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Ketogenic mix preparation suitable for treating intractable epilepsy

A technology for refractory epilepsy and ketone production, which is applied in medical preparations containing active ingredients, drug combinations, organic active ingredients, etc.

Inactive Publication Date: 2008-09-24
邓荣光
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Since the specific implementation process of the ketogenic diet has to maintain the ratio of the mixture of fat, carbohydrates and protein in the diet for a long time, it is difficult for patients to prepare by themselves, especially for infant patients and adult patients with mental retardation without special care. More difficult to implement, that is, it is difficult to adopt the eating method of ordinary food
It is precisely because the nutritional content of various foods is difficult to estimate, and the influence of unknown factors in ordinary eating often leads to treatment failure.

Method used

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Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0019] The characteristics of this embodiment are: the basic formula is composed of fat, protein and carbohydrates, and sufficient amounts of essential vitamins, minerals and amino acids for promoting the growth and development of the human body and brain and promoting fat metabolism are added to the basic formula; The material state of the part is powder, ointment, liquid or solid.

[0020] The basic formula components and their mass percentages in the ketogenic mixed preparation are shown in Table 1.

[0021] Table 1:

[0022] nutritional information

content per 100g

Energy (Kcal)

800kcal

protein (g)

15

Carbohydrates (g)

5

Fat (g)

80

fat: protein + carbohydrates

4∶1

[0023] A small amount of essential vitamins, minerals and amino acids that promote the growth and development of the human body and brain and promote fat metabolism are shown in Table 2 in the ketogenic mixed preparation...

specific Embodiment 2

[0037] The feature of this embodiment is: the added amino acids that promote the growth and development of human body and brain and promote fat metabolism include L-lysine, L-carnitine and taurine.

specific Embodiment approach

[0039] In the basic formula, the mass percentages of each component are as follows: the fat is adjusted in the range of 65-80%, the protein is adjusted in the range of 15-25%, and the carbohydrate is adjusted in the range of 5-15%; The premise is to ensure that fat: protein + carbohydrate = 4:1 or 3:1.

[0040] The added vitamins include: 380μg±50μg of vitamin A, 4ug±0.5μg of vitamin D, 5mg±0.5mg of vitamin E, 45mg±5mg of vitamin C, 30±2ug of vitamin K, and 0.6 mg±0.05mg, riboflavin 0.6mg±0.05mg, vitamin B6 0.6mg±0.05mg, vitamin B12 0.8ug±0.05ug, vitamin H 10ug±1.5ug, vitamin B complex 150mg±15mg, inositol ( Fiber sugar, inositol) 30mg ± 5mg.

[0041] The added minerals include: 500mg±50mg of sodium, 700mg±70mg of potassium, 700mg±70mg of chlorine, 500mg±50mg of calcium, 400mg±40mg of phosphorus, 110mg±11mg of magnesium, 8mg±0.8 mg, copper 0.6mg±0.06mg, zinc 8mg±0.8mg, manganese 0.65mg±0.06mg, iodine 70ug±7ug, molybdenum 15ug±1.5ug, selenium 20ug±2ug, chromium 15ug±1.5ug;

...

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PUM

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Abstract

The invention relate to a ketogenesis mixture preparation applicable for treating refractory epilepsy, which is characterized in that: (1) fat, protein and carbohydrate form the basic prescription, a small amount of essential vitamins, minerals and aminophenol promoting the growth and the development of the human body and brain and promoting the metabolism are added in the basic prescription; (2) in the basic preparation, the weight percentages of the components are respectively that: fat 70-80 percent, protein 15-20 percent, carbohydrate 5-10 percent; (3) the physical states of all the components in the basic preparation are powder, ointment, aqua, or solid state agent. The physical states of the ketogenesis mixture preparation are powder granule, electuary, liquid agent, tablet, capsule or other solid state agent. The ketogenesis mixture preparation aims at the special nutrition requirement of Chinese, nutritional ingredient promoting the development of the brain and the metabolism is added in, the curative efficiency on refractory epilepsy reaches 80 percent, which reaches or exceeds the curative effect of the equivalent product abroad.

Description

technical field [0001] The invention relates to a ketogenic mixed preparation suitable for treating refractory epilepsy, especially a ketogenic mixed preparation suitable for Chinese people to treat refractory epilepsy. It belongs to the field of special food technology. Background technique [0002] Currently, there are 6 million epilepsy patients in my country, 25% of whom are refractory epilepsy. At present, it is generally believed in the world that new antiepileptic drugs are only effective for 30-40% of children with refractory epilepsy (more than 50% reduction in seizures); while the ketogenic diet is effective for 50-80% of children with refractory epilepsy, 30% 90% of seizures can be reduced in 90% of children, and seizures can be completely controlled in 10-20% of patients. Apparently the ketogenic diet is more effective than the newer antiepileptic drugs. [0003] The ketogenic diet (ketogenic diet) is a special diet therapy with high fat, low carbohydrate and ...

Claims

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Application Information

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IPC IPC(8): A61K38/00A61P25/08A61K31/047A61K31/07A61K31/122A61K31/185A61K31/197A61K31/198A61K31/205A61K31/355A61K31/375A61K31/4188A61K31/4415A61K31/455A61K31/51A61K31/519A61K31/525A61K31/714A61K31/715
Inventor 邓荣光
Owner 邓荣光
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