Tricholoma-matsutake essential oil bacteriostatic gel and preparation method therefor

A technology for essential oils and matsutake mushrooms, applied in antibacterial drugs, pharmaceutical formulations, antifungal agents, etc., can solve problems such as high cost, abnormal odor of leucorrhea, and itching.

Pending Publication Date: 2021-08-20
云南西草资源开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, because the killing process not only kills the harmful bacteria in the private parts, but also kills the beneficial bacteria, long-term use will lead to dry skin, itching, abnormal vaginal discharge, etc., and most antibacterial gel products add more The ingredients of traditional Chinese medicine cause the product to have a certain pungent smell, and the cost is high, which affects the promotion of antibacterial gel products

Method used

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  • Tricholoma-matsutake essential oil bacteriostatic gel and preparation method therefor
  • Tricholoma-matsutake essential oil bacteriostatic gel and preparation method therefor
  • Tricholoma-matsutake essential oil bacteriostatic gel and preparation method therefor

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Preparation method of matsutake essential oil:

[0024] Wash, dry and crush matsutake fruiting bodies, pass through a 40-mesh sieve, put 2g matsutake seeds into a solution of papain (enzyme activity: 800U / mg) with a mass fraction of 2%, and treat them in a water bath at a temperature of 50°C 5h, then add an appropriate amount of ethanol solution with a volume fraction of 95%, use a Soxhlet extractor to extract, control the extraction temperature to ensure that the number of refluxes per hour is 8 times, after 5h of extraction, concentrate the liquid to 100mL, and extract Liquid 25mL, placed in a constant weight evaporating dish. Place the evaporating dish on a water bath to evaporate to dryness, put it in an oven at 105°C for 3 hours, cool it in a drying dish for 30 minutes, weigh it quickly after taking it out, and calculate the yield of essential oil to be 14.58%.

Embodiment 2

[0026] Preparation method of matsutake essential oil:

[0027] Wash, dry and crush matsutake fruit bodies, pass through a 40-mesh sieve, put 2g matsutake seeds into a solution of papain (enzyme activity: 800U / mg) with a mass fraction of 2%, and treat them in a water bath at a temperature of 45°C 6h, then add an appropriate amount of ethanol solution with a volume fraction of 95%, use a Soxhlet extractor to extract, control the extraction temperature to ensure that the number of refluxes per hour is 8 times, after 5h of extraction, concentrate the liquid to 100mL, and extract Liquid 25mL, placed in a constant weight evaporating dish. Place the evaporating dish on a water bath to evaporate to dryness, put it in an oven at 105°C for 3 hours, cool it in a drying dish for 30 minutes, weigh it quickly after taking it out, and calculate the yield of essential oil to be 12.16%.

Embodiment 3

[0029] Preparation method of matsutake essential oil:

[0030] Wash, dry and crush matsutake fruiting bodies, pass through a 40-mesh sieve, put 2g matsutake seeds into a solution of papain (enzyme activity: 800U / mg) with a mass fraction of 3%, and treat them in a water bath at a temperature of 50°C 5h, then add an appropriate amount of ethanol solution with a volume fraction of 95%, use a Soxhlet extractor to extract, control the extraction temperature to ensure that the number of refluxes per hour is 8 times, after 5h of extraction, concentrate the liquid to 100mL, and extract Liquid 25mL, placed in a constant weight evaporating dish. Place the evaporating dish on a water bath to evaporate to dryness, put it in an oven at 105°C for 3 hours, cool it in a drying dish for 30 minutes, weigh it quickly after taking it out, and calculate the yield of essential oil to be 16.85%.

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Abstract

The invention belongs to the technical field of cosmetics and discloses tricholoma-matsutake essential oil bacteriostatic gel and a preparation method therefor. The tricholoma-matsutake essential oil bacteriostatic gel is prepared from the following raw material ingredients in percentage by mass: 4%-10% of tricholoma-matsutake essential oil, 1%-7% of burdock seed oil, 0.5%-1.5% of glycerin, 0.2%-0.6% of carbomer, 0.02%-0.1% of xanthan gum, 0.2%-1.0% of arginine, 0.2%-1.0% of triethanolamine and the balance of water. According to the tricholoma-matsutake essential oil bacteriostatic gel and the preparation method therefor, the tricholoma-matsutake essential oil and the burdock seed oil are added into a formula and are slow in metabolism and long in reversed time in vivo, and thus, the antibacterial effect is improved; meanwhile, the essential oil can also be used for lubricating skin and enable the water retention property of the skin to be good, in case of long-term use, dryness of vaginal skin cannot be caused, and the skin can generate plump, moist and resilient sense; and the tricholoma-matsutake essential oil is graceful in flavor and has a natural delighted feeling.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and relates to a matsutake essential oil antibacterial gel and a preparation method thereof. Background technique [0002] The female reproductive tract is one of the four major micro-ecosystems of the female body. Due to external infections and changes in internal factors, the micro-ecological imbalance of the probiotic flora in women is caused, leading to vulvar, vaginal, uterine, fallopian tube, and ovarian diseases. Gynecological antibacterial gel is a kind of gynecological medicine, which is used for the treatment of various gynecological vaginitis and cervicitis, including: bacterial vaginosis, trichomonal vaginitis, mixed vaginitis, gonococcal infection, chronic cervicitis, It has anti-inflammatory, bactericidal and antipruritic effects. It has obvious inhibitory effect on the growth of Staphylococcus aureus, Escherichia coli, Neisseria gonorrhoeae, Candida albicans and other pathogenic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/92A61K8/34A61K8/41A61K8/44A61K8/73A61K8/81A61K8/04A61K9/06A61K36/28A61K47/36A61P15/02A61P31/04A61P31/10A61P33/02A61Q17/00A61Q19/00A61K36/07
CPCA61K8/922A61K8/8147A61K8/73A61K8/44A61K8/41A61K8/345A61K8/042A61Q19/00A61Q17/005A61K36/07A61K36/28A61K9/06A61K47/36A61P15/02A61P31/04A61P31/10A61P33/02A61K2800/805A61K2300/00
Inventor 孙秋丁瑞耿菲菲杨金凤李丽琴黄丽娟陈旭红赵平舟
Owner 云南西草资源开发有限公司
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