Application method of momordica grosvenori antimicrobial activity component in preventing and controlling oral disease

An application method and anti-microbial technology, applied to the application in the prevention and treatment of oral diseases, in the field of anti-microbial active ingredients, can solve problems such as unpublished application technology, and achieve the effects of broad application prospects, good market prospects and high economic benefits

Inactive Publication Date: 2008-08-20
周英
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The inventor once applied for a patent No. 200610051218.5 "Method for Extracting Biologically Active Components from Luo Han Guo Plants", but this technology only has a method for extracting antimicrobial active components, and its application technology has not yet been disclosed

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Embodiment 1 prepares buccal tablets containing Luo Han Guo antimicrobial active ingredients, the main drug amount is: 0.3g / tablet

[0019] Monk Fruit Antimicrobial Active Ingredients Extract 30g

[0020] Mogroside 1g

[0021] Mannitol 44g

[0022] Dextrin 20g

[0023] Menthol 0.5g

[0024] HPMC 4.0g

[0025] Magnesium stearate 0.5g

[0026] Anhydrous ethanol amount

[0027] Preparation method: fully mix the antimicrobial active ingredient extract of Momordica grosvenori, mogroside, mannitol, and dextrin in the prescribed amount, and sieve, dissolve menthol in an appropriate amount of ethanol, and add it to the mixed powder; use 2% HPMC solution as the Adhesives made of suitable soft materials, granulated with a 16-mesh sieve, granulated with a 14-mesh sieve after drying, added with magnesium stearate, mixed evenly, and pressed into tablets to obtain 100 tablets.

[0028] Product Efficacy: This lozenge is antibacterial and anti-inflammatory, cools blood and relie...

Embodiment 2

[0029] Embodiment 2 prepares the buccal tablet containing the antimicrobial active ingredient of Luo Han Guo, and the drug content is: 0.25g / tablet

[0030] Luo Han Guo Extract 25g

[0031] Mannitol 50g

[0032] Dextrin 20g

[0033] Menthol 0.5g

[0034] HPMC 4.0g

[0035] Magnesium stearate 0.5g

[0036] Anhydrous ethanol amount

[0037] The preparation method: fully mix and sieve the prescription quantity of Luo Han Guo extract, mannitol and dextrin, dissolve the prescription quantity of menthol in an appropriate amount of ethanol, and add it to the mixed powder. Use 2% HPMC solution as a binder to make a suitable soft material, granulate with a 16-mesh sieve, sieve the granules with a 14-mesh sieve after drying, add magnesium stearate, mix well, and press into tablets to obtain 100 tablets.

[0038] Product Efficacy: This lozenge is antibacterial and anti-inflammatory, cools blood and relieves pain. It can be used to treat oral and throat diseases such as dental cari...

Embodiment 3

[0039] Embodiment 3 prepares buccal tablets containing Luo Han Guo antimicrobial active ingredients, the main drug amount is: 0.15g / tablet

[0040] Monk Fruit Antimicrobial Active Ingredients Extract 15g

[0041] Mogroside 4.5g

[0042] Nuciferol Extract 5g

[0043] Tea Extract / EGCG 0.5g

[0044] Mannitol 50g

[0045]Dextrin 20g

[0046] Menthol 0.5g

[0047] HPMC 4.0g

[0048] Magnesium stearate 0.5g

[0049] Anhydrous ethanol amount

[0050] The preparation method: fully mix the antimicrobial active ingredient extract of Luo Han Guo, mogroside, mannitol, and dextrin in the prescribed amount, and sieve, dissolve the menthol in an appropriate amount of ethanol, and add it to the mixed powder. Use 2% HPMC solution as a binder to make a suitable soft material, granulate with a 16-mesh sieve, sieve the granules with a 14-mesh sieve after drying, add magnesium stearate, mix well, and press into tablets to obtain 100 tablets.

[0051] Product Efficacy: This lozenge is anti...

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PUM

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Abstract

The invention discloses an oral disease control application method of fructus momordicae antimicrobial active ingredients, in particular to a method for making the fructus momordicae with antimicrobial active extracts prepare into drugs, food and commodities with function of oral health care and therapy, and for making the fructus momordicae with antimicrobial active extracts content in the above products reach 0.1 to 25 percent. The drugs with function of oral therapy of the invention can adopt various preparations, such as tablets, spray, powder, film agent, paint agent, ointment, gel agent and gargle agent; food and commodities with function of oral health care comprises chewing gum, beverage, tea, wine, toothpaste and dentifrice. The invention applies the extracted strong antimicrobial active ingredients from the leaves, vines, roots, stems and fruits of the ructus momordicae on human oral disease for the first time; develops drugs for controlling dental caries, periodontitis, gingivitis, toothache and hemorrhage, oral ulcer, halitosis, pharyngitis, throat pain and other diseases, food and commodities with function of oral health care. Thereby, the application method has the advantages of wide application prospect, important social benefits and economic benefits.

Description

technical field [0001] The invention relates to the application of biological active ingredients of natural materials, in particular to the application method of antimicrobial active ingredients extracted from Luo Han Guo plants in preventing and treating oral diseases. Background technique [0002] The plant of Luo Han Guo is a perennial root climbing vine of Cucurbitaceae (Siraitiagrosvenori Swingle), and its fruit is known as the "Oriental God Fruit". Traditional Chinese medicine believes that Luo Han Guo is sweet, sour, and cool in nature. It has the effects of clearing heat and cooling blood, promoting body fluid and relieving cough, smoothing intestines and detoxifying, rejuvenating skin and skin, moistening lungs and reducing phlegm, etc. Cough, sore throat, constipation, thirst and irritability. The fruit of Luo Han Guo has been used in traditional Chinese medicine for centuries to prevent and treat sore throats, but little research has been done on the non-fruit pa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/42A61K9/00A61K9/06A61K9/12A61K9/14A61K9/20A61K8/97A61Q11/00A61P1/02A61P11/04A23L1/30A61K125/00A61K127/00A61K131/00A61K135/00
Inventor 周英黄赤夫王慧娟
Owner 周英
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