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Medicinal composition with dauricine and houttuynin sodium

A technology for houttuyniacin and composition, which is applied in the field of medicine and achieves the effects of exact curative effect, simple preparation process and good stability

Inactive Publication Date: 2007-04-04
海安江理工技术转移中心有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it has not been reported yet to prepare anti-infection, anti-inflammation, antipyretic, analgesic, etc. drugs by using the interaction between the root or its extract and neohouttuyniatin sodium, and combining prescriptions.

Method used

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  • Medicinal composition with dauricine and houttuynin sodium

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0092] Example 1 Preparation, Identification and Content Determination of Northern Bean Root Extract

[0093] Preparation of pea root extract

[0094] Take 10 kg of bean root, crush it into coarse powder, add 8 times the amount of sulfuric acid aqueous solution (pH1~2), warm soak (55~60°C) twice, each time for 24 hours, filter, combine the filtrates, let stand, After the precipitation is complete, take the supernatant and add carbonic acid to adjust the pH value to 9, let it stand until the precipitation is complete, discard the supernatant, take the precipitate and filter it with suction, wash with a small amount of water until neutral, and dry at 50-60°C to obtain the product.

[0095] Prepare three batches of bean root extract respectively, and the yields are shown in Table 2-1.

[0096] Identification of Bean Root Extract

[0097] Take 0.1g of bean root extract, grind finely, add 10ml of ethyl acetate, shake for 30 minutes, let it stand, take the supernatant as the test ...

Embodiment 2

[0103] The preparation of embodiment 2 BXY injection

[0104] 1. Prescription:

[0105] Prescription 1

[0106] Northern bean root extract 242g (equivalent to 24000g of raw medicinal materials)

[0107] New Houttuyniatin Sodium 8g

[0108] Polysorbate 80 50g

[0109] Add water for injection to 5000ml

[0110] A total of 1000 sticks were prepared

[0111] Prescription 2

[0112] Northern bean root extract 242g (equivalent to 24000g of raw medicinal materials)

[0113] New Houttuyniatin Sodium 4g

[0114] Polysorbate 80 50g

[0115] Add water for injection to 5000ml

[0116] A total of 1000 sticks were prepared

[0117] Prescription 3

[0118] Northern bean root extract 242g (equivalent to 24000g of raw medicinal materials)

[0119] New Houttuyniatin Sodium 40g

[0120] Polysorbate 80 60g

[0121] Add water for injection to 5000ml

[0122] A total of 1000 sticks were prepared

[0123] 2. Specific steps:

[0124] (1) Dispose of the pipes and containers used for l...

Embodiment 3

[0135] Example 3 Preparation of BXY for Injection

[0136] 1. Prescription:

[0137] Prescription 1

[0138] Northern bean root extract 236g (equivalent to 24000g of raw medicinal materials)

[0139] New Houttuyniatin Sodium 8g

[0140] Polysorbate 80 50g

[0141] Mannitol 300g

[0142] Add sterile water for injection to 3000ml

[0143] A total of 1000 sticks were prepared

[0144] Prescription 2

[0145] Northern bean root extract 118g (equivalent to 12000g of raw medicinal materials)

[0146] New Houttuyniatin Sodium 8g

[0147] Polysorbate 80 25g

[0148] Mannitol 300g

[0149] Add sterile water for injection to 3000ml

[0150] A total of 1000 sticks were prepared

[0151] Prescription 3

[0152] Northern bean root extract 490g (equivalent to 50000g of raw medicinal materials)

[0153] New Houttuyniatin Sodium 8g

[0154] Polysorbate 80 100g

[0155] Mannitol 300g

[0156] Add sterile water for injection to 3000ml

[0157] A total of 1000 sticks were prepare...

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Abstract

A Chinese medicine in the form of injection of any orally taken form for treating the infection of respiratory tract and digestive system, improving immunity, and preventing tumor is proportionally prepared from Asiatic moonseed rhizome or its extract and the sodium neohouttuyfonate or its pharmacologically acceptable salt.

Description

1. Technical field [0001] The invention relates to a pharmaceutical composition made from pedicel root or its extract, neohouttuyonin or a pharmaceutically acceptable salt thereof, a preparation method and application thereof, and belongs to the technical field of medicine. 2. Background technology [0002] Infectious diseases are diseases caused by viruses, mycoplasma, chlamydia, rickettsia, bacteria, fungi, parasites, etc. It is one of the major clinical diseases and seriously endangers human life and health. The emergence and application of antibiotics have played a huge role in the prevention and treatment of infectious diseases, but at the same time, the abuse of antibiotics has also led to the emergence of a large number of multi-drug resistant strains, and more and more refractory infections. Compared with antibiotics, many traditional Chinese medicine preparations have better clinical efficacy and less toxic and side effects. Under the severe situation that human bei...

Claims

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Application Information

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IPC IPC(8): A61K36/59A61P29/00A61P31/00A61P37/02A61P11/00A61P1/00A61K31/185
Inventor 蔡军
Owner 海安江理工技术转移中心有限公司
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