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Breast nodules-eliminating cataplasm and preparation method thereof

A technology of milk addiction and kelp, which is applied in the direction of medical formula, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve problems such as difficulty in achieving technology and technology, destruction of active ingredients of drugs, excessive heavy metals, etc. , to achieve the effects of fast drug onset, long duration of drug effect, and no pollution to clothes

Pending Publication Date: 2020-03-17
SHENYANG HONGYAO GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are few types of Rupi Xiaohei preparations for external use, mainly Rupi Xiaohei plaster, which is to boil Chinese medicinal materials with vegetable oil at high temperature, and then add lead red to a certain extent, until "drops form beads" Then cool down, the tidal flat is on cotton cloth or kraft paper, and it must be heated with a slow fire when using it. This dosage form has a history of thousands of years in our country. This process and dosage form are still in use from folk to regular pharmaceutical factories. With the continuous development of science and technology and the improvement of various detection methods, this dosage form has been gradually eliminated. Its shortcomings include the following points: heavy metals exceed the standard, lead red itself is poisonous; high temperature processing destroys the active ingredients of the drug; heat flow oil is seriously polluted; It is difficult to meet the national GMP standard. Black plaster must be heated when used, sticking to body hair and polluting the skin. There are deficiencies in its allergies, drug content, transdermal absorption rate, sticking strength, controlled and slow release, etc., and its onset is slow. long course of treatment

Method used

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  • Breast nodules-eliminating cataplasm and preparation method thereof
  • Breast nodules-eliminating cataplasm and preparation method thereof
  • Breast nodules-eliminating cataplasm and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A Rupixiao cataplasm, the steps are as follows:

[0023] (1) Preparation of water-extracted medicinal extract: take 300 parts by weight of dandelion, 780 parts by weight of kelp, 80 parts by weight of trichosanthin, 200 parts by weight of Caulis Spatholobus, 60 parts by weight of Radix Paeoniae Rubra, 390 parts by weight of seaweed, and 120 parts by weight of peony , 160 parts by weight of woody fragrance, 280 parts by weight of cortex peony, 200 parts by weight of Prunella vulgaris, 80 parts by weight of forsythia, 120 parts by weight of safflower, extract twice by heating and refluxing with water at a ratio of 1:8 to liquid, the first time Extract for 2 hours, extract for the second time for 1 hour, combine the extracts, concentrate the filtered filtrate under reduced pressure in vacuo, and concentrate to an extract with a relative density of 1.35 as measured by a hydrometer at 45°C to obtain a water-extracted drug extract. Ointment spare;

[0024] (2) Preparation of...

Embodiment 2

[0028] A Rupixiao cataplasm, the steps are as follows:

[0029] (1) Preparation of water-extracted medicinal extract: take 300 parts by weight of dandelion, 780 parts by weight of kelp, 80 parts by weight of trichosanthin, 200 parts by weight of Caulis Spatholobus, 60 parts by weight of Radix Paeoniae Rubra, 390 parts by weight of seaweed, and 120 parts by weight of peony , 160 parts by weight of woody fragrance, 280 parts by weight of cortex peony, 200 parts by weight of Prunella vulgaris, 80 parts by weight of forsythia, 120 parts by weight of safflower, extract twice by heating and refluxing with water at 1:10 by material-liquid weight ratio, the first time Extract for 3 hours, extract for the second time for 2 hours, combine the extracts, concentrate the filtered filtrate under reduced pressure in vacuo, and concentrate to an extract whose relative density is 1.40 as measured by a hydrometer at 55°C to obtain a water-extracted drug extract. Ointment spare;

[0030](2) Pre...

Embodiment 3

[0034] A Rupixiao cataplasm, the steps are as follows:

[0035] (1) Preparation of water-extracted medicinal extract: take 300 parts by weight of dandelion, 780 parts by weight of kelp, 80 parts by weight of trichosanthin, 200 parts by weight of Caulis Spatholobus, 60 parts by weight of Radix Paeoniae Rubra, 390 parts by weight of seaweed, and 120 parts by weight of peony , 160 parts by weight of woody fragrance, 280 parts by weight of cortex peony, 200 parts by weight of Prunella vulgaris, 80 parts by weight of forsythia, 120 parts by weight of safflower, extract twice by heating and refluxing with water at a ratio of 1:9 to liquid, the first time Extract for 2.5 hours, extract for the second time for 1.5 hours, combine the extracts, concentrate the filtered filtrate under vacuum under reduced pressure, and concentrate to an extract with a relative density of 1.37 measured with a hydrometer at 50°C to obtain a water-extracted drug extract. Ointment spare;

[0036] (2) Prepar...

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Abstract

The invention discloses a medicine for treating hyperplasia of mammary glands, and particularly relates to a breast nodules-eliminating cataplasm and a preparation method thereof. The breast nodules-eliminating cataplasm is prepared from the following raw materials: dandelion, antler, kelp, radices trichosanthis, caulis spatholobi, pseudo-ginseng, radix paeoniae rubra, seaweed, uniflower swisscentaury root, elecampane, radix scrophulariae, moutan bark, selfheal, fructus forsythiae, safflower, sodium polyacrylate, chondroitin sulfate, polyvinylpyrrolidone, aluminum dihydroxyaminoacetate, docosahexaenoic acid, glycerol, tartaric acid and sodium carboxymethylcellulose. The cataplasm provided by the invention has the characteristics of large drug loading capacity, strong moisture retention, good compatibility with skin, accurate dosage, repeated uncovering and pasting, and drug administration termination at any time, and has the advantages of high stability and safety, high patient use comfort, fast onset of action, and long drug effect lasting time.

Description

technical field [0001] The present invention relates to a medicine for treating hyperplasia of mammary glands, in particular to Rupixiao babu preparation and its preparation method, which has the functions of promoting blood circulation and removing blood stasis, eliminating blood stasis and dispelling stagnation, and can relieve mammary gland hyperplasia nodules and lumps Efficacy, it belongs to the technical field of traditional Chinese medicine. Background technique [0002] Breast hyperplasia refers to the hyperplasia of breast epithelium and fibrous tissue, the structural degeneration of breast tissue ducts and breast lobules, and the growth of progressive connective tissue. It is the most common breast disease in women. Among the symptoms, breast pain is often distending pain or tingling pain, which can affect one or both breasts, and is more common with one side being more common. Those with severe pain should not touch it, and even affect daily life and work. Pain ...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K36/808A61K47/32A61K47/38A61K47/12A61K47/18A61K47/10A61P15/14A61K35/32A61K31/737
CPCA61K9/7023A61K9/0014A61K36/288A61K35/32A61K36/03A61K36/428A61K36/486A61K36/258A61K36/71A61K36/65A61K36/02A61K36/28A61K36/285A61K36/808A61K36/536A61K36/634A61K36/286A61K31/737A61K47/32A61K47/38A61K47/12A61K47/183A61K47/10A61P15/14A61K2236/331A61K2236/39A61K2236/333A61K2300/00
Inventor 赵喆张春玲
Owner SHENYANG HONGYAO GRP CO LTD
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