Unlock instant, AI-driven research and patent intelligence for your innovation.

Bioactive glass material for hemostasis and repair and preparation method thereof

A technology of bioactive glass and sodium alginate, which is applied in the fields of pharmaceutical formulation, drug delivery, rayon manufacturing, etc., can solve the problems of unsatisfactory hemostatic effect and poor antibacterial performance, and achieve significant hemostatic effect, no skin irritation, good Biosecurity Effects

Inactive Publication Date: 2021-02-09
楚元(海南)再生医学科技有限公司
View PDF6 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Aiming at the deficiencies of the prior art, the present invention provides a bioactive glass material for hemostatic repair and its preparation method, which solves the problems of poor antibacterial performance and unsatisfactory hemostatic effect of the existing bioactive glass material

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Bioactive glass material for hemostasis and repair and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] see figure 1 , the present invention provides the following technical solutions: a bioactive glass material for hemostasis repair, raw materials are bamboo fiber, sodium alginate, sodium hyaluronate, hard acid, chitosan, bioactive glass, antibacterial agent and dimethyl Composed of silicone oil, the components are calculated in parts by weight: 60 parts of bamboo fiber, 1 part of sodium alginate, 0.1 part of sodium hyaluronate, 25 parts of hard acid, 6 parts of chitosan, 4 parts of bioactive glass, antibacterial agent 1 part and 0.5 part of simethicone.

[0028] Specifically, the bioactive glass includes the following parts by weight: 45% SiO 2 , 5% P 2 o 5 , 20% Na 2 O and 30% CaO, the sum of the contents of each component is 100%.

[0029] Specifically, the particle size of the bioactive glass is 25 μm.

[0030] Specifically, chitosan is chitosan iodine.

[0031] A preparation method of a bioactive glass material for hemostasis repair, comprising the following ...

Embodiment 2

[0040] see figure 1 , the present invention provides the following technical solutions: a bioactive glass material for hemostasis repair, raw materials are bamboo fiber, sodium alginate, sodium hyaluronate, hard acid, chitosan, bioactive glass, antibacterial agent and dimethyl Composed of silicone oil, each component is counted by weight: 80 parts of bamboo fiber, 3 parts of sodium alginate, 0.2 part of sodium hyaluronate, 28 parts of hard acid, 8 parts of chitosan, 6 parts of bioactive glass, antibacterial agent 1.5 parts and 1 part of simethicone.

[0041] Specifically, the bioactive glass includes the following parts by weight: 46% SiO 2 , 4% P 2 o 5 , 22% Na 2 O and 28% CaO, the sum of the contents of each component is 100%.

[0042] Specifically, the particle size of the bioactive glass is 30 μm.

[0043] Specifically, chitosan is any one of chitosan iodine, chitosan quaternary ammonium salt or carboxymethyl chitosan.

[0044] A preparation method of a bioactive gl...

Embodiment 3

[0053] see figure 1 , the present invention provides the following technical solutions: a bioactive glass material for hemostasis repair, raw materials are bamboo fiber, sodium alginate, sodium hyaluronate, hard acid, chitosan, bioactive glass, antibacterial agent and dimethyl Composed of silicone oil, each component is counted by weight: 90 parts of bamboo fiber, 5 parts of sodium alginate, 0.3 part of sodium hyaluronate, 30 parts of hard acid, 10 parts of chitosan, 8 parts of bioactive glass, antibacterial agent 2 parts and 1.5 parts of simethicone.

[0054] Specifically, the bioactive glass includes the following parts by weight: 48% SiO 2 , 6% P 2 o 5 , 23% Na 2 O and 23% CaO, the sum of the contents of each component is 100%.

[0055] Specifically, the particle size of the bioactive glass is 35 μm.

[0056] Specifically, chitosan is carboxymethyl chitosan.

[0057] A preparation method of a bioactive glass material for hemostasis repair, comprising the following st...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle diameteraaaaaaaaaa
particle diameteraaaaaaaaaa
particle diameteraaaaaaaaaa
Login to View More

Abstract

The invention belongs to the technical field of bioactive glass, and particularly relates to a bioactive glass material for hemostasis and repair and a preparation method thereof. The bioactive glassmaterial for hemostasis and repair is prepared from the following raw materials: natural bamboo fibers, sodium alginate, sodium hyaluronate, stearic acid, chitosan, bioactive glass, an antibacterial agent and simethicone. By adding the natural bamboo fibers, the sodium alginate, the sodium hyaluronate, the chitosan, the stearic acid and the bioactive glass for use, the bioactive glass material hasgood lubricating, moisturizing and high antibacterial effects, has a remarkable hemostatic effect, can promote wound healing and has the efficacy of being comfortable and convenient to use; By usingthe simethicone and the antibacterial agent, the bioactive glass material has very high shear resistance, avoids the generation of bubbles in glass, is non-toxic and harmless, reduces the consumptionof antibiotics, silver ions and the like, has very good biological safety, and does not harm a human body.

Description

technical field [0001] The invention relates to the technical field of bioactive glass, in particular to a bioactive glass material for hemostasis repair and a preparation method thereof. Background technique [0002] Glass is an amorphous inorganic non-metallic material, generally made of various inorganic minerals (such as quartz sand, borax, boric acid, barite, barium carbonate, limestone, feldspar, soda ash, etc.) of. Its main components are silicon dioxide and other oxides. Similarly, the manufacturing process of bioactive glass is roughly the same as that of conventional glass. A material that forms a bond with a material. Discovered by Hench in 1969, BAG is a silicate glass composed of basic components such as SiO2, Na2O, CaO and P2O5. The degradation products of bioactive glass can promote the production of growth factors, promote the reproduction of cells, enhance the gene expression of osteoblasts and the growth of bone tissue. It is the only artificial biomate...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/18A61L15/20A61L15/28A61L15/40A61L15/42A61L15/46D01F1/10D01F8/18D04H1/4382D04H1/46
CPCA61L15/18A61L15/20A61L15/28A61L15/40A61L15/42A61L15/46A61L2400/04D01F1/10D01F8/18D04H1/4382D04H1/46C08L5/04C08L5/08
Inventor 范小晴
Owner 楚元(海南)再生医学科技有限公司