Novel allantoin synthesis process

Abstract

The invention discloses a novel technique for synthesizing allantoin, comprising the following steps that: alkali is added into a solvent of methanol or ethanol or water in a stirring state, methyl dichloroacetate or dichloroacetic acid are dropped to react, inorganic acid is added into the mixed solution to react, and a dihydroxy acetate solution is obtained after filtration, the obtained dihydroxy acetate solution is distilled, carbamide and the inorganic acid are added into the mixture, the mixture is stirred at a temperature of between 70 and 90 DEG C and reacts on the condition of heat preservation, and the reaction product is cooled to the room temperature, washed to be neutral and dried so that the product of the allantoin is obtained. The method takes the methyl dichloroacetate or the dichloroacetic acid as a raw material to synthesize the allantoin, lowers the production cost, has quality improvement and has a yield up to about 62 percent; meanwhile, a chloroacetic acid mother liquid is utilized indirectly to reduce the environment pollution caused by emission. The method does not pollute the environment, has simple and convenient operation and low energy consumption, and meets the requirements on energy conservation and emission reduction.

Description

technical field [0001] The invention relates to a synthetic process of a chemical product, in particular to a new synthetic process of an allantoin product. Background technique [0002] Allantoin (allantoin), also known as 5-ureidohydantoin, is an important urea deep-processing product, which belongs to imidazole heterocyclic compounds, and its chemical name is: 1-ureidodiazapentane-2, 4-diketone or 2,5-dioxo-4-imidazolidinyl urea, formula C 4 h 6 N 4 o 3 , molecular weight 158.12. Allantoin is an important fine chemical product. This product has physiological functions such as promoting cell growth, accelerating wound healing, and softening cuticle proteins. It is widely used in the production of medicine, cosmetics, agriculture and industrial preservatives. [0003] At present, the method for preparing allantoin is mainly to synthesize glyoxylic acid and urea, or to obtain glyoxylic acid by catalytic oxidation of glyoxal and then synthesize two methods with urea, but...

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Problems solved by technology

[0003] At present, the method for preparing allantoin is mainly to synthesize glyoxylic acid and urea, or to obtain glyoxylic acid by catalytic oxidation of glyoxal and then synthesize two methods with urea, but the production of allantoin by the above method has low yield and low cost. High, recrystallization is required to obtain the finished product of allantoin after the crude product of allantoin is produced, the process is complex, and the yield of allantoin is only about 56%, and the content of active matter is only about 98%, and the amount of acid used Therefore, the pollution of the acid solution is large, the production equipment is seriously corroded, and because glyoxylic acid contains impurities such as oxalic acid, glyoxal, and nitric acid, the refining process is complicated, resulting in waste of energy and damage to the environment, failing to achieve energy saving and reduction. platoon requirements