13 results about "Propolin H" patented technology

The invention provides an essence lotion with an anti-aging function and a preparation method thereof, and belongs to the technical field of cosmetics, the essence lotion comprises a phase A, a phase B, a phase C and a phase D, wherein the phase A consists of glyceryl distearate, jojoba oil and vitamin E; the phase B is prepared from deionized water, glycerol, 1, 3-propylene glycol, methylparaben and polyoxyethylene sorbitan monooleate; the phase C is a citric acid solution; and the phase D consists of exosomes from four fruit sources of blueberries, pomegranates, lemons and grapefruits. According to the technical scheme, exosomes from blueberries, pomegranates, lemons and grapefruits are scientifically compounded, an anti-aging network with a synergistic effect is constructed, good stability and biocompatibility are achieved, and many problems existing in traditional anti-aging cosmetic ingredients are solved.

A Lac‑Phe‑based composition, a health care supplement, and a use thereof. The composition comprises propylene glycol, glycerol, Lac-Phe and a synergist in a mass ratio of (0.1-100):(0.1-100):(0.1-10):(0.1-2). The solubility of Lac-Phe is improved and the absorption rate of active pharmaceutical molecules in the body is optimized, thereby enhancing the bioavailability and helping to improve the efficacy of Lac-Phe in preventing and treating obesity.

According to the method disclosed by the invention, the contents of cyanidin-3-O-glucoside, delphinidin-3-O-glucoside and quercetin-3-glucoside in the fresh lonicera caerulea fruits are extracted and determined by applying a ternary eutectic solvent and combining a microwave extraction method. The monomers extracted by the method disclosed by the invention are relatively high in content and very stable. A single factor test carries out orthogonal optimization on selection of the type, the molar ratio, the water content, the solid-to-liquid ratio, the microwave extraction temperature and the microwave extraction time of the ternary eutectic solvent, and an orthogonal test shows that when betaine-glycerol-glucose (Bet-Gly-Glu) with the molar ratio of 1: 3: 1, the water content is 40%, the liquid-to-solid ratio is 20: 1, the extraction temperature is 50 DEG C and the extraction time is 15 min, the content of the glycine betaine is 40%, and the content of the glycine betaine is 40%. The content of the extracted cyanidin-3-O-glucoside is the highest, and the content of the extracted cyanidin-3-O-glucoside is 12.30 mg / g to 12.35 mg / g; the content of the delphinidin-3-O-glucoside is 12.60 mg / g to 12.65 mg / g; the content of the quercetin-3-glucoside is 0.55 mg / g to 0.60 mg / g. The extracted fresh lonicera caerulea fruit pulp extracting solution has relatively high antioxidant and hypoglycemic activity, and can be applied to the fields of antioxidant and hypoglycemic.

The invention relates to the technical field of traditional Chinese medicine gels. The invention provides gel for treating gynecological inflammation and a preparation method thereof. The gel is prepared from the following raw materials in parts by weight: 75 to 85 parts of traditional Chinese medicine extracting solution, 6 to 10 parts of glycerol, 0.2 to 0.4 part of sodium carboxymethyl cellulose, 0.3 to 0.5 part of carbomer and 3 to 4 parts of sodium alginate. The traditional Chinese medicine gel disclosed by the invention takes radix sophorae flavescentis, fructus cnidii, dandelion, scutellaria baicalensis and the like as core components, an efficient and mild gynecological inflammation treatment agent is developed, core traditional Chinese medicines are fused, and a biocompatible material is combined, so that quick effect taking and no side effect are ensured, and a better choice is provided for a patient.

