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Efficacy promoting composition and application thereof

A composition and efficacy technology, applied in the field of biomedicine, can solve problems such as single effect and promote penetration, and achieve the effects of improving skin surface condition, improving stability, and high-efficiency skin barrier

Active Publication Date: 2021-02-26
BLOOMAGE BIOTECHNOLOGY CORP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] There are many factors that affect the transdermal absorption of cosmetics, mainly including: skin factors, active ingredient structure, substance concentration, cosmetic dosage form, external environment, etc. At present, most of the active ingredients on the market use skin-like active ingredients, change cosmetic dosage forms, etc. to improve the efficacy of cosmetics. Permeability, the effect is single and there are certain limitations in promoting the penetration

Method used

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  • Efficacy promoting composition and application thereof
  • Efficacy promoting composition and application thereof
  • Efficacy promoting composition and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Add 2.5g of high molecular weight sodium hyaluronate (1200kDa) into an appropriate amount of water and stir until completely dissolved; then add 2.5g of hydrolyzed sodium hyaluronate (5kDa) and 1g of acetylated sodium hyaluronate (molecular weight 4kDa, acetyl content 24% ), stir until completely dissolved; add 3g tetrahydromethyl pyrimidine carboxylic acid, 7g ergothioneine, 20g saccharomyces / rice fermentation product filtrate, 1.5g aminobutyric acid, 5g preservatives (pentanediol 2.5g, hexane diol 2.5g), add water to 100g, stir evenly until completely dissolved, and obtain the effect-promoting composition.

[0045] Examples 2-8, Comparative Examples 1-8 are different from Example 1 in the molecular weight or content of high molecular weight sodium hyaluronate, hydrolyzed sodium hyaluronate, acetylated sodium hyaluronate, tetrahydromethyl pyrimidine carboxylate The contents of acid, ergothioneine, yeast / rice fermentation product filtrate, and GABA were different, as sh...

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Abstract

The invention provides an efficacy promoting composition, which is characterized by comprising polymer hyaluronic acid or salt thereof, hydrolyzed hyaluronic acid or salt thereof, acetylated hyaluronic acid or salt thereof, tetrahydropyrimidine or derivative thereof, ergothioneine, yeast / rice fermentation product filtrate and aminobutyric acid. When the efficacy promoting composition provided by the invention is used for moisturizing and repairing the skin, on one hand, the stability of macromolecular functional components can be improved, and the contact time with the skin is prolonged, so that the utilization rate of the macromolecular functional components is increased, the dosage of the functional components is reduced, the cost is saved, and skin irritation caused by excessive dosageof some functional components is reduced; on the other hand, the transdermal absorption effect of the micromolecular functional components can be improved, and the utilization rate of the micromolecular functional components is increased.

Description

technical field [0001] The invention belongs to the field of biomedicine, and in particular relates to an effect-promoting composition and its application. Background technique [0002] The prerequisite for cosmetics to exert their maximum effect is that the active ingredients have good permeability and activity, and improve the utilization rate of active ingredients. [0003] Transdermal absorption of cosmetics refers to the process in which the functional ingredients in cosmetics act on the skin surface or enter the epidermis or dermis according to the effectiveness of the product, and accumulate and play a role in this part. The transdermal absorption of functional ingredients of cosmetics does not need to enter the body circulation through the skin, which is the main difference between it and drugs. For example, the whitening agent in whitening products needs to act on the basal layer of the skin to block the production of melanin; the functional ingredients of anti-agi...

Claims

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Application Information

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IPC IPC(8): A61K8/34A61K8/44A61K8/49A61K8/73A61K8/9728A61K8/9794A61Q19/00
CPCA61K8/735A61K8/4953A61K8/9728A61K8/9794A61K8/4946A61K8/44A61K8/345A61Q19/00A61K2800/85A61Q19/007A61K2800/524
Inventor 蔺虓霄阚洪玲林伶俐董建军邵萌王磊田雪郭学平
Owner BLOOMAGE BIOTECHNOLOGY CORP LTD
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