Antibacterial Chinese herbal medicine compound preparation, preparation method of antibacterial Chinese herbal medicine compound preparation and hand sanitizer

A compound preparation, Chinese herbal medicine technology, applied in the directions of topical antibacterials, pharmaceutical formulations, skin care preparations, etc. Cocci bactericidal effect and other issues, to achieve good antibacterial effect, good killing effect

Inactive Publication Date: 2020-05-29
SHENZHEN BOTON FLAVORS & FRAGRANCES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The Chinese herbal medicine antibacterial hand sanitizer in the prior art uses relatively single Chinese medicine ingredients, and the prepared Chinese herbal medicine antibacterial hand sanitizer has a bactericidal effect and the effects of decontamination, moisturizing, moisturizing and hand protection, but the sterilizing function of the hand sanitizer is mainly limited to ordinary Pathogenic bacteria, did not show the bactericidal effect on drug-resistant bacteria such as methicillin-resistant staphylococcus, and methicillin-resistant staphylococcus is a kind of superbug. From the perspective of infectious disease prevention and control, outdoors may be a super bacteria. One of the sources of infection of bacteria and other drug-resistant bacteria, and once infected, it poses a greater threat to people with poor immunity, and the current treatment of methicillin-resistant staphylococcus is very troublesome, therefore, it is necessary to prevent infection To prevent this from happening, there should be special requirements for hand sanitizers

Method used

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  • Antibacterial Chinese herbal medicine compound preparation, preparation method of antibacterial Chinese herbal medicine compound preparation and hand sanitizer
  • Antibacterial Chinese herbal medicine compound preparation, preparation method of antibacterial Chinese herbal medicine compound preparation and hand sanitizer
  • Antibacterial Chinese herbal medicine compound preparation, preparation method of antibacterial Chinese herbal medicine compound preparation and hand sanitizer

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preparation example Construction

[0022] The invention provides an antibacterial Chinese herbal medicine compound preparation, which comprises the following proportions by weight: 15-35 parts of Schizonepetae, 2-10 parts of Forsythia, 5-10 parts of bellflower, and 10-20 parts of Arctium , 8-15 parts of licorice, obtained through the preparation method of extraction and purification.

[0023] The antibacterial Chinese herbal medicine compound preparation provided by the embodiment of the present invention is obtained through extraction and purification. These five herbs are the components of many traditional prescriptions for treating respiratory tract infections. In the prescription, Nepeta chinensis, forsythia are fragrant to relieve the exterior, burdock and platycodon grandiflorum are used to clear away heat and detoxify, and licorice harmonizes the medicines. Modern pharmacological studies have confirmed that pulegone in nepeta, forsythin in forsythia, arctiin in arctium, platycodon saponin in bellflower, ...

Embodiment 1

[0036] (1) Weigh 5 parts by weight of Schizonepetae and 1 weight part of Forsythia and grind them to 150 mesh, steam distillation at a material-to-liquid ratio of 1:15, extraction temperature of 90°C, extraction for 4 hours, to obtain Schizonepeta ear oil and Lisianthia chinensis Warp oil;

[0037] (2) Weigh 2 parts by weight of Platycodon grandiflorum, 4 parts by weight of burdock fruit, and 2 parts by weight of licorice medicinal material and pulverize to 150 mesh, add 6-9 times the amount of water to soak for 1-1.5 hours, and extract twice at 90 ° C under reflux. 1.5 hours each time, filter, combine the two filtrates, concentrate to one-tenth of the volume of the extract, add 3 times the volume of 95% ethanol, ethanol precipitation, centrifuge, the supernatant is concentrated to a specific gravity of 1.3, passed through the processed Macroporous resin column, respectively eluted with three column volumes of distilled water and 20% ethanol, discarded, then eluted with 50%-70...

Embodiment 2

[0040] (1) Weigh 5 parts by weight of Schizonepetae and 2 weight parts of Forsythia and grind them to 150 mesh, steam distillation at a material-to-liquid ratio of 1:15, extraction temperature of 90°C, extraction for 4 hours, to obtain Schizonepeta ear oil and Schizonepeta Warp oil;

[0041] (2) Weigh 2 parts by weight of Platycodon grandiflorum, 4 parts by weight of burdock fruit, and 2 parts by weight of licorice medicinal material and pulverize to 150 mesh, add 6-9 times the amount of water to soak for 1-1.5 hours, and extract twice at 90 ° C under reflux. 1.5 hours each time, filter, combine the two filtrates, concentrate to one-tenth of the volume of the extract, add 3 times the volume of 95% ethanol, ethanol precipitation, centrifuge, the supernatant is concentrated to a specific gravity of 1.3, passed through the processed Macroporous resin column, respectively eluted with three column volumes of distilled water and 20% ethanol, discarded, then eluted with 50%-70% ethan...

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Abstract

The invention discloses antibacterial Chinese herbal medicine compound preparation, a preparation method of the antibacterial Chinese herbal medicine compound preparation and a hand sanitizer. The hand sanitizer contains the antibacterial Chinese herbal medicine compound preparation. The antibacterial Chinese herbal medicine compound preparation comprises the following components in the followingparts by weight: 15-35 parts of schizonepeta spike, 2-10 parts of weeping forsythia capsules, 5-10 parts of radix platycodonis, 10-20 parts of great burdock achene, and 8-15 parts of liquorice roots.The hand sanitizer is prepared by the preparation method comprising the steps of carrying out extraction, and carrying out purification; and the hand sanitizer is specifically prepared by mixing extraction liquid of the Chinese herbal medicines schizonepeta spike, weeping forsythia capsules, radix platycodonis, great burdock achene and liquorice roots with a surfactant, a synergist and the like. By optimizing the combination of the Chinese herbal medicines with the other active ingredients, synergistic antibacterial effects can be beneficially achieved so as to endow the hand sanitizer with relatively good bacterium killing effects on common pathogenic staphylococcus aureus and escherichia coli, as well as relatively high antibacterial activity against a resistant bacterium, namely methicillin-resistant staphylococcus; and moreover, the hand sanitizer is elegant in fragrance, free of addition of essence, and reduced in cost.

Description

technical field [0001] The invention relates to the field of hand sanitizer for daily necessities, in particular to an antibacterial Chinese herbal medicine compound preparation, a preparation method and the hand sanitizer. Background technique [0002] In daily life, especially in spring and summer, with the increase of environmental humidity, bacteria and viruses are easy to breed and spread to human skin through various transmission channels. If they are not treated in time, it will cause skin diseases, and Scientific research shows that most bacterial and viral infections occur through hand contact or hand-to-mouth and nose contact. With the improvement of people's health awareness, hand hygiene has also received more and more attention. According to the trend, various antibacterial hand sanitizers have become mainstream products in the market. Most of the antibacterial agents in antibacterial hand sanitizers still come from chemical raw materials, such as triclosan, tri...

Claims

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Application Information

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IPC IPC(8): A61K36/634A61P31/02A61K8/9789A61Q19/10A61Q17/00
CPCA61K36/28A61K36/346A61K36/484A61K36/538A61K36/634A61K2236/331A61K2236/39A61K2236/53A61K2236/55A61K2800/5922A61K2800/805A61Q17/005A61Q19/10A61K8/9789A61P31/02A61K2300/00Y02A50/30
Inventor 王晶宁静陈小敏符鑫李剑政林谦
Owner SHENZHEN BOTON FLAVORS & FRAGRANCES
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