187results about How to "Avoid crosslinking" patented technology

A tubing includes a layer of cross-linked polyamide. The polyamide layer can include a cross-linking aid, such as triallyliscocyanurant or TAIC, to assist in cross-linking the layer. When the polyamide layer is exposed to high-level radiation, the polyamide layer cross-links to provide a layer having high temperature resistance and high glycol resistance. In another embodiment, the tubing includes a first layer of a cross-linked thermoplastic and a second layer to form a multi-layer tubing. The thermoplastic of the first layer can be polyamide, aromatic nylon, polyolefins, polyvinyl chloride or polyester.

The invention relates to a solvent-free method for preparing a polyether modified polysiloxane antifoaming agent. The solvent-free method is characterized by comprising the following steps: 1, adding siloxane-oxyalkylene copolymer which is spirally evaporated to remove water to a reaction kettle, then filling nitrogen, and adding an antioxidant BHT (Butylated Hydroxytoluene); 2, adding a platinum catalyst to the reaction kettle, and heating the reaction kettle and stirring, wherein the provided temperature for heating is at 50 to 60 DEG C; 3, adding low-hydro silicone oil and a 4A molecular sieve to the reaction kettle for starting hydrosilylation reaction, and controlling the temperature in the reaction kettle to reach 70 to 110 DEG C, then stirring at constant temperature for 1 to 2 hours; 4, adding hydrochloric acid or sulfuric acid to the reaction system, then stirring to neutralize, and reacting for 1 to 1.5 hours at 85 to 95 DEG C; and 5, spirally evaporating to obtain the reacting product which is the polyether modified polysiloxane after the reaction. The solvent-free method is high in chemical conversion rate; and the prepared polyether modified polysiloxane antifoaming agent is transparent and high in purity, so that the antifoaming performance of the polyether modified polysiloxane antifoaming agent is high.

Methods of making a wear and oxidation resistant medical implant are disclosed.

The invention provides a method for synthesizing a solid polycarboxylic water reducing agent, comprising the following steps: using a monomer containing the nonsaturated group to react with an organic solvent, after the reaction, adding an alkaline substance for neutralization, and carrying out centrifugation to obtain a polycarboxylic acid water reducer, then drying the prepared polycarboxylic acid water reducer to obtain the solid polycarboxylic acid water reducing agent. By using a low temperature method to prepare the solid polycarboxylic acid water reducing agent , the crosslinking of the polycarboxylic acid water reducer due to high temperature spray drying is avoided, and the structure of the polycarboxylic acid water reducer is destroyed, thus the solid polycarboxylic acid water reducing agent with excellent performance is obtained.

The invention relates to the field of high molecular sealing materials and discloses a single-component silane modified polyether sealant composition and a sealant prepared from the single-component silane modified polyether sealant composition. The single-component silane modified polyether sealant composition disclosed by the invention is prepared from silane modified polyether resin, alkoxy terminated polydimethylsiloxane, a plasticizing agent, reinforcing filler, a water removal agent, a light stabilizing agent, an ultraviolet absorbent, a coupling agent and a catalyst. The sealant disclosed by the invention has the advantages of good smell, good ageing resistance, high recovery rate and the like.

The invention relates to a method for producing linear hydroxyl-terminated polydimethylsiloxane, wherein the method comprises the following steps of: washing dimethyldichlorosilane hydrolysate serving as an initiative material to remove remained chloride ions; polymerizing the hydrolyzate in the presence of a basic size catalyst; after the polymerization reaches a certain degree, heating directly to decompose catalyze; ending the reaction; and removing low-boiling matters at the same time to obtain products. The linear hydroxyl-terminated polydimethylsiloxane produced by the invention has the characteristics of uniformly distributed molecular weight, controllable viscosity, good repeatability and the like.

