Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections

US20150086592A1Inactive Publication Date: 2015-03-26SEQUOIA SCI
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Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
SEQUOIA SCI
Publication Date
2015-03-26
Estimated Expiration
Not applicable · inactive patent

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Abstract

This invention describes novel adjuvant compositions and formulations with excellent stability at refrigerated and room temperatures and up to and about 37° C. that can be produced at remarkably low costs. This invention describes novel vaccine compositions and formulations to treat and prevent urinary tract infections caused by gram-negative bacteria including Escherichia coli and multi-drug resistant E. coli. This invention also describes methods of administration of said novel vaccine compositions and formulations and methods of treatment to prevent and treat urinary tract infections caused by gram-negative bacteria including E. coli and multi-drug resistant E. coli.
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Description

CROSS REFERENCE TO RELATED APPLICATIONS

[0001] This application claims benefit of U.S. Provisional Application No. 61 / 882,498 filed on Sep. 25, 2013, the contents of which are incorporated in its entirety by reference.BACKGROUND OF THE INVENTION

[0002] 1. Field of the Invention

[0003] The invention provides novel adjuvant compositions and formulations with excellent stability at refrigerated and room temperatures, and also up to about 37° C., that can be produced at remarkably low costs. These novel adjuvant compositions and formulations are used in vaccines and exhibit superior properties of enhancing immune responses to antigens while causing less severe injection site and systemic reactions. The invention also describes novel vaccine compositions and formulations to treat and prevent urinary tract infections caused by gram-negative bacteria including Escherichia coli and multi-drug resistant E. coli. The invention also provides methods of administration of said novel vaccine formulatio...

Claims

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