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Medicinal composition

A composition and drug technology, applied in the field of medicine, to achieve the effects of improved drug efficacy, less impurities, and uniform and stable drug quality

Inactive Publication Date: 2007-04-04
海安江理工技术转移中心有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Moreover, there is no report on the use of the interaction of new houttuyfonate sodium and jinguola to prepare prescriptions with antibacterial, antiviral, anti-inflammatory and antipyretic properties.

Method used

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  • Medicinal composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0151] The preparation of embodiment 1 golden fruit extract

[0152] Take 100kg of Lavender oleracea medicinal material, crush it into coarse powder, reflux extraction with 70% ethanol twice, each time for 2 hours, filter, recover ethanol from the filtrate until it has no alcohol smell, add water to adjust the total amount of the concentrated solution to 100L, add concentrated hydrochloric acid to adjust the pH value to 1 to 2, stir, filter, the filtrate passes through the treated strong acid cation exchange resin, wash with water until the eluent is neutral, dry the resin, add an appropriate amount of concentrated ammonia test solution to moisten, ethanol Reflux for extraction for 5 hours, recover ethanol from the ethanol solution, and vacuum-dry to obtain the extract of Lavender.

[0153] Assay

[0154] Determination of total alkaloid content

[0155] Take 0.1g of this product, weigh it accurately, put it in a stoppered Erlenmeyer flask, add 20ml of methanol, ultrasonicate...

Embodiment 2

[0163] Embodiment 2 Preparation of the composition powder injection of the present invention

[0164] prescription:

[0165] Yanhuning 40.0g

[0166] Golden Fruit Lam Extract 27.6g (Equivalent to 3000g Golden Fruit Lam Raw)

[0167] Polysorbate 80 30.0g

[0168] Mannitol 300.0g

[0169] Add sterile water for injection to 5000ml

[0170] A total of 1000 sticks were prepared

[0171] Preparation Process:

[0172] 1) First, aseptically treat the containers used for liquid preparation, antibiotic glass bottles, rubber stoppers, etc.

[0173] 2) Weigh the raw materials and auxiliary materials according to the prescription quantity.

[0174] 3) Add Yanhuning into 30% sterile water for injection and heat to dissolve completely. Mannitol is added with 30% of sterile water for injection, heated and stirred to dissolve completely, polysorbate 80 is added with 20% of sterile water for injection to make an aqueous solution, added wit...

Embodiment 3

[0182] Example 3 Preparation of the composition aqueous injection of the present invention

[0183] prescription:

[0184] Yanhuning 40.0g

[0185] Golden Fruit Lam Extract 27.6g (Equivalent to 3000g Golden Fruit Lam Raw)

[0186] Propylene glycol 700ml

[0187] Add water for injection to 5000ml

[0188] A total of 1000 sticks were prepared

[0189] Preparation Process:

[0190] 1) Dispose of the pipes and containers used for liquid preparation one day in advance, and rinse them with fresh water for injection before use.

[0191] 2) Add Yanhuning into water for injection with a dosing volume of 20%, heat and stir to dissolve completely. Add the extract of Aurea oleracea to propylene glycol, heat and stir to dissolve completely.

[0192] 3) Combine the above two solutions, and add water for injection to the full amount.

[0193] 4) Add activated carbon for needles with a dosing volume of 0.1%, heat and stir for 15 minutes.

[019...

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Abstract

An anti-infective and antiviral Chinese medicine for treating upper respiratory tract infection is proportionally prepared from 14-dehydroxy-11,12-didehydro andrographolide-3,19-semiester succinate and hairystalk tinospora root or its extract.

Description

1. Technical field [0001] The invention relates to a pharmaceutical composition with anti-infection, anti-virus and antipyretic effects, in particular to a composition mainly composed of water-soluble 14-dehydroxyl-11,12-didehydroandrographolide-3,19-di A pharmaceutical composition composed of succinic acid half-ester salt, Lamara or its extracts and a preparation method thereof belong to the technical field of medicine. 2. Background technology [0002] For the treatment of acute and chronic inflammation, antibiotics and hormones are currently the mainstay. Due to the increasing number of drug-resistant strains, antibiotic therapy cannot achieve satisfactory results in an increasing number of cases. Moreover, while these antibiotics kill pathogenic microorganisms, they have certain toxic and side effects on the human body, and sometimes they are even fatal. Therefore, looking for drugs with less toxic and side effects and strong antibacterial activity in Chinese herbal me...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/59A61K31/365A61P31/00A61P29/00
Inventor 蔡军
Owner 海安江理工技术转移中心有限公司
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