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Traditional Chinese medicine microecological preparation for preventing and treating livestock diarrhea and preparation method thereof

A technology of traditional Chinese medicine microecology and livestock and poultry diarrhea, which is applied in the field of animal husbandry and biology, can solve the problems of ineffective improvement of immunity, expansion of drug resistance spectrum of Escherichia coli, imbalance of bacterial flora, etc. Reverse, improve animal immunity, improve the effect of inhibition

Active Publication Date: 2020-02-14
DALIAN SANYI ANIMAL MEDICINE CO LTD +1
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Pullorum and fowl typhoid caused by Salmonella have a serious impact on chicken flocks in the poultry industry, and the entire chicken farming cycle is compromised due to intensive rearing
[0004] The current antibiotic treatment of colibacillosis has led to the continuous expansion of the drug-resistant spectrum of E. coli and the decline in the control effect. At the same time, the residue of antibacterial drugs in the body can easily cause bacterial flora imbalance, which not only reduces the quality of meat and egg products, but also affects Human Health and Public Health Security
However, the traditional traditional Chinese medicine compound has no obvious effect on improving immunity due to the slow absorption of the drug effect, and the treatment effect on emergencies is not timely.

Method used

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  • Traditional Chinese medicine microecological preparation for preventing and treating livestock diarrhea and preparation method thereof
  • Traditional Chinese medicine microecological preparation for preventing and treating livestock diarrhea and preparation method thereof
  • Traditional Chinese medicine microecological preparation for preventing and treating livestock diarrhea and preparation method thereof

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preparation example Construction

[0023] The present disclosure provides a preparation method of a traditional Chinese medicine microecological preparation for preventing and treating livestock and poultry diarrhea, the preparation method comprising: inoculating a seed liquid in a culture medium for fermentation; the culture medium contains a compound Chinese medicine extract and a matrix culture medium, and the The seed liquid contains traditional Chinese medicine fermentation strains;

[0024] Wherein, the compound Chinese medicine is composed of Andrographis paniculata, Pulsatilla Radix, Coptidis Rhizoma, Phellodendron Phellodendron, Woody Fragrance, Patrinia and Licorice; Enterococcus faecalis (Enterococcus faecalis) with CGMCC NO: 2196, Bacillus subtilis (Bacillus subtilis) with product number CICC NO: 10020, Candidautilis (Candidautilis) with product number CICC NO: 31170, product number is ACCC NO: 20039 Lactobacillus plantarum, CICC NO: 24498 Clostridium butyricum and ACCC NO: 10649 Rhodosedoseudomouas...

Embodiment 1

[0048] The culture medium component used in the present embodiment comprises the compound Chinese medicine extract of 20 volume % and the base medium of surplus; Wherein the base medium contains: brown sugar 30g / L, glucose 30g / L, honey 30g / L, peptone 3g / L L. Dipotassium hydrogen phosphate 3g / L, sodium acetate 3g / L, magnesium sulfate 0.5g / L, L-cysteine ​​0.5g / L, manganese sulfate 0.15 / L, calcium carbonate 0.20g / L, pH6.0 ~8.0.

[0049] The compound Chinese medicine is: 18 parts of Andrographis paniculata, 15 parts of Pulsatilla, 8 parts of Coptis chinensis, 12 parts of Cortex Phellodendri, 8 parts of Muxiang, 15 parts of Patrinia and 6 parts of licorice. Dry the compound Chinese medicine at 55°C for 2.5h, pulverize it, add 75% ethanol aqueous solution according to the volume ratio of 1:15 for extraction, extract twice, each time for 1h, put the extracted product of the raw material of the traditional Chinese medicine at 4°C for 24h, and then concentrate Become the liquid medici...

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Abstract

The invention provides a preparation method of a traditional Chinese medicine microecological preparation for preventing and treating livestock diarrhea. The preparation method comprises the step of inoculating a seed solution into a culture medium for fermentation; wherein the culture medium contains a compound traditional Chinese medicine extracting solution and a matrix culture medium, and theseed solution contains traditional Chinese medicine fermentation strains. The invention further provides the traditional Chinese medicine microecological preparation for preventing and treating livestock diarrhea and bacillus coagulans CCTCC NO: M2019722. The traditional Chinese medicine microecological preparation is mainly used for preventing and treating livestock diarrhea, has the exact curative effect, greatly reduces the use amount of traditional Chinese medicines through microbial fermentation, saves the management cost of farmers, and has good prevention and treatment effects.

Description

technical field [0001] The application relates to the fields of animal husbandry and biotechnology, in particular to a traditional Chinese medicine microecological preparation for preventing and treating livestock and poultry diarrhea and a preparation method thereof. Background technique [0002] The Ministry of Agriculture of the People's Republic of China announced in the notice on the pilot work of reducing the use of veterinary antimicrobials from 2018 to 2021 that the drug feed additives will be completely withdrawn in 2020, which means that the feed is "antibiotic-free throughout the whole process", which is even more It highlights the importance of provenance purification and improving the immunity of livestock and poultry. At the same time, due to the ubiquity of immune diseases, the use of vaccine immunization has seriously damaged the humoral and cellular immune functions, which also reduces the protective effect of vaccines. [0003] The main pathogenic bacteria...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/84A61P1/12A61P31/04C12N1/20C12R1/07
CPCA61K36/19A61K36/285A61K36/484A61K36/71A61K36/718A61K36/756A61K36/84A61K2236/19A61P1/12A61P31/04C12N1/20C12N1/205C12R2001/07A61K2300/00
Inventor 江国托刘艳顾艳丽单春乔刘秋晨王效禹林洋曹艳子
Owner DALIAN SANYI ANIMAL MEDICINE CO LTD
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