The present invention concerns compositions and methods of use of a humanized Class III anti-CEA antibody, comprising the heavy and light amino acid sequences SEQ ID NO:1 and SEQ ID NO:2. The antibody is effective to treat CEACAM5-expressing tumors, either alone or in combination with one or more therapeutic agents. Drug conjugated Class III anti-CEA antibodies, such as SN-38 or P2PDox immunoconjugates, are particularly efficacious. Surprisingly, the antibody-drug conjugates (ADCs) exhibit high anti-cancer efficacy, while exhibiting low levels of systemic toxicity that are readily treated with standard amelioration techniques. Antibodies and/or immunoconjugates comprising the amino acid sequences SEQ ID NO:1 and SEQ ID NO:2 are surprisingly efficacious for therapy of solid tumors, even when the tumor has proven resistant to standard anti-cancer therapies.

A method for synthesis of linking polysaccharide chiral stationary phase, includes the following steps: 1) in the reactor with organic solvent, polysaccharide and derivative solvent of polysaccharide react with including functional group which can react with polysaccharide hydrocarbon radical, then though centrifugal separation the solid substance is collected; 2) coat the prepared polysaccharide derivative containing trihydroxyme or on the surface of silica gel matrixof chromatogram filler, then they are mixed with toluene and pyridine in reactor , cooled after reaction, then use tetrahydrofuran and carbinol separately to wash the creature, which are dried in vacuum, acquiring the linking polysaccharide chiral stationary phase. Its advantages are: wide field of use, simple and rapid preparation.

The invention discloses a hexapeptide stock solution and a preparation method thereof. A hexapeptide stock solution, the composition includes the following main components: maltooligosaccharide glucoside/hydrogenated starch hydrolyzate 0.2-0.7%, butanediol/water/peony root extract 0.1-0.5%, acetyl hexapeptide ‑80.5~1.6%, yeast extract 0.4~1.6%, salicylic acid/dextrin/xanthan gum/pullulan 0.2~0.7%, carnosine 0.1~0.21%. The hexapeptide stock solution prepared by the invention has good anti-aging and moisturizing effects.

The invention discloses a non-woven fabric surface heavy nitrogen coupling gelatin adsorbing material and a preparation method thereof. The method comprises the following steps of: grafting an unsaturated monomer with carboxy to the surface of a macromolecule non-woven fabric base material by using an ultraviolet induction technique so as to introduce the carboxy; furthermore introducing aromatic amine through catalytic condensation of aroma diamine and carboxy; subsequently, converting the aromatic amine into diazo salt; coupling and immobilizing the gelatin on the surface of the non-woven fabric through diazo coupling reaction; and finally, soaking in hot water and eliminating the uncoupled gelatin so as to prepare the non-woven fabric surface diazo coupling gelatin absorbing material. The absorbing material is good in hydrophilicity, namely, the water absorption rate is greater than 292.3%; the solid load and the absorption rate of the gelatin can be adjusted in a large range, the absorbing material has high absorption capability for tannin; and when the tannin concentration is 200-400mg/L, the balance absorption capacity is within 16.8-53.2mg/g, and the absorption balance can be achieved within 3 hours.

A preparation method of nascent fiber for production of carbon fiber comprises the following steps: uniformly mixing modified lignin or commercialized lignosulfonate and a solvent to prepare a solution a; uniformly mixing polyacrylonitrile resin and the solution to prepare a solution b, or directly using a de-monomerized polyacrylonitrile spinning solution as the solution b; blending the solution a and the solution b; keeping the blended solution at the constant temperature of 40-80 DEG C to obtain a uniform spinning solution with solid content being 12-33 wt%; pressing the spinning solution into coagulating bath through a spinneret plate to generate polyacrylonitrile/modified lignin nascent fiber; and finally winding at constant rate to obtain the nascent fiber for production of carbon fiber. The preparation method of the invention has advantages of low cost and high quality.

