Traditional Chinese medicine plaster for treating hyperplasia of mammary glands and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine plaster for treating hyperplasia of mammary glands and a preparation method of the traditional Chinese medicine plaster. The traditional Chinese medicine plaster comprises a backing layer, a plaster body layer and a protective layer which are sequentially arranged in an attached mode. The raw materials of the plaster body layer comprise a traditional Chinese medicine extract and a hydrogel matrix; the hydrogel matrix is prepared from the following components in parts by weight: 35 to 45 parts of sodium carboxymethyl cellulose, 25 to 30 parts of a polydopamine modified nano material, 8 to 12 parts of glucolactone, 30 to 40 parts of a humectant and 8 to 10 parts of a transdermal enhancer; and the polydopamine modified nano material comprises a polydopamine modified metal organic framework material and a polydopamine modified far infrared ceramic powder. According to the invention, the hydrogel modified by the nano material modified by polydopamine is used as a matrix, and the traditional Chinese medicine components are made into the cataplasm plaster, so that the irritation of the plaster to a human body is reduced, and the prepared plaster has good drug release property, proper viscosity and low possibility of remaining on skin, and has a far infrared physiotherapy effect.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine plasters, in particular to a traditional Chinese medicine plaster for treating mammary gland hyperplasia and a preparation method thereof. Background technique [0002] Mammary gland hyperplasia refers to hyperplasia of mammary gland epithelium and fibrous tissue, structural degeneration of breast tissue ducts and lobules, and progressive growth of connective tissue. The main cause of the disease is endocrine hormone imbalance. Mammary gland hyperplasia is the most common breast disease in women, and its incidence rate accounts for the first place in breast diseases. In recent years, the incidence of the disease has been increasing year by year, and the age is getting younger and younger. According to the survey, about 70-80% of women have different degrees of breast hyperplasia, which is more common in women aged 25-45. At present, there are many ways to treat hyperplasia o...

AI Technical Summary

Problems solved by technology

[0005] The present invention aims to overcome the fact that hot-melt adhesives are generally used as substrates in the plasters for the treatment of mammary gland hyperplasia in the prior art, and the components of Chinese medicines in the hot-melt adhesive plasters are easily inactivated at high temperatures during processing, which affects the curative effect; and the hot-melt adhesives The plaster is prone to allergies, and it is easy to stick body hair when it is peeled off, causing discomfort to the patient. A traditional Chinese medicine plaster for the treatment of mammary gland hyperplasia and its preparation method are provided. The hydrogel modified by polydopamine-modified nanomaterials is used as the matrix. The traditional Chinese medicine components for the treatment of mammary gland hyperplasia are made into cataplasm patch, which avoids the inactivation of the traditional Chinese medicine components in the preparation process of the plaster, and reduces the irritation of the plaster to the human body, and the prepared plaster has good Excellent drug release, and suitable viscosity, not easy to remain on the skin

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