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External preparation for treating seborrheic dermatitis

A technology for seborrheic dermatitis and external preparations, which is applied in the field of external preparations for the treatment of seborrheic dermatitis, can solve the problems of only treating the symptoms, ignoring the pathogenesis, and failing to cure the root causes, and achieves quick effects, no toxic side effects and safe use. Effect

Inactive Publication Date: 2010-06-02
HUAZHONG NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These external liniments focus too much on the anti-inflammatory effect, while ignoring the pathogenesis, they can only treat the symptoms, not the root cause

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Glucan, xyloglucan, seaweed polysaccharide, laminarin, heparin, pectin, chitosan, astragalus polysaccharide, pokeweed polysaccharide, angelica polysaccharide, achyranthes polysaccharide, medlar polysaccharide, poria cocos polysaccharide, tremella polysaccharide, tamarind Polysaccharide, Yunzhi polysaccharide, Ganoderma lucidum polysaccharide, Lentinan, Flammulina velutipes polysaccharide, Kiwi fruit polysaccharide, Epimedium polysaccharide, Acanthopanax polysaccharide, Mushroom polysaccharide, Pullulan polysaccharide, Ginseng polysaccharide, Ruozhu polysaccharide, Safflower polysaccharide, Bagasse polysaccharide, Ligustrum lucidum polysaccharide, Tetrandrine, Bamboo yellow polysaccharide, Pullulan, tea polysaccharide, Schizophyllum polysaccharide, Polyporus polysaccharide, Cordyceps polysaccharide, Bright fungus polysaccharide, Hericium erinaceus polysaccharide and other Chinese herbal polysaccharides One or more kinds are dissolved in water to prepare a solution of 0.01%...

Embodiment 2

[0033] Erythromycin, chloramphenicol, chloramphenicol, lincomycin hydrochloride, tobramycin, natamycin, norfloxacin, meperifamycin, cyclosporine, gentamicin One or several bactericidal antibiotics in neomycin, soluble in water according to 0.005-10% of the total weight of the external agent, add glucan, xyloglucan, seaweed polysaccharide, laminarin, heparin, fruit Gum, Chitosan, Astragalus Polysaccharide, Pokeweed Polysaccharide, Angelica Polysaccharide, Achyranthes Polysaccharide, Lycium Barbarum Polysaccharide, Poria Polysaccharide, Tremella Polysaccharide, Tamarind Polysaccharide, Yunzhi Polysaccharide, Ganoderma Polysaccharide, Lentinan Polysaccharide, Flammulina velutipes Fruit Body Polysaccharide, Kiwi Fruit Polysaccharide , Epimedium polysaccharide, Acanthopanax polysaccharide, Mushroom polysaccharide, Pullulan polysaccharide, Ginseng polysaccharide, Ruozhu polysaccharide, Safflower polysaccharide, Bagasse polysaccharide, Ligustrum lucidum polysaccharide, Tetrandrine poly...

Embodiment 3

[0035] Preparation of topical lotion for treating seborrheic dermatitis

[0036] Dissolve 5 grams of seaweed polysaccharide in 1 kg of water, and then dissolve 3 grams of gentamicin in the seaweed polysaccharide aqueous solution. Dissolve 5 grams of ivermectin in 50ml of ether, add the ether solution of ivermectin to the polysaccharide system, vacuum or heat to 35°C, remove the ether, and prepare a topical lotion for treating seborrheic dermatitis.

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PUM

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Abstract

The invention relates to an external preparation for treating seborrheic dermatitis, comprising at least one effective parasite-expelling medicament which is extracted from etreptomyces and used as an active component, i.e. large ring lactone, such as abamectin, or chemical modified or synthetic derivative ivermectin, one or more of bactericidal antibiotics in erythrocin, aureomycin, chloromycetin, lincomycin hydrochloride, tobramycin, natamycin, norfloxacin, rifampicin, cyclosporine, gentamicin and neomycin and at least another traditional Chinese medical herbal amylase which are contained in carriers for the surface administration and the cutaneous penetration of the active component, or suitable amounts of glucose, sodium chloride or potassium chloride can be also added to the external preparation. The invention has rapid constringency and demanded efficacy for the seborrheic dermatitis, little excitation irritation to the skin, extremely mild skin peeling without obvious toxic and side effects; and the preparation process can ensure the chemical stabilities of various contents in the production process. The invention can be also used for treating whelks.

Description

Technical Field: [0001] The invention relates to a topical agent for treating seborrheic dermatitis, and has extremely high safety. Background technique: [0002] Seborrheic dermatitis Seborrheic dermatitis, also known as seborrheic eczema and seborrhea, is a chronic superficial inflammatory disease of the skin that can affect many parts of the body, including the scalp, eyebrows, nasolabial folds, lip , Ears, chest, sternum area, armpits, submammary folds, umbilicus, groin and gluteal folds. The disease is characterized by many shapes, sizes, and surface textures, and is often scab-like, yellowish and accompanied by itching. The etiology, pathogenesis and histology of seborrheic dermatitis are not yet clear. It may be based on excessive seborrhea, secondary to fungi (Pityrosporum ovale) and bacteria (Propionibacterium azoles) Parasitic or dermatitis caused by the increase of free fatty acids on the skin surface. Excessive seborrhea may be related to genetic factors, neuropsyc...

Claims

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Application Information

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IPC IPC(8): A61K31/716A61K31/722A61K31/727A61K33/14A61K31/732A61K36/02A61K36/481A61K36/185A61K36/232A61K36/21A61K36/815A61K36/076A61K36/06A61K36/074A61K36/296A61K36/254A61K36/888A61K36/258A61K36/899A61K36/286A61K36/59A61K36/82A61K36/068A61P17/08A61P31/04A61K31/7048A61K31/65A61K31/165A61K31/7056A61K31/702A61K31/496A61K38/13A61K31/7036A61K31/7004
Inventor 曹郁
Owner HUAZHONG NORMAL UNIV
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