Derivative of substitutional taurine and preparation method
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- PEKING UNIV
- Publication Date
- 2005-11-16
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
Technical field:
[0001] The invention belongs to the technical field of organic compounds and organic synthesis, and specifically relates to a new class of substituted taurine derivatives and a preparation method thereof. Background technique:
[0002] Sulfamic acid, as an important analogue of a class of natural amino acids with a tetrahedral structure, has attracted much attention in recent years (Xu Jiaxi, Organic Chemistry, 2003, 23, 1). β-Sulfamic acid can be regarded as a substituted taurine, and it is also an important raw material and monomer for the synthesis of sulfonyl peptides. Taurine is a class of molecules with important biological functions (Liebowitz, S.M.; Lombardini, J.B.; Salva, P.S. Biochem. Pharmac. 1988, 37, 1303), is also a class of important nutrients, widely used as food additives and so on. Research on the biological function of sulfamic acid has found that some sulfamic acid has anticancer and antiviral activity (Neelakantan, L.; Hartung, W.H.J.O...