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Hydroxyapatite nanoparticles as well as preparation method and defluorination application thereof

A hydroxyapatite and nanoparticle technology, applied in the field of materials, can solve the problems of high specific surface area materials, such as high price, secondary pollution, and inability to use on a large scale, and achieves excellent suspension stability, small particle size, good The effect of the application foreground

Pending Publication Date: 2022-07-22
CCTEG CHINA COAL RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The disadvantage of this method is that materials with high specific surface area such as graphene and carbon nanotubes are expensive and cannot be used on a large scale
[0006] The second is to use metal ion doping, by constructing crystal defects, using one or more of calcium, magnesium, aluminum, cerium, lanthanum, iron and other ions to replace part of the calcium ions, and by combining with F - Form a coordination effect to improve the effect of fluorine removal; the disadvantage of this direction is that a large amount of miscellaneous ions will be introduced into the effluent, causing secondary pollution, and the price of some rare earth ions will also affect the cost of water treatment

Method used

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  • Hydroxyapatite nanoparticles as well as preparation method and defluorination application thereof
  • Hydroxyapatite nanoparticles as well as preparation method and defluorination application thereof
  • Hydroxyapatite nanoparticles as well as preparation method and defluorination application thereof

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preparation example Construction

[0055] The preparation method of hydroxyapatite nanoparticles according to the embodiment of the present invention includes the following steps:

[0056] (1) Dissolving soluble phosphate in water to obtain phosphorus salt solution:

[0057] (2) dissolving the soluble calcium salt in water to obtain a calcium salt solution;

[0058] (3) adding citric acid to the calcium salt solution, after mixing and stirring, drip the phosphorus salt solution, after the dropping is completed, adjust the pH of the mixed solution to be alkaline to obtain an alkaline mixed solution;

[0059] (4) After synthesizing the product by using the alkaline mixed solution as the precursor solution, centrifuging and drying the hydroxyapatite nanoparticles.

[0060] In the embodiment of the present invention, in order to solve the problem that the crystals of the hydroxyapatite nanoparticles are easy to agglomerate in the related art, the embodiment of the present invention utilizes the special structure o...

Embodiment 1

[0089] In this example, Ca(NO 3 ) 2 ·4H 2 O and (NH 4 ) 2 HPO 4 Hydroxyapatite nanoparticles were prepared by preparing a precursor solution for hydrothermal reaction synthesis. Specifically:

[0090] A preparation method of hydroxyapatite nanoparticles, comprising the following steps:

[0091] (1) will (NH 4 ) 2 HPO 4 Dissolve in water to obtain a solution of phosphorus salts: PO 4 3+ The concentration of 0.15mol / L;

[0092] (2) Ca(NO) 3 ) 2 ·4H 2 O is dissolved in water to obtain a calcium salt solution, Ca 2+ The concentration of 0.25mol / L;

[0093] (3) Take 100 mL of calcium salt solution, add 0.02 g of citric acid solid under stirring at 800 rpm, add 100 mL of phosphate salt solution dropwise after stirring for 10 minutes, and the dropping rate is 1.0 mL / min. The pH was adjusted to 10.0 with mol / L sodium hydroxide solution. After the pH of the system was stabilized, stirring was continued for 1 h under sealed conditions, and finally the precursor solutio...

Embodiment 2

[0095] In this example, Ca(NO 3 ) 2 ·4H 2 O and (NH 4 ) 2 HPO 4 Preparation of precursor solution for chemical precipitation synthesis to prepare hydroxyapatite nanoparticles. Specifically:

[0096] A preparation method of hydroxyapatite nanoparticles, comprising the following steps:

[0097] (1) will (NH 4 ) 2 HPO 4 Dissolve in water to obtain a solution of phosphorus salts: PO 4 3+ The concentration of 0.15mol / L;

[0098] (2) Ca(NO) 3 ) 2 ·4H 2 O is dissolved in water to obtain a calcium salt solution, Ca 2+ The concentration of 0.25mol / L;

[0099] (3) Take 100mL calcium salt solution, add citric acid solid under the stirring condition of 700rpm, after stirring for 10 minutes, add 100mL phosphorus salt solution dropwise, the dripping rate is 1.2mL / min, after the dropwise addition, use 1.0mol / min L of sodium hydroxide solution to adjust the pH to 10.0. After the pH of the system was stabilized, stirring was continued for 1 h under sealing conditions, and the...

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Abstract

The invention discloses a hydroxyapatite nano-particle and a preparation method and defluorination application thereof, the preparation method of the hydroxyapatite nano-particle comprises the following steps: (1) dissolving soluble phosphate with water to prepare a phosphorus salt solution: (2) dissolving soluble calcium salt with water to prepare a calcium salt solution; (3) adding citric acid into the calcium salt solution, mixing and stirring, dropwise adding a phosphorus salt solution, and after dropwise adding, adjusting the pH value of the mixed solution to be alkaline to obtain an alkaline mixed solution; and (4) synthesizing a product by taking the alkaline mixed solution as a precursor solution, centrifuging, and drying to obtain the hydroxyapatite nano-particles. According to the method, the crystal development and agglomeration degree of the hydroxyapatite are regulated and controlled through different adsorption acting forces of citric acid and different crystal faces of the hydroxyapatite, and the synthesized hydroxyapatite nanoparticles are small in particle size, can be quickly dispersed in water and have better suspension stability.

Description

technical field [0001] The invention belongs to the technical field of materials, and in particular relates to a spherical hydroxyapatite nanoparticle, a preparation method thereof, and an application thereof in the field of inorganic fluoride ion removal. Background technique [0002] Hydroxyapatite (Ca 10 (PO 4 ) 6 (OH) 2 , referred to as HAP) is an extremely versatile bioceramic material, because it is consistent with the composition of human teeth and bones, it is often used as a carrier for bone tissue repair materials and targeted drugs. In the field of medicine and biomaterials, nano-hydroxyapatite can be used as a gene carrier for gene therapy. In order to solve the problem of easy agglomeration of nano-hydroxyapatite crystals, Li Wo et al. used CTAB, PEG2000 and human serum for hydrothermal synthesis. Compared with the other two surfactant complexes, the hydroxyapatite nanoparticles modified on the surface of CTAB have better dispersion and suspension stability,...

Claims

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Application Information

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IPC IPC(8): C01B25/32B01J20/30B01J20/04B82Y40/00
CPCC01B25/325B01J20/30B01J20/048B82Y40/00C01P2004/03C01P2004/32C01P2004/64
Inventor 李文博赵佳昕陈贵锋刘敏王晓磊
Owner CCTEG CHINA COAL RES INST