The invention discloses a leading-in device with a permeation sensing function. The leading-in device with the permeation sensing function comprises a time device, a containing space, a gatherer device, a display structure and a control button. The time device is in the shape of a clock and comprises a base, a clock disk surface and a closk shell ring. The containing space is arranged in the time device and a user can inject insulin agentia into the containing space. The gatherer device is arranged at the position, making contact with the skin, of the base of the time device, and the insulin agentia enters the body through skin pores in a permeating mode. The display structure is arranged at the position of the clock disk face of the time device and the timing button control value, the leading-in time setting value and the injected insulin agentia amount are all displayed through the display structure. The control button is arranged at the position of the clock shell ring and the functions of prompting of the time when injection is needed, permeation time setting and starting time switch use are achieved. Thus, the clock and the insulin agentia can be combined, and therefore the problems of injection pain, injection forgetting and field limiting are solved.