Polypeptides of anti-measles virus and human immunodeficiency virus and use

A technology of immunodeficiency virus and measles virus, which is applied in the field of anti-measles virus and human immunodeficiency virus anti-virus polypeptide of East Asian scorpion, and the field of polypeptide with high-efficiency anti-virus function, which can solve the instability and preventive effect of its own genetic material Reduce the problem of easy mutation and other problems, and achieve the effect of good water solubility, good inhibitory effect and no side effects
CN101284870BInactive Publication Date: 2011-09-14WUHAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
WUHAN UNIV
Publication Date
2011-09-14
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses scorpion toxin antiviral polypeptide and a use of the same. Scorpion toxin antivirotic polypeptide (AVP-W1) is obtained through a molecular biological and chemical synthesis method, and then the antiviral activity of the AVP-W1 on measles virus (MeV) and human immunodeficiency virus (HIV) is measured through adopting an antibody neutralization method; moreover, the measurement shows that the AVP-W1 can effectively inhibit virus infection at a low concentration. The AVP-W1 has a tremendous prospect in making applied medicine which can cure or prevent a disease caused byvirus. Moreover, the antiviral peptide of the invention has high activity on MeV and HIV and a simple method, and can be developed as antiviral medicine.
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Description

technical field

[0001] The invention belongs to the field of biotechnology, and more specifically relates to a polypeptide with high-efficiency antiviral function. Specifically, the present invention relates to the use of an antiviral polypeptide of the scorpion scorpion in anti-measles virus (MeV) and human immunodeficiency virus (HIV). Background technique

[0002] Virus infection is a disease that seriously endangers human health, and this problem has plagued human beings for many years. As early as 412 BC in ancient Greece, Hippocrates had already described influenza-like diseases; from 1742 to 1743, influenza caused by influenza viruses had affected 90% of Eastern Europeans; from 1889 to 1894 The "Russian flu" that swept through Western Europe in 1950 had a wide range of morbidity and a high mortality rate; in 1918, a deadly flu swept the world, causing 20 to 50 million deaths; the "Asian flu" in 1957 and the "Hong Kong flu" in 1968 According to statistics in the Unit...

Claims

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