A kind of anti-caries antibacterial toothpaste containing probiotics and preparation method thereof

A technology for probiotics and toothpaste, applied in the field of daily chemicals, can solve the problems of unstable product paste and weak antibacterial activity, and achieve the effects of avoiding the quality decline of the paste, improving the inhibitory ability and good curative effect.

Active Publication Date: 2021-10-08
YIWU AISHANG COMMODITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The technical problem to be solved by the present invention is to overcome the weak antibacterial activity of the existing toothpaste containing inactivated probiotics, and the defects and deficiencies of unstable product paste, to provide a kind of anti-caries and antibacterial toothpaste containing probiotics and Its preparation method, by adding probiotic microcapsules in the toothpaste of the present invention, thereby solved the technical problem existing in the above-mentioned prior art

Method used

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  • A kind of anti-caries antibacterial toothpaste containing probiotics and preparation method thereof
  • A kind of anti-caries antibacterial toothpaste containing probiotics and preparation method thereof
  • A kind of anti-caries antibacterial toothpaste containing probiotics and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0031] Embodiment 1, the preparation of microcapsule

[0032] S1. Dissolving shellac resin in an aqueous sodium carbonate solution with a concentration of 0.1mol / L at 65°C to prepare a saturated shellac resin sodium salt solution, freeze-drying, and grinding to obtain shellac resin sodium salt for later use;

[0033] S2, dissolving carboxymethyl chitosan in water to prepare an aqueous carboxymethyl chitosan solution with a concentration of 0.5 mg / mL; dissolving shellac resin sodium salt in water to prepare a concentration of 3 mg / mL sodium shellac resin Saline solution; the above-mentioned carboxymethyl chitosan aqueous solution and shellac resin sodium salt aqueous solution were mixed, and at room temperature, magnetically stirred for 12 minutes to obtain a shellac resin sodium salt-chitosan complex; the carboxymethyl chitosan and The mass ratio of lac resin sodium salt is 0.22:1;

[0034] S3. Weigh the lac resin sodium salt-chitosan complex, dissolve it in water, add probi...

Embodiment 2

[0036] Embodiment 2, the preparation of microcapsule

[0037] S1. Dissolving the shellac resin in an aqueous solution of sodium carbonate with a concentration of 0.2 mol / L at 60° C. to prepare a saturated sodium shellac resin solution, freeze-drying, and grinding to obtain the sodium shellac resin for later use;

[0038]S2, dissolving carboxymethyl chitosan in water to prepare an aqueous carboxymethyl chitosan solution with a concentration of 0.1 mg / mL; dissolving shellac resin sodium salt in water to prepare a concentration of 1 mg / mL sodium shellac resin Saline solution; the above-mentioned carboxymethyl chitosan aqueous solution and shellac resin sodium salt aqueous solution were mixed, and at room temperature, magnetically stirred for 10 minutes to obtain a shellac resin sodium salt-chitosan complex; the carboxymethyl chitosan and The mass ratio of lac resin sodium salt is 0.1:1;

[0039] S3. Weigh the lac resin sodium salt-chitosan complex, dissolve it in water, add pr...

Embodiment 3

[0041] Embodiment 3, the preparation of microcapsule

[0042] S1. Dissolving the shellac resin in an aqueous solution of sodium carbonate with a concentration of 0.3 mol / L at 60° C. to prepare a saturated sodium shellac resin salt solution, freeze-drying, and grinding to obtain the shellac resin sodium salt for later use;

[0043] S2, dissolving carboxymethyl chitosan in water to prepare an aqueous carboxymethyl chitosan solution with a concentration of 1 mg / mL; dissolving shellac resin sodium salt in water to prepare a concentration of 3 mg / mL shellac resin sodium salt aqueous solution; the above-mentioned carboxymethyl chitosan aqueous solution and lac resin sodium salt aqueous solution were mixed, and at room temperature, magnetically stirred for 10 minutes to obtain a shellac resin sodium salt-chitosan complex; the carboxymethyl chitosan and violet The mass ratio of gum resin sodium salt is 0.35:1;

[0044] S3. Weigh the lac resin sodium salt-chitosan complex, dissolve ...

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Abstract

The invention belongs to the field of daily chemicals, and in particular relates to an anti-caries toothpaste containing probiotics and a preparation method thereof. 22~50%, glycerin 3~12%, sodium lauryl sulfate 0.5~2.5%, hydroxymethylcellulose sodium 0.1~1%, xanthan gum 0.1~1.5%, sodium saccharin 0.1~1.5%, preservative 0.01% ~0.06%, 0.1~1% tetrasodium pyrophosphate, 0.1~0.5% sodium chloride, 1~5% sodium lauroyl sarcosinate, 0.1~1.2% essence and the balance deionized water. The toothpaste provided by the invention is added with various probiotics capable of inhibiting oral pathogenic bacteria, which can secrete various antibacterial substances, maintain the micro-ecological balance in the oral cavity, and have good curative effect on gingivitis and halitosis.

Description

technical field [0001] The invention belongs to the technical field of daily chemicals. More specifically, it relates to an anti-caries and antibacterial toothpaste containing probiotics and a preparation method thereof. Background technique [0002] The human oral cavity is a complete ecosystem, in which a variety of microorganisms such as bacteria, fungi, mycoplasma, protozoa and viruses are colonized. In the oral cavity, the oral cavity can only maintain a healthy state if a good ecological balance is maintained between the microorganisms and the oral tissue of the host. If the proportion increases, the original oral ecological balance will be broken, and flora imbalance will appear. Therefore, the oral micro-ecological balance has a very close relationship with the health and diseases of the oral cavity. For example, the occurrence of dental caries is mainly related to the significant increase in the proportion of bacteria on the enamel surface of Streptococcus mutans ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/99A61K8/11A61K8/73A61K8/92A61Q11/00A61Q17/00A61P1/02A61P31/02
CPCA61K8/11A61K8/736A61K8/927A61K8/99A61K2800/56A61K2800/592A61Q11/00A61Q17/005A61P1/02A61P31/02A61P31/04
Inventor 钟达金
Owner YIWU AISHANG COMMODITY
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