Ear scaffold construction material and preparation process thereof

Abstract

The invention discloses an ear scaffold construction material and a preparation process thereof. The preparation process comprises the following steps: uniformly mixing soluble solid particles, medical liquid silicone rubber and an auxiliary agent, carrying out layered coating or perfusion on the mixture, placing a supporting core material on a surface of the mixture, continuing to coat or perfuse the mixture on a surface of the core material, and after curing and demolding, solvating out to remove solid particles to form a porous structure. A porous structure of the material can guide blood vessels to grow in, realize tight combination of an ear scaffold and tissues, and solve problems of scaffold exposure, soft tissue ulceration and the like in auricle reconstruction; the porous structure enables the silicone rubber to have flexibility matched with human tissues; and the supporting core material has enough strength to maintain a three-dimensional form for a long time. The material can be used for auricle reconstruction surgery after being subjected to personalized carving, trimming and sewing in the later period as an ear scaffold construction material.

Description

technical field [0001] The invention relates to an ear support construction material and a preparation method thereof, specifically belonging to the field of biomedical materials. Background technique [0002] Auricle reconstruction mainly involves the construction of ear brackets and the selection of skin and soft tissues covering the ear brackets. Materials currently used for ear supports include autologous costal cartilage, medical silicone rubber, and porous polyethylene. Autologous cartilage has long been the preferred material for stents because it does not cause immune rejection and rarely exposes the stent. However, the removal of autologous costal cartilage requires surgery, which increases the pain of patients; silicone stents have a high rate of exposure and tissue inflammation. The characteristic of high response limits its clinical application; porous polyethylene scaffold is a kind of artificial material that is widely used, and has good biocompatibility and s...

AI Technical Summary

Problems solved by technology

However, traditional methods of auricle reconstruction are prone to rupture of the soft tissue covering the stent and exposure of the stent to varying degrees. Analysis of the reasons for this is mainly due to the antigenicity of the porous polyethylene itself and the hard texture of the stent, which makes it insufficient. Flexible, not easy to withstand trauma, so the stent may be exposed

[0003] Chinese patent CN203183085 U ultra-thin porous silicone rubber ear bracket provides a way to make silicone rubber into an ultra-thin and porous form by changing the thickness of the silicone rubber At the same time, it has a complete structure of helix, anti-helix, and concha cavity to solve the risk of skin necrosis and bracket exposure due to pressure, but the ultra-thin and porous structure of this patent will reduce the support strength of the bracket, and if the strength is too low, it will be difficult. Maintain the three-dimensional shape of the auricle for a long time and affect the effect of implantation

This method only changes the traditional manufacturing method to three-dimensional modeling, two-dimensional layered stacking or layered cutting in the molding process, without substantial changes to the structure and properties of the material itself, and the strength and elasticity of the final product cannot be fully realized. ensure

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