The invention relates to the technical field of pharmaceutical preparations, and discloses muscle cooling powder for enhancing swelling caused by exosmosis of a CT (computed tomography) contrast agent and a preparation method thereof.The muscle cooling powder is prepared from amur corktree bark, coptis chinensis, scutellaria baicalensis, rheum officinale, frankincense extract and borneol as active ingredients, a natural deep-eutectic solvent (NADES) generated by reaction of choline chloride and glycerol as a functional solvent, and the skin cooling powder is prepared by mixing the active ingredients and the functional solvent. Polyvinyl alcohol and poloxamer 407 are combined to form a dual polymer matrix, and sodium tetraborate is used as a cross-linking agent. The preparation method comprises the steps of NADES preparation and ultrasonic drug loading, emulsification and solubilization, substrate solution dissolution and dynamic cross-linking molding. According to the invention, the solubility and the transdermal permeability of insoluble drugs are obviously improved through an NADES system; a dynamic boric acid ester bond cross-linked network constructed by boric acid radicals and polyol is utilized to endow the gel with excellent self-healing performance and tissue adhesive force, the problem that the dressing at the joint part is easy to fall off is effectively solved, the forming quality is uniform, and the physical stability is good.

The invention relates to a diamidine phenylurea dipropionate sustained-release emulsion for livestock and a preparation method thereof. Every 100g of the emulsion comprises the following components by weight: 0.1 to 4.0 g of diamidine phenylurea dipropionate, 6.0 to 10.0 g of olive oil, 4.0 to 8.0 g of span-80, 0.1 to 2.0 g of propylene glycol monostearate, 20.0 to 40.0 g of polyoxyethylene (60) castor oil, 0.1 to 0.3 g of sclerotium glucan, 0.01 to 0.1 g of glycerol, 0.01 to 0.2 g of trisodium phosphate and the balance of water. Meanwhile, the invention further discloses a preparation method, the process is easy to operate, production can be achieved through conventional equipment, and low-cost conversion and market popularization are facilitated. The sustained-release emulsion disclosed by the invention is in a water-in-oil-in-water (W / O / W) multiple emulsion form, and is good in needle passing property in clinical use, easy to absorb by tissues, small in local irritation and safe in clinical use. The emulsion has slow-release and long-acting characteristics, can reduce administration times, save manpower and material resource costs, and avoid strong animal stress response, and has good popularization and application values.

The present application belongs to the field of pharmaceutical preparations, and particularly relates to a gel of Duiyiwai and application thereof. The gel of Duiyiwai is an external preparation prepared from raw and auxiliary materials including the following parts: Duiyiwai extract 1.25-5 parts by weight, carbomer 940 0.5-1 part by weight, hydroxyphenyl ethyl ester 0.01-0.05 part by weight, triethanolamine 0.5-1 volume part, glycerol 1-2 volume parts, 1,2-propylene glycol 1.5-2 volume parts. The gel of Duiyiwai has the same curative effect as the Duiyiwai extract of the same dosage in repairing acute wounds; but has a significantly better curative effect than the Duiyiwai extract of the same dosage in repairing infected wounds, and is also better than the commonly used fuscide acid cream and compound Huangbai liquid in the clinic, and has practical popularization and application value.

This application relates to the field of pet food technology, specifically disclosing a pet health supplement, its preparation method, and its application. The pet health supplement, by weight, comprises the following raw material components: 60-90 parts hydrolyzed small molecule protein peptides; 0.1-1 part chicken egg-derived IgY antibody; 0.1-1 part natural organic acid; 1-5 parts glycerol; 0.1-1 part natural antioxidants; 0.5-5 parts prebiotics; 0-0.05 parts ε-polylysine; and 1-15 parts functional ingredients. The pet health supplement of this application can effectively reduce the risk of allergies in pets and people in contact with them, and is safe and non-toxic with good palatability and flavor, suitable for long-term feeding to pets.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to traditional Chinese medicine composition particles and an industrial preparation method thereof. The traditional Chinese medicine composition granules are prepared from the following medicinal raw materials in parts by mass: 580 to 640 parts of radix astragali seu hedysari, 350 to 400 parts of fried semen descurainiae, 350 to 400 parts of rhizoma chuanxiong, 200 to 260 parts of cassia twig processed by glycerol, 200 to 260 parts of salted rhizoma alismatis, 130 to 160 parts of radix platycodonis and 60 to 90 parts of fructus ziziphi jujubae. According to the technical scheme, a step-by-step extraction strategy that ligusticum wallichii and cassia twig are decocted together and then decocted with other medicinal materials is adopted, and the medicine effect is further guaranteed. According to the technical scheme, the technical problem that the content of key functional components such as ferulic acid, cinnamaldehyde and gentiobioside in a product in the prior art needs to be further increased can be solved. The technical scheme has outstanding industrialization advantages, takes cost and feasibility into account, and has clear clinical value and industrial prospect.

