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Agastache capsule for restoring healthy energy andits prepn and application

A Huoxiangzhengqi and capsule technology, which is applied in capsule delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of gastrointestinal irritation, discomfort, and influence on curative effect, etc.

Inactive Publication Date: 2004-09-08
JIANGXI HERBFINE HI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantages of a large amount of ethanol, in addition to increasing the cost of the product, are that it stimulates the gastrointestinal tract greatly, often feels uncomfortable after taking it, and even causes vomiting, which is not easy for patients to accept and affects the normal performance of the curative effect. range is also limited

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] According to the raw materials and dosage ratio stipulated in "Huoxiang Zhengqi Water" on page 633 (2000 edition) of "Pharmacopoeia of the People's Republic of China", take 160g of Atractylodes Rhizome, 240g of Angelica dahurica, 160g of Tangerine Peel, 160g of Magnolia officinalis (Ginger), 240g of Poria cocos, and 240g, raw pinellia 160g, licorice extract 20g, patchouli oil 1.6ml, perilla leaf oil 0.8ml. Each crude drug raw material is subjected to conventional pretreatment and appropriate pulverization. Atractylodes atractylodis, tangerine peel, Magnolia officinalis and Angelica dahurica were mixed first, and 5 times the weight of water was added, heated to reflux for 0.5 hours, and the volatile oil was collected by steam distillation for later use. The residual mother liquor and dregs after distillation are mixed with Dabupi and Poria cocos, add water and decoct at least twice, each time for 1-2 hours, each decoction is combined, filtered and properly concentrated, ...

Embodiment 2

[0052] Raw materials and consumption are the same as example 1. The amount of water added during reflux was 7 times the weight of the raw material, and after 1 hour of reflux, the volatile oil was collected by steam distillation. The rest of the operations are the same as Example 1.

Embodiment 3

[0054] Raw materials and consumption are the same as example 1. The amount of water added during reflux is 10 times the weight of the raw material, and after reflux for 2 hours, the volatile oil is collected by steam distillation for subsequent use. The remaining water decoction operations are the same as in Example 1. After various decoctions are mixed with licorice extract, ultrafiltration is carried out with a polyalum hollow fiber ultrafiltration membrane with a cut-off flow rate of 50,000 molecules to remove macromolecular organic impurities to obtain a clear medicinal solution. All the other mixing preparation operations are the same as Example 1.

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PUM

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Abstract

The present invention is double-phase agastache hard capsule filled with separate liquid component and solid component and its preparation and application. During its preparation, the materials in certain proportion are extracted to obtain volatile oil; the volatile oil is produced into dripping pill or soft capsule; the residue after extracting volatile oil and other materials are prepared into granule through conventional decoction, alcohol precipitation or ultrafiltering, eliminating cellulose, gum and other macromolecular impurities, concentration, drying and pelletizing; capsulizing the granule and dripping pill or soft capsule to form hard capsule, and packing. The said packing method can reduce the volatilization of the volatile oil, reduce the chemical and physical changes of the components owing to mixing, reduce needed supplementary material and thus reduce cost and taken quantity.

Description

technical field [0001] The invention relates to an oral preparation prepared from extracts of traditional Chinese medicine plants, in particular to Huoxiangzhengqi dual-phase capsules filled with liquid components and solid components, and a preparation method and application thereof. Background technique [0002] Huoxiang Zhengqi Chinese patent medicines are commonly used medicines that relieve exterior and dampness, regulate qi and harmonize neutralization, and also have antibacterial and antiviral functions. Among them, the capsule dosage form with quick curative effect and convenient administration is more popular. One of the previous capsule preparations is to mix the aromatic volatile components extracted from raw materials with water-soluble components to make soft capsules. Due to the mixing of volatile oil components and water-soluble components, chemical changes may occur, and it is also necessary to use solubilizers to improve cost. The other is "Huoxiang Zhengqi...

Claims

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Application Information

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IPC IPC(8): A61K9/48A61P1/12A61P1/14A61P25/04A61P31/00
Inventor 吕爱平罗晓健龚建平
Owner JIANGXI HERBFINE HI TECH
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