The invention relates to a total dose radiation hardening I-shaped gate layout structure, which comprises an active region, a field oxidation region outside the active region, and an I-shaped gate overlapped with the active region. The part on the active region, which is not overlapped with the I-shaped gate, is divided into a rectangle source region and a rectangle drain region. The total dose radiation hardening I-shaped gate layout structure arranges a gate oxidation layer below the I-shaped gate layer of the whole region where the I-shaped gate and the active region are overlapped, not only comprises an a region between the source region and the drain region, but also comprises b regions on the upper and lower parts of the source region and the drain region. The formation of the b regions pushes off the distances among the source region, the drain region and the field oxidation region, thus, the total dose radiation hardening I-shaped gate layout structure avoids a field region, cuts off the accesses between an edge radiation parasitic channel of the field oxidation region and the source region and the drain region, better solves the parasitic leakage problem caused by the ionizing radiation total-dose effect, improves the ionizing radiation resistance of the circuit, reduces the chip layout area, and can be applied into the large scale integrated circuit system.