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Application of antrodia camphorata in dispelling effects of alcohol and/or increasing alcohol metabolism

A technology of Antrodia cinnamomea and mycelium of Antrodia cinnamomea, applied in the field of hangover and/or increasing alcohol metabolism, Antrodia cinnamomea, can solve the problems of increasing the risk of metabolic syndrome, increasing uric acid and lactic acid content, and low mobility, etc., to achieve increased Effects on hangover efficiency, promotion of alcohol decomposition, and reduction of oxidative stress

Pending Publication Date: 2021-10-12
GREENYN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Generally speaking, moderate intake of alcohol can relax people, but when excessive intake of alcohol, it will cause discomfort such as dizziness, vomiting, poor cognitive ability, nausea, and low mobility, which may continue to affect the next day's life , in the long run, it will also have adverse effects on health
There are currently many products on the market that appeal to hangover effects, such as increasing the metabolism of alcohol through the intake of fructose. However, using fructose to increase the rate of alcohol metabolism will not only lead to an increase in uric acid and lactic acid levels, but also increase the risk of metabolic syndrome

Method used

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  • Application of antrodia camphorata in dispelling effects of alcohol and/or increasing alcohol metabolism
  • Application of antrodia camphorata in dispelling effects of alcohol and/or increasing alcohol metabolism
  • Application of antrodia camphorata in dispelling effects of alcohol and/or increasing alcohol metabolism

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0042] Example 1: Sample Preparation

[0043] Sample 1: Antrodia Antrodia water-soluble powder, wherein, Antrodia Antrodia water-soluble powder is a powdery extract obtained by emulsifying and drying the mycelia powder of Antrodia Antrodia through supercritical carbon dioxide extraction, and after testing, it is confirmed that it contains the same content as wild Antrodia Antrodia content of triterpenoids.

[0044] For example, the mycelium powder of Antrodia camphorata is subjected to supercritical carbon dioxide extraction, and then concentrated to obtain the super-extract of mycelium of Antrodia camphorata in paste form. The weight ratio of 1:6-7 is mixed at a temperature of 70° C. to obtain an oil phase solution of Antrodia camphorata. Prepare an aqueous phase solution, which contains water, dextrin fiber, and fatty acid sucrose lipid, and mixes them at a weight ratio of about 357-358:72:1. Antrodia camphorata oil phase solution and water phase solution are microemulsifi...

example 2

[0047] Example 2: Preliminary test

[0048] 3 groups of mice were administered intragastrically with 0.3mL / 20g, 0.35mL / 20g, 0.4mL / 20g alcohol solution (58% Jinmen sorghum) respectively, with 8 mice in each group, to observe whether the mice in each group appeared to turn over. Lost of righting reflex (LOR) and no amount of alcohol required for death of mice.

[0049] It was found that a small number of mice died when 0.4mL / 20g alcohol solution was given; no mice died when 0.35mL / 20g alcohol solution was given, the drunk rate was 100%, and the average drunk time was 794.0 ± 38.02 minutes; No mice died when the alcohol solution was 1 / 20g, and the drunk rate was 25%; therefore, in the follow-up hangover test, the mice were gavaged with 0.35mL / 20g alcohol solution.

example 3

[0050] Example 3: hangover test (1)

[0051] Mice were randomized into groups where:

[0052] The first group is the blank group, fed with equal volume of normal saline;

[0053] The second group is the low-dose group of Antrodia cinnamomea water-soluble powder, and the dosage is 16.3 mg / kg;

[0054] The third group is the medium-dose group of Antrodia antrodia water-soluble powder, and the dosage is 32.8mg / kg;

[0055] The fourth group is the high-dose Antrodia Cinnamomea water-soluble powder group, and the dosage is 49.2 mg / kg;

[0056] The fifth group is Hovenia dulcis Function Decoction group, and the dosage is 3.38g / kg;

[0057] The sixth group patent Hovenia dulcis fruit extract group, the dosage is 504.3mg / kg;

[0058] The seventh group was the mixed group, which was administered Hovenia dulcis Function Drink (dose 3.38g / kg) and Antrodia camphorata water-soluble powder (dose 16.3mg / kg) at the same time.

[0059] The mice in each group were fasted for 12 hours first...

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Abstract

The invention provides an application of antrodia camphorata powder in preparation of an anti-alcoholism composition. By administration of an effective amount of the antrodia camphorata powder to an individual, metabolism of alcohol and / or acetaldehyde in the individual can be accelerated, so that the content of alcohol and / or acetaldehyde in blood is reduced. Besides, the drunkenness reaction time of the individual is shortened, so that the effect of dispelling the effects of alcohol is achieved.

Description

technical field [0001] The present invention relates to the second use of Antrodia cintrodia, in particular to the use of Antrodia cintrodia for relieving hangover and / or increasing alcohol metabolism. Background technique [0002] Antrodia camphorata (Taiwanofunguscamphoratus), commonly known as Antrodia camphorata, also known as camphor mushroom, camphor mushroom, Kunei mushroom, and Shenming mushroom, is a medicinal fungus, a species of Antrodia in the family Fomitopsidaceae. Fungus, only native to Taiwan. The medicinal physiological activities of Antrodia antrodia are very extensive and significant. At least 78 species have been isolated and identified, of which 39 are triterpenoids, and 31 have their chemical structures determined. The compounds contained in Antrodia camphorata can be roughly classified into polysaccharides, triterpenes and sterols, benzenes, benzoquinone derivatives, maleic acid ) and succinic acid (Succinic acid) derivatives, etc.; and according to ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/07A61P39/00A61P39/02
CPCA61K36/07A61P39/00A61P39/02A61P25/32A61K9/0095A61K9/19A61K9/1075A61K47/26A61K47/36A61K2236/00A23L33/10A23L31/00A61K36/06A61P1/16A23V2002/00A23V2200/334A61K9/0053
Inventor 徐榜奎吴嘉峰
Owner GREENYN BIOTECH
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