Method for preparing farina microcapsule medicament

Abstract

The invention relates to a method for preparing a medicament by using a natural rape pollen microcapsule as a carrier. The method comprises the following steps: drying the natural rape pollen, using drugs or active components as substances embedded in a pollen sac, and diffusing the substances to the interior of the pollen sac through germ pores of the pollen sac, wherein the medicaments or the active components are remained in the interior of the pollen sac after physical or chemical reactions, and are dried at lower temperature after centrifugation to be prepared into a pollen microcapsule drug. The method solves the defects that the prior method needs complicated microencapsulation equipment and has complicated process and low success rate, is lack of a simple encapsulating method applicable to all capsule cores, is not continuous in an operation method, is not advantageous to joint production, and generates wastes during packaging capsule. The method has the advantages: firstly, aready-made pollen sac is used, the external form of the pollen sac is stable, and the microcapsule is does not need to be made over again, thus the steps and process for preparing the microcapsule are saved; secondly, the pollen microcapsule is not affected by the filled substances and the solvent thereof,, and the ranges of drug loading and active components are wide; and thirdly, the microcapsule drug has stable property, and basically generates no waste.

Description

technical field [0001] The invention relates to a solvent embedding technique, in particular to a medicine preparation method using natural rape pollen microcapsules as a carrier. Background technique [0002] Microcapsules are microcapsules with a particle size of 5-500 μm formed by embedding solid or liquid drugs with natural or synthetic polymer materials. Microcapsules can be prepared into powders, granules, capsules, tablets, injections and other dosage forms, so that they can delay drug release, improve drug stability, mask bad odor, reduce gastrointestinal side effects, and reduce compound drugs. Incompatibility, improve the physical properties of some drugs (such as compressibility, fluidity), can make liquid drugs into solid preparations, and play a targeting role. [0003] The process of preparing microcapsules is called microencapsulation technology, referred to as microencapsulation, the wrapped drug is called capsule core, and the polymer material used to wrap ...

AI Technical Summary

Problems solved by technology

[0006] Before the present invention, in the actual microencapsulation process, there were complex microencapsulation processing equipment, and the process was complicated and the success rate was not high. The operation proficiency has a great influence, and there is a lack of a simple encapsulation method suitable for all capsule cores. The operation method is discontinuous, which is not conducive to the linkage production, and the encapsulation is easy to produce waste products and other defects.

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