Novel disposal method for fluorine-containing acylfluoride analog compound
A treatment method and technology of amine compounds, applied in organic chemistry, preparation of carboxylic acid halides, etc., can solve the problems of workers’ health, surrounding environmental pollution, difficulty in recrystallization and purification, poor post-processing adaptability, etc., and achieve environmental protection problem, easy handling, and stable performance
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Embodiment 1
[0035] The present invention processes a fluorine-containing acyl fluoride compound (perfluorooctanoyl fluoride) by the following method:
[0036] 1. In a reactor with a stirrer, add 32 kg of methanol, and slowly add 79 kg of pyridine under stirring to mix the two evenly to obtain a mixture of methanol and pyridine;
[0037] 2. Transfer the mixture of methanol and pyridine obtained above into a closed reactor with stirrer. At room temperature of 0°C, start stirring, and slowly add 400 kg of perfluorooctanoyl fluoride to the mixture of methanol and pyridine in a dropwise manner, and continue stirring for 2 hours after the addition is complete;
[0038] 3. the reaction product obtained above is transferred to a tower still of a rectifying tower with a theoretical plate number of 60, rectifying, and obtains 395 kilograms of perfluorooctanoic acid methyl esters (about 96% yield), and reclaims 115 in the tower still The kilogram mixture, mainly the complex of pyridine and hydrogen...
Embodiment 2
[0040] The present invention processes a fluorine-containing acyl fluoride compound (trifluoroacetyl fluoride) by the following method:
[0041] 1. In a reaction kettle with a stirrer, add 32 kilograms of methyl alcohol, under stirring, slowly add 185 kilograms of tri-n-propylamine, make the two mix uniformly, obtain the mixture of methanol and tri-n-propylamine;
[0042] 2. The mixture of methanol and tri-n-propylamine obtained above is transferred to the raw material tank of a closed tube reaction system with a magnetic pump and a Venturi tube. At room temperature of 30°C, start the magnetic pump to circulate the mixture of methanol and tri-n-propylamine in the tubular reaction system, then open the valve of the acyl fluoride feed pipe, and slowly add 110 kg of trifluoroacetyl fluoride to the tubular reaction system In a mixture of methanol and tri-n-propylamine. Continue to circulate for 1 hour after adding;
[0043] 3. the reaction product obtained above is transferred t...
Embodiment 3
[0045] The present invention processes the mixture of two fluorine-containing acyl fluoride compounds (trifluoroacetyl fluoride and fluorophosgene) by the following method:
[0046] 1. In a reaction kettle with a stirrer, add 58 kg of propylene alcohol, and slowly add 31 kg of methylamine under stirring, so that the two are evenly mixed to obtain a mixture of propylene alcohol and methylamine;
[0047] 2. The mixture of propylene alcohol and methylamine obtained above is transferred to the raw material tank of a closed tower reaction system with magnetic pump and heater, and the moment saddle ring packing of PVDF is filled in the tower reactor. Start the magnetic pump to circulate the mixture of allyl alcohol and methylamine in the tower reaction system at 60°C. Then open the valve of the acyl fluoride feed pipe, and slowly add 90 kg of a 1:1 (molar ratio) mixture of trifluoroacetyl fluoride and fluorophosgene into the tower reaction system. Continue to circulate for 1 hour a...
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