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External medicine composition for promoting hair growth and preparation method and application

A technology of external medicine and composition, which is applied in the field of traditional Chinese medicine composition for promoting hair growth, and can solve problems such as dementia, decreased libido, and contact dermatitis

Inactive Publication Date: 2021-12-21
河北省中医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Aiming at the understanding and standardized treatment of androgenetic alopecia, the "Guidelines for the Diagnosis and Treatment of Androgenetic Alopecia in China (2014 Edition)" edited by the Chinese Medical Association made a detailed description of the relevant clinical manifestations, pathogenesis, classification diagnosis and drug treatment. Relevant explanations, treatment methods mainly include internal medicine, external medicine and hair transplantation, etc. Combined treatment is recommended to obtain the most ideal effect; currently clinical male patients mainly take finasteride tablets orally, but because of the side effects caused There are relatively many side effects, especially the side effects of decreased libido, which are unacceptable to many patients; oral spironolactone and other drugs for female patients also have side effects such as breast distending pain; externally used drugs are minoxidil tincture, which may cause body hair increase and exposure Sexual dermatitis, and even "crazy shedding period"; traditional Chinese medicine believes that androgenetic alopecia is related to kidney, spleen, liver, lung, heart, qi and blood, etc. Clinical research has been carried out through theoretical dialectics, and many related facts have been summarized Oral Chinese medicine treatment drugs and empirical prescriptions have achieved corresponding technical effects, but due to the particularity of oral Chinese medicine, patients' compliance and acceptance are poor, so the applicant based on Chinese medicine compositions and many years of clinical experience in androgenetic alopecia, based on Utilizing the dialectical thinking of traditional Chinese medicine, develop a Chinese medicine composition for external use of hair growth and related hair growth tincture products

Method used

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  • External medicine composition for promoting hair growth and preparation method and application
  • External medicine composition for promoting hair growth and preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] An external medicinal composition for promoting hair growth, which consists of 5 parts by weight of Cordyceps sinensis, 5 parts of ginseng, 5 parts of astragalus, 4 parts of black sesame, 15 parts of licorice, 15 parts of oriental cypress leaves, and 4 parts of Sophora flavescens;

[0036] The Cordyceps sinensis, ginseng, astragalus, black sesame, licorice, arborvitae leaves and flavescens that have been screened in parts by weight are pulverized and passed through a 50-100 mesh sieve for subsequent use;

[0037] Mix the pulverized pharmaceutical composition evenly, and add 80% ethanol to carry out reflux extraction for 3 times to obtain a reflux liquid;

[0038] Leave the reflux liquid to stand and filter for 2 hours to obtain the filtrate, and then obtain a thick paste composition extract by concentrating the filtrate;

[0039] The ethanol content of the extract of the thick paste composition is not less than 30%.

Embodiment 2

[0041] An external medicinal composition for promoting hair growth consists of 8 parts by weight of cordyceps sinensis, 8 parts of ginseng, 4 parts of astragalus, 6 parts of black sesame, 12 parts of licorice, 16 parts of arborvitae leaves and 5 parts of sophora flavescens.

[0042] The Cordyceps sinensis, ginseng, astragalus, black sesame, licorice, arborvitae leaves, and sophora flavescens screened in parts by weight are pulverized and passed through a 50-100 mesh sieve for subsequent use;

[0043] Mix the pulverized pharmaceutical composition evenly, and add 95% ethanol to carry out reflux extraction twice to obtain a reflux liquid;

[0044] Leave the reflux liquid to stand and filter for 2 hours to obtain the filtrate, and then obtain a thick paste composition extract by concentrating the filtrate;

[0045] The ethanol content of the extract of the thick paste composition is not less than 30%.

[0046] In the embodiment of the present invention, the pharmaceutical composi...

Embodiment 3

[0050] A hair growth tincture, comprising the extract of the above-mentioned thick paste composition, and 2-5 times the amount of ethanol; the hair growth tincture is prepared from the two to obtain a liquid preparation;

[0051] The prepared thick paste composition extract contains more than 30% ethanol, which is fully dissolved. In order to obtain a hair growth tincture with higher dissolution and absorption efficiency, 2-5 times the amount of ethanol is used to dissolve it to obtain a hair growth tincture. Applying the tincture to the affected area can be combined with other physical therapy, and the effect is remarkable.

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Abstract

The invention discloses an external medicine composition for promoting hair growth and a preparation method and application. The external medicine composition is based on the dialectical thought of traditional Chinese medicine and is prepared from pure traditional Chinese medicine. The external medicine composition for promoting hair growth is prepared from cordyceps sinensis, ginseng, milkvetch roots, black sesame, licorice roots, cacumen biotae and radix sophorae flavescentis. The external medicine composition is blended with ethyl alcohol to be externally applied to the diseased part, and the obtained tincture has the remarkable hair growth effect under the synergistic effect of the raw materials cordyceps sinensis, ginseng, milkvetch roots, black sesame, licorice roots, cacumen biotae and radix sophorae flavescentis; and meanwhile, the hair growth tincture is blended with ethyl alcohol, the characteristics of ethyl alcohol are utilized, the ingredients of the medicine composition are subjected to the particle medicine carrying principle, the transdermal effect of the effective ingredients is remarkable, the grease form of the skin is changed, the permeation efficiency of the active ingredients is improved, the transdermal amount of the active ingredients is increased while the skin grease is reduced, the good transdermal effect is achieved, and the purpose of promoting hair growth is achieved; the patient acceptance degree and satisfaction degree are high.

Description

technical field [0001] The invention relates to an external pharmaceutical composition for promoting hair growth, a preparation method and application thereof, and relates to the technical field of traditional Chinese medicine compositions for promoting hair growth. Background technique [0002] Androgenic alopecia (AGA) is the most common type of hair loss. It is a hair loss disease with progressive miniaturization of hair follicles that begins at puberty or late adolescence. The hair thinning category is mainly caused by the shortening of the growth period in the hair growth cycle and the miniaturization of hair follicles. The clinical manifestation is the transformation of terminal hair into vellus hair. The course of the disease is long and stubborn. It is also one of the refractory diseases; [0003] Aiming at the understanding and standardized treatment of androgenetic alopecia, the "Guidelines for the Diagnosis and Treatment of Androgenetic Alopecia in China (2014 Ed...

Claims

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Application Information

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IPC IPC(8): A61K36/489A61K9/08A61P17/14
CPCA61K36/068A61K36/258A61K36/481A61K36/185A61K36/484A61K36/14A61K36/489A61K9/0014A61K9/08A61P17/14A61K2236/333A61K2300/00
Inventor 刘湘丁红炜王淑惠尹晓华云璐陈贵婧申桦桂建朝
Owner 河北省中医院
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