The invention discloses a preparation method of an oyster and eucommia ulmoides male flower cream, and the oyster and eucommia ulmoides male flower cream comprises the following raw materials: fructo-oligosaccharide, Chinese yams, fructus lycii, a longan pulp, rhizoma polygonati, fructus alpiniae oxyphyllae, red yeast rice, ginseng, oyster, eucommia ulmoides male flower, penis et testis cervi, hawthorn, mulberries, orange peels and colla corii asini. The formula takes the fructo-oligosaccharide as a matrix to prepare the cream, the excessively high sugar content of a finished product of the male flower cream is avoided, the overall heat of the product is reduced, a user is prevented from getting fat, the product is healthier, the oyster is used to tranquilize liver and yang, induce astringency, soften hard lumps and dispel nodes, meanwhile, the oyster contains more calcium carbonate, calcium phosphate, calcium sulfate, organic materials and the like, the immunity is enhanced to inhibitthe growth of a tumor, the eucommia ulmoides male flower is added, contains more ingredients like zinc, selenium and Vitamin B, can tranquilize and soothe the nerves, and effectively improves the sleeping quality of people, a flavonoid compound in the eucommia ulmoides male flower can nourish the skin and accelerate the metabolism of a body, moreover, the natural active ingredient of the eucommiaulmoides male flower can protect the liver.