Composition for treating cold, preparation method and capsule
A composition and cold technology, applied in the directions of capsule delivery, drug combination, medical preparations containing active ingredients, etc., to achieve the effects of high efficiency, good use experience and low difficulty
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[0039] The present invention proposes a preparation method of a composition for treating colds, which mainly includes the following steps: after pulverizing raw materials except acetaminophen and chlorpheniramine maleate, decocting, and obtaining filtrate 1 after solid-liquid separation, After being concentrated, it is mixed with ethanol, and the filtrate 2 is obtained after separation, and then mixed with acetaminophen and chlorpheniramine maleate to prepare a composition.
[0040] Specifically, the raw materials except acetaminophen and chlorpheniramine maleate are pulverized to 80 mesh to 140 mesh, and then decocted. At this time, under the particle size conditions, using water as a solvent can effectively improve the extraction efficiency of active ingredients in traditional Chinese medicine raw materials, that is, to increase the diffusion degree and speed of active ingredients from raw material cell protoplasm to solvent water, so as to achieve the desired effect. When t...
Embodiment 1
[0046] The purpose of this example is to provide a composition for treating colds, including the following raw materials: 0.25g of paracetamol, 0.002g of chlorpheniramine maleate, 0.01g of artificial bezoar, 30g of notopterygium, 60g of ephedra, and 45g of cassia twig , Nepeta panicle 45g, Fangfeng 30g, Angelica dahurica 30g, Chuanxiong 30g, Shichangpu 15g, Pueraria 45g, Mint 15g, Bitter almond 60g, Angelica 30g, Scutellaria baicalensis 60g and Campanulaceae 30g.
[0047] The preparation method of this composition is as follows:
[0048] Crush the raw materials except acetaminophen and chlorpheniramine maleate to 100 meshes, decoct, obtain filtrate 1 after solid-liquid separation, concentrate 10 times, and mix with 95v / v% ethanol in a sealed environment Mix and stir for 100 minutes, centrifuge and precipitate to obtain a separation liquid 1, then mix 95v / v% ethanol with the separation liquid 1 in the same way for 50 minutes to obtain a separation liquid 2, and mix the separati...
Embodiment 2
[0050] The purpose of this example is to provide a composition for treating colds, including the following raw materials: 0.2g of acetaminophen, 0.0018g of chlorpheniramine maleate, 0.003g of artificial bezoar, 0.005g of caffeine, 15g of notopterygium, and ephedra 40g, Guizhi 25g, Nepeta panicle 20g, Fangfeng 15g, Angelica dahurica 10g, Chuanxiong 15g, Shichangpu 8g, Pueraria 30g, Mint 5g, Bitter almond 40g, Angelica 10g, Scutellaria baicalensis 40g and Campanulaceae 10g.
[0051] The preparation method of this composition is as follows:
[0052] Grind the raw materials except acetaminophen, caffeine and chlorpheniramine maleate to 80 mesh, decoct, obtain filtrate 1 after solid-liquid separation, concentrate 8 times, and mix with 75v / v% ethanol in Mix and stir for 60 minutes in a sealed environment, centrifuge and precipitate to obtain a separation liquid 1, and then mix and stir 75v / v% ethanol with the separation liquid 1 in the same manner for 40 minutes to obtain a separati...
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