Unlock instant, AI-driven research and patent intelligence for your innovation.

Nutritional composition for promoting hematopoietic stem cell proliferation and hemoglobin synthesis

A nutritional composition and hematopoietic stem cell technology, applied in the field of nutritional composition for medical and health care, can solve the problems of unsatisfactory health care effect of anemia, high recurrence rate, unavoidable side effects, etc.

Active Publication Date: 2011-12-28
珍奥集团股份有限公司
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in addition to iron deficiency, nutritional anemia is also related to the lack of folic acid, vitamins and other reasons, so the existing functional food has unsatisfactory health effects on anemia, and can only be used as supplementary food. high chance of recurrence
[0008] 2. Hematopoietic stem cell transplantation (HSCT) has two major problems of donor shortage and rejection
[0009] 3. Using gene therapy, there are still key issues to be solved to improve the transfection rate
[0010] 4. Exogenous delivery of EPO (erythropoietin) or androgen has unavoidable side effects

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Nutritional composition for promoting hematopoietic stem cell proliferation and hemoglobin synthesis
  • Nutritional composition for promoting hematopoietic stem cell proliferation and hemoglobin synthesis
  • Nutritional composition for promoting hematopoietic stem cell proliferation and hemoglobin synthesis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Nucleotides (bases or nucleosides or mononucleotides, oligonucleotides or polynucleotides, mixed nucleotides or ribonucleic acid or deoxyribonucleic acid, etc.), arginine, lysine, Cysteine, glycine, histidine, lecithin, cephalin, vitamin E, vitamin C, folic acid, vitamin B 2 , Vitamin B 6 , Vitamin B 12 , iron, zinc, manganese, wolfberry polysaccharide, grape seed extract (oligomeric anthocyanidin-GSPE, also known as proanthocyanidin) as raw materials, proportioned by weight, can be made into tablets, powders, oral liquids, Capsules etc. The amount of raw materials is calculated according to the concentration of active ingredients, etc., and the weight ratio of active ingredients should be ensured as follows: nucleotides 90-110, arginine 20-30, lysine 20-30, cysteine ​​10-20, glycine 25-35 , histidine 20-30, lecithin 110-130, cephalin 50-70, vitamin E0.4-0.6 (a-TE), vitamin C5-7, folic acid 0.02-0.04, vitamin B 2 0.05~0.07, Vitamin B 6 0.07~0.08, Vitamin B 12 0...

Embodiment 2

[0049]Others are the same as in Example 1, the amount of raw materials is calculated according to the concentration, etc., and it should be ensured that the weight ratio of the final components is as follows: nucleotide 100, arginine 25, lysine 25, cysteine ​​15, glycine 30, histamine Acid 25, lecithin 120, cephalin 60, vitamin E0.5, vitamin C6, folic acid 0.03, vitamin B 2 0.06, vitamin B 6 0.06, vitamin B 12 0.0001, iron 1, zinc 0.6, manganese 0.5, wolfberry polysaccharide 15, grape seed extract 15. The dosage for the elderly with a body weight of 60 kg is based on 1000 mg of nucleotides.

[0050] Pharmacological effects:

[0051] 1. Create basic conditions for the proliferation of bone marrow hematopoietic stem cells

[0052] (1) Nucleotide supplementation (bases or nucleosides or mononucleotides, oligonucleotides or polynucleotides, mixed nucleotides or ribonucleic acid or deoxyribonucleic acid, etc.) not only It is helpful for gene replication, self-repair of damaged...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a nutritional composition for promoting the proliferation of hematopoietic stem cells and the synthesis of hemoglobin. Acid 10-20, glycine 25-35, histidine 20-30, lecithin 110-130, cephalin 50-70, vitamin E 0.4-0.6, vitamin C 5-7, folic acid 0.02-0.04, vitamin B2 0.05- 0.07, vitamin B6 0.07~0.08, vitamin B12 0.0001~0.0002, iron 0.5~1.5, zinc 0.5~0.7, manganese 0.4~0.6, wolfberry polysaccharide 14~16, grape seed extract 14~16. Can significantly increase the number of hemoglobin (Hb), red blood cells (RBC), white blood cells (WBC) and platelets (Plt) in the blood; can stimulate the proliferation of bone marrow hematopoietic stem cells, so that the number of hematopoietic stem cells is significantly increased; significantly increase the number of mitochondria in the cells; Spleen injury has obvious recovery effect.

Description

Technical field: [0001] The invention relates to a nutritional composition for medical and health care, in particular to a nutritional composition which can obviously promote the proliferation of hematopoietic stem cells and the synthesis of hemoglobin. Background technique: [0002] According to the World Health Organization (WHO) survey, there are about 3 billion people in the world with varying degrees of anemia, of which the incidence rate is about 10% in men and more than 20% in women. In the past 10 years, the incidence of various anemias including nutritional anemia has remained high in my country, and the incidence of anemia in modern urban residents has been increasing at a rate of 10% to 15% every year. [0003] In addition to nutritional anemia, according to the etiology and pathogenesis, anemia can also be divided into two categories: anemia caused by decreased red blood cell production and excessive destruction or loss of red blood cells. [0004] Anemia due to...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/87A61P3/02A61P7/06A61K31/198A61K31/355A61K31/375A61K31/4172A61K31/4415A61K31/519A61K31/525A61K31/665A61K31/7052A61K31/714A61K31/715A61K33/26A61K33/30A61K33/32
Inventor 吴文国
Owner 珍奥集团股份有限公司