted manner , can be directly disintegrated in the oral cavity, and the disintegration is gentle, convenient to eat, suitable for oral administration

Method used

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  • Cranberry micro effervescent tablet and preparation method thereof
  • Cranberry micro effervescent tablet and preparation method thereof
  • Cranberry micro effervescent tablet and preparation method thereof

Examples

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Effect test

example 1

[0029] A cranberry micro effervescent tablet, prepared from the following components: cranberry powder 500g, cranberry juice 200g, roselle powder 30g, red raspberry juice powder 150g, resistant dextrin 300g, bicarbonate Sodium 400g, citric acid 300g, magnesium stearate 100g, maltitol 4000g.

[0030] Above-mentioned cranberry micro effervescence tablet is prepared by following process:

[0031] (1) Take cranberry powder, cranberry juice powder, roselle powder, red raspberry juice powder, resistant dextrin, alkali source, acid source, magnesium stearate, sugar alcohol by weighing;

[0032] (2) Pour the weighed resistant dextrin, alkali source, and magnesium stearate into a mixing tank, and mix for 40 minutes at a speed of 30 rpm in a three-dimensional mixer to obtain a premix;

[0033] (3) Pour the weighed cranberry powder, cranberry juice powder, roselle powder, red raspberry juice powder, acid source, sugar alcohol and premix into the mixing tank, and rotate at 30rpm in the thr...

example 2

[0036] A cranberry micro effervescent tablet, prepared from the following components: cranberry powder 450g, cranberry juice powder 500g, roselle powder 20g, red raspberry juice powder 40g, resistant dextrin 250g, carbonic acid Sodium hydrogen 200g, citric acid 100g, maltitol 1500g, sorbitol 1000g, magnesium stearate 20g.

[0037] Above-mentioned cranberry micro effervescence tablet is prepared by following process:

[0038] (1) Take cranberry powder, cranberry juice powder, roselle powder, red raspberry juice powder, resistant dextrin, alkali source, acid source, magnesium stearate, sugar alcohol by weighing;

[0039] (2) Pour the weighed resistant dextrin, alkali source, and magnesium stearate into a mixing tank, and mix for 20 minutes at a speed of 40 rpm in a three-dimensional mixer to obtain a premix;

[0040] (3) Pour the weighed cranberry powder, cranberry juice powder, roselle powder, red raspberry juice powder, acid source, sugar alcohol and premix into the mixing ta...

Embodiment 3

[0043] A cranberry micro effervescent tablet, prepared from the following components: cranberry powder 350g, cranberry juice powder 100g, roselle powder 50g, red raspberry juice powder 80g, resistant dextrin 100g, carbonic acid Sodium hydrogen 220g, citric acid 150g, magnesium stearate 30g, maltitol 1000g, sorbitol 1000g.

[0044] Above-mentioned cranberry micro effervescence tablet is prepared by following process:

[0045] (1) Take cranberry powder, cranberry juice powder, roselle powder, red raspberry juice powder, resistant dextrin, alkali source, acid source, magnesium stearate, sugar alcohol by weighing;

[0046] (2) Pour the weighed resistant dextrin, alkali source, and magnesium stearate into a mixing tank, and mix for 28 minutes at a speed of 40 rpm in a three-dimensional mixer to obtain a premix;

[0047] (3) Pour the weighed cranberry powder, cranberry juice powder, roselle powder, red raspberry juice powder, acid source, sugar alcohol and premix into the mixing ta...

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Abstract

The invention relates to the technical field of food health care, and discloses a cranberry micro effervescent tablet and a preparation method thereof for overcoming the defect that an existing orally-taken effervescent tablet needs to be disintegrated in water and then taken, and cannot be directly disintegrated in the oral cavity. The cranberry effervescent tablet is prepared from the componentsin parts by weight: 350-500 parts of cranberry powder, 50-200 parts of cranberry juice powder, 20-50 parts of roselle powder, 40-150 parts of red raspberry juice powder, 100-300 parts of resistant dextrin, 200-400 parts of an alkali source, 100-300 parts of an acid source, 20-100 parts of magnesium stearate and 2000-4000 parts of sugar alcohol. During preparation, the resistant dextrin is mixed with the alkali source and the magnesium stearate, and then a mixture is tableted. The cranberry effervescent tablet can be disintegrated in the oral cavity to slowly release bubbles, is suitable for being orally taken, convenient to eat, free of irritation and simple in preparation method, can prevent and treat urinary infection and avoid drug resistance of bacteria.

Description

technical field [0001] The invention relates to the technical field of food health care, in particular to a cranberry micro-effervescent tablet and a preparation method thereof. Background technique [0002] Urinary tract infection is an inflammatory response caused by the invasion of pathogenic microorganisms in the urinary tract. It first occurs in women and is one of the most common complications in women. More than 50 percent of women have at least one UTI in their lifetime, and 25 percent have recurrent UTIs. Foreign literature reports that urinary system infection accounts for about 40% of nosocomial infections, ranking first. Domestic literature reports that urinary tract infections account for 20.8% to 31.7% of nosocomial infections, second only to respiratory tract infections. Escherichia coli is the most common pathogen of urinary tract infection, accounting for about 70-95%. Escherichia coli attaches to the surface of bladder epithelial cells, attracting inflam...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/73A61K9/46A61K47/36A61P13/04A61P31/04A23L2/395A23L2/40A23L33/105A23P10/30
CPCA23L2/395A23L2/40A23V2002/00A61K9/0007A61K9/0056A61K9/2059A61K36/185A61K36/45A61K36/73A23L33/105A23P10/30A61P13/04A61P31/04A61K2300/00A23V2200/30A23V2250/5114A23V2250/21
Inventor 陈妮魏振华范恩宇范秋领李言郡余腾斐袁谱龙邓颖颖郝淑娟华川庐
Owner HANGZHOU WAHAHA TECH
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