A kind of anti-caries antibacterial toothpaste containing probiotics and preparation method thereof
A technology for probiotics and toothpaste, applied in the field of daily chemicals, can solve the problems of unstable product paste and weak antibacterial activity, and achieve the effects of avoiding the quality decline of the paste, improving the inhibitory ability and good curative effect.
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Embodiment 1
[0031] Embodiment 1, the preparation of microcapsule
[0032] S1. Dissolving shellac resin in an aqueous sodium carbonate solution with a concentration of 0.1mol / L at 65°C to prepare a saturated shellac resin sodium salt solution, freeze-drying, and grinding to obtain shellac resin sodium salt for later use;
[0033] S2, dissolving carboxymethyl chitosan in water to prepare an aqueous carboxymethyl chitosan solution with a concentration of 0.5 mg / mL; dissolving shellac resin sodium salt in water to prepare a concentration of 3 mg / mL sodium shellac resin Saline solution; the above-mentioned carboxymethyl chitosan aqueous solution and shellac resin sodium salt aqueous solution were mixed, and at room temperature, magnetically stirred for 12 minutes to obtain a shellac resin sodium salt-chitosan complex; the carboxymethyl chitosan and The mass ratio of lac resin sodium salt is 0.22:1;
[0034] S3. Weigh the lac resin sodium salt-chitosan complex, dissolve it in water, add probi...
Embodiment 2
[0036] Embodiment 2, the preparation of microcapsule
[0037] S1. Dissolving the shellac resin in an aqueous solution of sodium carbonate with a concentration of 0.2 mol / L at 60° C. to prepare a saturated sodium shellac resin solution, freeze-drying, and grinding to obtain the sodium shellac resin for later use;
[0038]S2, dissolving carboxymethyl chitosan in water to prepare an aqueous carboxymethyl chitosan solution with a concentration of 0.1 mg / mL; dissolving shellac resin sodium salt in water to prepare a concentration of 1 mg / mL sodium shellac resin Saline solution; the above-mentioned carboxymethyl chitosan aqueous solution and shellac resin sodium salt aqueous solution were mixed, and at room temperature, magnetically stirred for 10 minutes to obtain a shellac resin sodium salt-chitosan complex; the carboxymethyl chitosan and The mass ratio of lac resin sodium salt is 0.1:1;
[0039] S3. Weigh the lac resin sodium salt-chitosan complex, dissolve it in water, add pr...
Embodiment 3
[0041] Embodiment 3, the preparation of microcapsule
[0042] S1. Dissolving the shellac resin in an aqueous solution of sodium carbonate with a concentration of 0.3 mol / L at 60° C. to prepare a saturated sodium shellac resin salt solution, freeze-drying, and grinding to obtain the shellac resin sodium salt for later use;
[0043] S2, dissolving carboxymethyl chitosan in water to prepare an aqueous carboxymethyl chitosan solution with a concentration of 1 mg / mL; dissolving shellac resin sodium salt in water to prepare a concentration of 3 mg / mL shellac resin sodium salt aqueous solution; the above-mentioned carboxymethyl chitosan aqueous solution and lac resin sodium salt aqueous solution were mixed, and at room temperature, magnetically stirred for 10 minutes to obtain a shellac resin sodium salt-chitosan complex; the carboxymethyl chitosan and violet The mass ratio of gum resin sodium salt is 0.35:1;
[0044] S3. Weigh the lac resin sodium salt-chitosan complex, dissolve ...
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