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Procyanidin capsules and process for manufacturing same

A proanthocyanidin and capsule technology, applied in the directions of capsule delivery, organic active ingredients, skin diseases, etc., can solve the problem of no patent reports, and achieve the effects of preventing cross-linking, protecting cardiovascular health, and maintaining skin elasticity

Inactive Publication Date: 2010-02-10
LANZHOU INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many products developed using proanthocyanidins, but there is no patent report on the functional food developed by using astragalus polysaccharides for health care and stabilizing proanthocyanidins.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Get 200 grams of proanthocyanidins, 200 grams of astragalus polysaccharides, and 70 grams of gelatin dissolved in 460 grams of water, set the spray drying air inlet temperature to 180 ° C, and the feed rate to 30 ml / min, and spray dry to make proanthocyanidin microcapsule particles. 184 grams of casein phosphopeptides, 6 grams of magnesium stearate and microcapsule granules were mixed in a multidimensional mixer for 30 minutes. After fully mixed, add distilled water as a wetting agent to make a soft material. The prepared soft material is put into a swinging granulator for granulation with a 16-mesh screen, and then the wet granules are dried in a hot air circulation drying oven at a temperature below 60°C. Dried granules are granulated with 18 meshes of a granulator to obtain uniform granules, and the capsule specification is 2# in capsules, and 8000 proanthocyanidin capsules are made altogether, and the proanthocyanidin content of the capsules is 24 mg / grain.

Embodiment 2

[0026] Get 200 grams of proanthocyanidins, 200 grams of astragalus polysaccharides, and 70 grams of gelatin dissolved in 900 grams of water, set the spray drying air inlet temperature to 190 ° C, and the feed rate to 40 ml / min, and spray dry to make proanthocyanidin microcapsule particles. 184 grams of D-mannitol, 6 grams of magnesium stearate and microcapsule granules were put into a multidimensional mixer and mixed for 30 minutes. After fully mixed, add distilled water as a wetting agent to make a soft material. The prepared soft material is put into a swinging granulator for granulation with a 16-mesh screen, and then the wet granules are dried in a hot air circulation drying oven at a temperature below 60°C. Dried granules are granulated with 18 meshes of a granulator to obtain uniform granules, and the capsule specification is 2# in capsules, and 8000 proanthocyanidin capsules are made altogether, and the proanthocyanidin content of the capsules is 24 mg / grain.

Embodiment 3

[0028] Get 250 grams of proanthocyanidins, 340 grams of astragalus polysaccharides, 70 grams of gelatin dissolved in 1980 grams of water, set the spray drying air inlet temperature to 200 ° C, and the feed rate to 50 ml / min, and spray dry to make proanthocyanidin microcapsule particles. 6 grams of magnesium stearate and microcapsule granules were put into a multidimensional mixer and mixed for 30 minutes. After fully mixed, add distilled water as a wetting agent to make a soft material. The prepared soft material is put into a swinging granulator for granulation with a 16-mesh screen, and then the wet granules are dried in a hot air circulation drying oven at a temperature below 60°C. Dried granules are granulated with 18 meshes of a granulator to obtain uniform granules, and the capsule specification is 2# in capsules, and 8000 proanthocyanidin capsules are made altogether, and the proanthocyanidin content of the capsules is 24 mg / grain.

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PUM

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Abstract

The invention discloses a procyanidin capsules and a process for manufacturing the same. The capsules are manufactured by taking procyanidin and astragalus polysaccharide as main materials and caseinphospho peptides or D-mannitol, magnesium stearate and gelatin as auxiliary materials. The capsule has the advantages of being conveniently taken, avoiding absorbing moisture and having functions of immunoregulation, anti-ageing and radiation hardening, protecting cardiovascular health by removing free radicals in vivo, and preventing crosslinking of skin collagens, inhibiting pigmentation, dispelling wrinkles and whitening the skin, keeping skin elasticity and delaying ageing.

Description

technical field [0001] The invention relates to a proanthocyanidin capsule and a production process thereof, more specifically, the present invention relates to a proanthocyanidin capsule with proanthocyanidin and astragalus polysaccharide as main raw materials and a production process thereof. Background technique [0002] In recent years, it has been found that oral administration of proanthocyanidins can effectively reduce the pigmentation of female patients with chloasma, and at the same time inhibit the activity of tyrosinase that forms freckle melanin, resist the pigmentation caused by ultraviolet rays, thereby reducing the occurrence of freckles and achieving skin hypertrophy. Whitening effect; proanthocyanidins can quickly remove free radicals, prevent excessive cross-linking of collagen, restore smooth and delicate skin, and prevent skin aging. Therefore, proanthocyanidins are known as "skin vitamins" and "oral cosmetics" in Europe and America. At present, there ar...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61K31/352A61K31/715A61P17/18A61P17/16A61P17/00
Inventor 郭勇廖原徐健邵士俊
Owner LANZHOU INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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