The invention relates to the technical field of perfume, in particular to perfume containing plant essential oil and a preparation method of the perfume. The perfume comprises the following components in percentage by mass: 20-50% of plant essential oil, 3-6% of a stabilizer, 5-12% of deionized water and the balance of absolute ethyl alcohol, wherein the plant essential oil is prepared from the following raw materials in parts by weight: 8-15 parts of mint leaves, 6-12 parts of cinnamomum camphora leaves, 5-12 parts of lemon grass, 3-8 parts of rosemary and 2-6 parts of maca flowers. The stabilizing agent composed of PEG-400 and glycerol is added into the perfume containing the plant essential oil, so that the perfume has the characteristics of lasting fragrance, good stability and high volatilization persistence.

The invention is suitable for the technical field of insect repellent drops, and provides a compound long-acting insect repellent drop and a preparation method thereof, the compound long-acting insect repellent drop comprises an active component, a micro-capsule component, a gel component and a proper amount of water, the mass concentration ratio of the active component to the micro-capsule component to a temperature-sensitive phase change component is (15-20): (22-27): (54-60); the active component comprises a main active component, fipronil and amitraz, and the mass concentration ratio of the main active component to fipronil to amitraz is (6-10): (1-3): (0.2-0.9); the microcapsule component comprises an inner core layer, the inner core layer comprises poly (glycerol sebacate) and polyhydroxybutyrate valerate, and the mass concentration ratio of the poly (glycerol sebacate) to the polyhydroxybutyrate valerate is (3-5): (2-5). According to the invention, the drug effect of the insect repellent drop is obviously prolonged to more than 3 months through a microencapsulation technology, the administration frequency is reduced, and meanwhile, the skin irritation is reduced.

The invention discloses a radix ranunculi ternati extract and a preparation method thereof. The radix ranunculi ternati extract is prepared from the following components: N-fructosyl isoleucine, N-fructosyl phenylalanine, N-linolenyl-4-aminobutyric acid, adenine, DL-arginine, 5-hydroxymethylfurfural, choline, cane sugar, adenosine, L-leucine, 1-palmitoyl-SN-glycerol-phosphorylcholine, N-linolenyl-4-aminobutyric acid, Boc-L-aspartic acid, sodium alginate, sodium alginate, sodium alginate and sodium alginate. Betaine and nicotinic acid. Compared with the prior art, the invention provides a brand new radix ranunculi ternati extract, the extract is extracted from a natural traditional Chinese medicine raw material radix ranunculi ternati, and the extract contains high-content active ingredients of amino acids, vitamins, nucleosides, saccharides and alkaloids, has multiple types of effective substances, and has a relatively high application value. And the preparation method is simple and worthy of further popularization.

This invention belongs to the field of skincare technology and discloses a tomato seed oil-based cream, its preparation method, and its application. The cream is made with a specific ratio of water, tomato seed oil, a composite emulsifier, and low, medium, and high molecular weight hyaluronic acid. The composite emulsifier consists of Tween 60, Tween 80, and glycerol, with glycerol possessing both emulsifying and moisturizing functions. The hyaluronic acid is compounded in a mass ratio of 2-5:2-4:3-6, with the molecular weight increasing progressively. The resulting cream exhibits good physical stability, forming a water-locking protective film on the skin surface after application, providing long-lasting moisturizing effects, and significantly inhibiting the oxidative degradation of unsaturated fatty acids in tomato seed oil. This invention is applicable to leave-on skincare products such as creams, lotions, and serums.