A kind of high acid-resistant vitamin A product and preparation method thereof
A vitamin and acetate technology, applied in pharmaceutical formulations, non-active components of polymer compounds, medical preparations of non-active components, etc., can solve the problems of high pressure and homogenization temperature, difficult industrialization, complicated processes, etc., and achieve acid resistance. The effect of improving the property and stability, increasing the product load and reducing the degree of degradation
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Embodiment 1
[0040] Water phase preparation: Arabic glue 40.4g and glide 14.8g of glueylin are dissolved in 100g of water, adding 0.4g of askthalotic acid and 1.2g of sodium ascorbicate.
[0041] Oil phase preparation: Vitamin A acetate 20.8g and BHT 2.4G are dissolved from light and stirring at 60-65 ° C.
[0042] After the two phases are mixed, the dispersed emulsification is fully stirred and the temperature is 60-65 ° C during the period to obtain an emulsion solution.
[0043] The analogenic liquid at 40 ± 2MPa is high.
[0044] Place the emulsification solution in the constant temperature tank, the control temperature is 60-65 ° C, spray drying, spray dry, and then fluidize and polish to obtain vitamin A acetate micro-capsule.
Embodiment 2
[0046]Water phase preparation: 38.2g of Arabic gel essence of ethyl amber, 15.2g of gloutic syrup is dissolved in 100g of water, adding 0.6g of askthalogenic acid and 0.8g of sodium ascorbicate.
[0047] Oil phase preparation: Vitamin A palmate 23.2g and BHT 2.0g are dissolved from light and stirring at 60-65 ° C.
[0048] After the two phases are mixed, the dispersed emulsification is fully stirred and the temperature is 60-65 ° C during the period to obtain an emulsion solution.
[0049] The analogy of emulsification at 50 ± 2MPa is high.
[0050] Place the emulsification solution in the constant temperature tank, the control temperature is 60-65 ° C, spray drying, spray dry, and then fluidize and polish to obtain vitamin A palmate micro-capsule.
Embodiment 3
[0052] Water phase preparation: 43.5g of Arabic gels in ethyl amber curl acid and 16.0g of gloud syrup is dissolved in 100g of water, adding 0.5g of askthalotic acid, and 1.5g of sodium ascorbicate.
[0053] Oil phase preparation: Vitamin A 15.5g and BHT 3.0G are dissolved from light and stirring at 60-65 ° C.
[0054] After the two phases are mixed, the dispersed emulsification is fully stirred and the temperature is 60-65 ° C during the period to obtain an emulsion solution.
[0055] High pressure on the emulsification solution at 30 ± 2MPa.
[0056] Place the emulsification solution in the constant temperature tank, the control temperature is 60-65 ° C, the spray is dry, the spray is dry, and then the vitamin A microcapsule is obtained by fluidization and polishing.
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