Method for prenaring spherical hydroxy-apatite nano crystal

A technology of hydroxyapatite and nanocrystals, which can be used in chemical instruments and methods, phosphorus compounds, inorganic chemistry, etc., and can solve the problems that the preparation method of spherical HAp crystals has not been reported.
CN1821061AInactive Publication Date: 2006-08-23FUJIAN NORMAL UNIV
0 Cites 21 Cited by

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
FUJIAN NORMAL UNIV
Publication Date
2006-08-23
Estimated Expiration
Not applicable · inactive patent
Patent Text Reader

Abstract

The process of preparing spherical nanometer hydroxyapatite crystal in water solution features that spherical nanometer hydroxyapatite crystal is synthesized with water soluble polymer PVP as template and through a biomineralization process. The process includes: spreading Ca(NO3)2íñ4H2O powder in the bottom of container A, preading (NH4)3PO4íñ3H2O powder in the weight ratio to Ca(NO3)2íñ4H2O of 1 to 1.67 in the bottom of container B, setting the container B inside the container B, slowly adding PVP aqua of pH 10.5 and concentration 0.02-2 wt% along in inner walls of the two containers to Ca(NO3)2íñ4H2O concentration of 0.01-0.20 mol / L and (NH4)3PO4íñ3H2O concentration of 0.006-0.12 mol / L and the solution overflow through the edge of the container B, stilling at 25 deg.c for 7 days to obtain precipitate, washing the precipitate, sucking filtering and drying to obtain the spherical nanometer hydroxyapatite crystal product. Altering the PVP concentration can regulate the crystal size in 15-150 nm.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to a method for preparing spherical hydroxyapatite nanocrystals in aqueous solution. technical background

[0002] Hydroxyapatite [Ca 10 (PO 4 ) 6 (OH) 2 , Hydroxyapatite, HAp for short] is the main inorganic component of human bones and teeth. The synthetic HAp has good biocompatibility, bioactivity and osteoconductivity, and is an excellent hard tissue replacement material. In recent years, with the rapid development of nano-HAp material research, people have a further understanding of the characteristics of HAp, such as nano-HAp can inhibit a variety of cancer cells, but has no effect on normal cells, or can be used as a drug for HIV virus growth Carrier, or liquid chromatography separation agent used to separate various biomolecules, etc. The synthesis methods of nano-HAp mainly include chemical precipitation method, hydrothermal reaction method, sol-gel method self-combustion method and microemulsion method, etc. Usually...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More