The invention relates to a polyethylene-polystyrene resin and a preparation method thereof. The preparation method comprises the following steps of: performing pre-irradiation treatment on polyethylene resin by using beta rays or gamma rays; adding the polyethylene resin after the pre-irradiation treatment, a dispersing agent, a functional monomer, an emulsifying agent, a nucleating agent and a homopolymerization inhibiting agent into a reactor to perform suspension graft polymerization reaction for a certain period of time at a certain temperature; and filtering, washing and drying a suspension graft product to obtain the polyethylene-polystyrene resin. The concentrations of macromolecular peroxides generated by the pre-irradiation are distributed evenly, so side reactions such as monomer homopolymerization, polymer crosslinking and/or degradation and the like caused by a micromolecule chemical initiator are avoided; the percent grafting ratio reaches 21 to 42 percent; the homopolymerization inhibiting agent reduces the homopolymerization of the monomer in the suspension grafting process; and the polyethylene-polystyrene resin has the tensile strength of more than 22 MPa, breaking elongation of over 90 percent and elastic modulus of more than 480 MPa, and has good mechanical properties such as strength, tenacity, impact strength and the like.

A composite of a resin member bonded to a rubber member is obtained by molding a resin molding element and a rubber molding element with contacting said elements each other, and vulcanizing or crosslinking the rubber molding element, wherein said resin molding element is either of a resin composition and a resin member, each comprising the thermoplastic resin; and said rubber molding element is either of a rubber composition and a rubber premolded article, each comprising at least an unvulcanized silicone rubber, and a radical-generating agent (e.g., organic peroxides) being activating on a surface to be contacted with said resin molding element. The thermoplastic resin includes a polyamide-series resin, a polyester-serires resin, a PPE-series resin, etc. The unvulcanized rubber composition may comprise a polyfunctional compound having plural polymerizable groups. Such a process can give a composite composed of a thermoplastic resin molded article bonded to a vulcanized silicone rubber molded article directly and firmly without an adhesive treatment.

A semi-conductive roll is provided including a shaft, a low-hardness base layer formed on an outer circumferential surface of the shaft, and a coating layer formed by coating the low-hardness base layer radially outwardly. The coating layer includes one of a rubber material and an elastomer material that is crosslinked by at least one resin crosslinking agent.

The invention provides a flame retardation cladding adhesive for polystyrene prefoamed beads, and a product thereof, and concretely relates to a flame retardation cladding adhesive specially used for cladding polystyrene prefoamed beads, and a modified polystyrene flame retardation foam sheet made by using the flame retardation cladding adhesive. The polystyrene prefoamed bead flame retardation cladding adhesive adopting modified urea formaldehyde resin with toughening and film forming performances as an adhesion medium has excellent flame retardation characteristic, and can effectively improve the flame retardation performance of a polystyrene foam material; and the modified urea formaldehyde resin with toughening and film forming performances adopted in the invention allows a weak acidic substance to be used as a curing agent of the flame retardation cladding adhesive, so damages of a strong acid curing agent similar to phenolic resin to human bodies, environment and apparatuses are avoided.

A quick settling-type fluccolant is prepared from polyacrylamide, silicate, quartz sand, urea and carbonate through kneading, granulating, drying and pulverizing.

The invention relates to a polyethylene-polystyrene foam, which is formed in a way that polystyrene is grafted on a molecular chain of polyethylene to connect the polyethylene with the polystyrene by a covalent chemical bond, wherein the grafting ratio mass percent of the grafted polystyrene is 25-60%, and the volume density of the polyethylene-polystyrene foam is 27-208kg/m<3>. The preparation method comprises the following steps: carrying out pre-irradiation treatment on the polyethylene; and adding the polyethylene after the pre-irradiation treatment, dispersant, functional monomer, emulsifying agent, nucleating agent and homopolymerization depressor to a reaction vessel to be subject to suspension graft polymerization reaction, adding foaming agent, cooling the reaction product, filtering, washing with water, drying, and heating to obtain the polyethylene-polystyrene foam. The polyethylene-polystyrene foam has the advantages of excellent mechanical property, favorable rebound elasticity, good stress cracking resistance, high impact absorbing capacity and the like, combines the flexibility of polyethylene foam and the rigidity of polystyrene foam, and is used in the fields of vehicles, buildings, packaging, heat preservation, heat insulation and the like.

The invention discloses a procyanidin capsules and a process for manufacturing the same. The capsules are manufactured by taking procyanidin and astragalus polysaccharide as main materials and caseinphospho peptides or D-mannitol, magnesium stearate and gelatin as auxiliary materials. The capsule has the advantages of being conveniently taken, avoiding absorbing moisture and having functions of immunoregulation, anti-ageing and radiation hardening, protecting cardiovascular health by removing free radicals in vivo, and preventing crosslinking of skin collagens, inhibiting pigmentation, dispelling wrinkles and whitening the skin, keeping skin elasticity and delaying ageing.

The invention belongs to the technical field of cleaning of polymer flooding produced liquid treatment equipment in the petroleum industry and provides a descaling cleaning agent for poly-containing dirt on polymer flooding produced liquid treatment equipment. The descaling cleaning agent comprises the following components in percentage by weight: 8-20wt% of polymer dispersant, 20-40wt% of oil scavenger, 35-55wt% of mutual solvent, 1-6wt% of metal ion chelating agent and the balance of water. The descaling cleaning agent provided by the invention has a good removal effect on the poly-containing dirt on electric dehydration systems, heat exchangers and sewage treatment systems and has stable performance, thereby being suitable for ocean transportation and long-term storage.

The invention relates to the discovery that 3-deoxyglucosone (3DG) and other alpha-dicarbonyl sugars associated diseases and disorders are present and produced in the skin. Further, the invention relates to the discovery that amadorase, an enzyme that mediates 3DG synthesis, is also present in the skin. Thus, the invention further relates to methods of inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin thereby treating or prevention various diseases, disorders or conditions. Additionally, the invention relates to treatment of various diseases, disorders or conditions associated with or mediated by oxidative stress since 3DG induces ROS and AGEs, which are associated with the inflammatory response caused by oxidative stress.

The present invention concerns improved methods and compositions for neoadjuvant use of antibody-drug conjugates (ADCs) in cancer therapy, preferably ADCs comprising an anthracycline or camptothecin, more preferably SN-38 or pro-2-pyrrolinodoxorubicin (P2PDox). The ADC is administered as a neoadjuvant, prior to treatment with a standard anti-cancer therapy such as surgery, radiation therapy, chemotherapy, or immunotherapy. Neoadjuvant use of the ADC substantially improves the efficacy of standard anti-cancer therapy and may debulk a primary tumor or eliminate micrometasteses. In most preferred embodiments, neoadjuvant ADC in combination with a standard anti-cancer therapy is successful in treating cancers that are resistant to standard treatments, such as triple-negative breast cancer (TNBC).

The invention relates to an LED coating for encapsulating quantum dots by multiple layers. The LED coating comprises a traditional encapsulation material layer and a plurality of encapsulation particles of quantum dots and scattered particles, which are scattered in the traditional encapsulation material layer, wherein from inside to outside, the encapsulation particle of the quantum dot and the scattered particle comprises a quantum dot, a compatible polymer layer and a water and oxygen barrier film layer in sequence, and a plurality of inorganic nano scattered particles are scattered in thecompatible polymer layer. The compatible polymer and the quantum dot are highly compatible, so that the high surface energy property of the quantum dot is prevented from damaging colloid crosslinking,and the quantum dot is more stable. According to the LED coating, the quantum dot is wrapped in the compatible polymer and then is crushed into particles, the surface of the particle is encapsulatedby the water and oxygen barrier film layer, and finally, the obtained particles are scattered in another colloid, so as to prepare the quantum dot coating, therefore, the quantum dots are less likelyto gather so as to maintain the luminescence performance; and the multilayer encapsulation structure improves the water and oxygen blocking performance of the quantum dot coating.